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Effect of chlorogenic acid on hydroxyl radical
Molecular and Cellular Biochemistry, 2003Chlorogenic acid (CGA) is considered to act as an antioxidant. However, the inhibitory effects of CGA on specific radical species are not well understood. Electron spin resonance (ESR) in combination with spin trapping techniques was utilized to detect free radicals.
Lun-Yi, Zang +4 more
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Absorptive profile of chlorogenic acid in rats
Die Pharmazie, 2007The objective of this work was to systematically investigate the absorptive profile of chlorogenic acid (CGA) in rats and to increase its intestinal absorption using absorption enhancers. The rat in situ intestinal perfusion technique was used to examine absorptive rate and extent of CGA.
Jing, Ren +5 more
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Phytochemistry, 1966
Abstract Experiments in which potato tuber slices were maintained on a tracer amount of [α- 14 C]cinnamic acid and synthetic 3- 0 -cinnamoylquinic acid (pH adjusted to 6) showed that if this conjugate is a free intermediate in chlorogenic acid (3- 0 -caffeoylquinic acid) formation, then the active pool of the compound is very small and is contained ...
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Abstract Experiments in which potato tuber slices were maintained on a tracer amount of [α- 14 C]cinnamic acid and synthetic 3- 0 -cinnamoylquinic acid (pH adjusted to 6) showed that if this conjugate is a free intermediate in chlorogenic acid (3- 0 -caffeoylquinic acid) formation, then the active pool of the compound is very small and is contained ...
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Chlorogenic acid as a competitive inhibitor of indoleacetic acid oxidase
Archives of Biochemistry and Biophysics, 1957Abstract An enzyme system oxidizing indoleacetic acid was isolated from pea epicotyls. It had an optimal activity at pH 5.6. Chlorogenic acid was a competitive inhibitor for the oxidase in vitro. Caffeic acid inhibited IAA oxidase in a noncompetitive fashion, and quinic acid, the other moiety of chlorogenic acid, was inactive.
R S, RABIN, R M, KLEIN
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On enzyme inhibition by oxidized chlorogenic acid
Life Sciences, 1964Abstract The inhibiting action of oxidized chlorogenic acid (Ox-CGA) on the activity of several enzymes has been investigated. A comparative analysis of the effects of Ox-CGA with those of p-hydroxy-mercuri-benzoate seems to exclude the -SH groups of the proteins as the main site of action of Ox-CGA.
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On the distribution of caffeic acid and the chlorogenic acid isomers in plants
Archives of Biochemistry and Biophysics, 1958Abstract 1. 1. The silicic acid column technique described by Bulen et al. (9) has been used in a study of the distribution of caffeic acid and chlorogenic acid isomers in plants. Ultraviolet-absorption measurements and titration with alkali were used for the detection of these acids. 2. 2. Resolution into five bands was achieved.
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