Results 41 to 50 of about 115,881 (249)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Food fraud threats in UK post-harvest seafood supply chains; an assessment of current vulnerabilities

npj Science of Food
Seafood fraud is commonly reported on food fraud databases and deceptive practices are highlighted by numerous studies, with impacts on the economy, health and marine conservation.
Sophie Lawrence, Christopher Elliott, Wim Huisman, Moira Dean, Saskia van Ruth   +4 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Electrochemical Membrane Reactors for Sustainable Chlorine Recycling

Membranes, 2012
Polymer electrolyte membranes have found broad application in a number of processes, being fuel cells, due to energy concerns, the main focus of the scientific community worldwide.<strong> </strong>Relatively little attention has been paid to
Ulrich Kunz, Thomas Turek, Kai Sundmacher, Rafael Kuwertz, Tanja Vidakovic-Koch, Isai Gonzalez Martinez   +5 more
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Synthesis of Highly Crystalline Graphite from Spontaneous Ignition of In Situ Derived Acetylene and Chlorine at Ambient Conditions

Molecules, 2020
We exploited a classic chemistry demonstration experiment based on the reaction of acetylene with chlorine to obtain highly crystalline graphite at ambient conditions. Acetylene and chlorine were generated in-situ by the addition of calcium carbide (CaC2)
Nikolaos Chalmpes, Konstantinos Spyrou, Athanasios B. Bourlinos, Dimitrios Moschovas, Apostolos Avgeropoulos, Michael A. Karakassides, Dimitrios Gournis   +6 more
doaj   +1 more source

Using Technical and Financial Review and AHP Method to Find the Best Method of the Chlorine-Based Disinfection [PDF]

علوم و مهندسی آب و فاضلاب, 2017
In this paper, research on six chlorine-based methods, which is one of the most widely used and effective methods of disinfection, is carried out, the advantages and disadvantages and their comparisons have been investigated.Also provided by Excel ...
Ebrahim Aboutalebi Shakour, Hosein Jamshidi   +1 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Unprecedented Harmful algal bloom in the UK and Ireland’s largest lake associated with gastrointestinal bacteria, microcystins and anabaenopeptins presenting an environmental and public health risk

Environment International
Harmful Algal Blooms (HABs) are outbreaks of aquatic toxic microalgae emerging as a global problem driven by nutrient enrichment, global climate change and invasive species.
Neil Reid, Marina I. Reyne, William O’Neill, Brett Greer, Qiqi He, Oliver Burdekin, John W. McGrath, Chris T. Elliott   +7 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source