Results 251 to 260 of about 243,077 (307)

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source

Pharmacological properties of the ethnomedicinal plant <i>Dodonaea viscosa</i>: Anticancer potential and beyond (Review). [PDF]

Biomed Rep
Saferdien A, Yekelo B, Mowla S.
europepmc   +1 more source

Deciphering the Evolution Pattern of Structural Variations Overlapped With Repetitive Sequence During Cattle Evolution

Advanced Science, EarlyView.
The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo, Jinxiu Li, Adeniyi C. Adeola, Xueyan Jiang, Juntao Ma, Jian Xiao, Dexiang Hu, Kaixing Qu, Haihong Wu, Junren Chen, Zhanxing He, Tingting Yin, Ali Esmailizadeh, Jing Luo, Olivier Hanotte, Ya‐Ping Zhang, Yan Li   +16 more
wiley   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Sterol Composition in the Lichens Lobaria pulmonaria and Lobaria retigera: Does Photobiont Matter? [PDF]

Int J Mol Sci
Valitova JN, Khabibrakhmanova VR, Babayev VM, Khajrullina AF, Gurjanov OP, Gazizova NI, Beckett RP, Minibayeva FV.   +7 more
europepmc   +1 more source

Antileishmanial Activities of Methanol Extract and Solvent Fraction of <i>Clematis simensis</i> Fresen Roots. [PDF]

Adv Pharmacol Pharm Sci
Megersa A, Nardos A, Ketema T, Deyno S.
europepmc   +1 more source

Exploring differential production of alkaloids and terpenoids in Cristataspora coffeata (Berk:) Robledo (Ganodermataceae) under submerged culture. [PDF]

PLoS One
González-Hernández RA, Villanueva-Silva R, Arganis-Ramírez CA, Valdez-Cruz NA, Trujillo-Roldán MA.   +4 more
europepmc   +1 more source

<i>Theobroma cacao</i> seed extracts attenuate dyslipidemia and oxidative stress in L-NAME induced hypertension in Wistar rats. [PDF]

Int J Med Sci
Agwupuye EI, Agboola AR, Kuo YC, Itam AH, Ezeayinka LU, Atangwho IJ, Ayeyemi BM, Edema AA, Lawal B, Alotaibi MO, Almohmadi NH, Batiha GE, El-Sabbagh NM, Huang HS.   +13 more
europepmc   +1 more source

In Vivo Wound Healing and Antimicrobial Activities of the Hydroalcoholic Extract and Solvent Fractions of <i>Arisaema schimperianum</i> Schott. (Araceae) Tuber in Mice. [PDF]

Biomed Res Int
Awoke B, Bisrat D, Gebreamlak B, Abebe A, Degu S, Asres K.   +5 more
europepmc   +1 more source

In vitro and in silico analysis of the fungicidal potential of secondary metabolites from a bacterial endophyte against Botrytis cinerea. [PDF]

BMC Biotechnol
Maumela P, Serepa-Dlamini MH.
europepmc   +1 more source