Results 121 to 130 of about 138,311 (269)
Long‐Term Dermoscopic Evolution of Reticular Erythematous Mucinosis: Case Report
JEADV Clinical Practice, EarlyView.ABSTRACT Reticular erythematous mucinosis is a rare dermatosis with a challenging diagnosis. To date, its dermoscopic features have not been well characterised in the literature. Only a limited number of case reports have described dermoscopic findings that may be indicative of the disorder, including the presence of dotted and linear vessels, as well ...
Grażyna Kamińska‐Winciorek +4 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo +8 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Insulin secretion is a complex, vesicular transport process. Rab34 is a key regulator of intracellular vesicle transport; however, its role in insulin secretion has not yet been reported. miRNA‐9 is vital for the development and progression of the diagnosis and treatment of type 2 diabetes. This study aimed to investigate whether miR‐9 targets
Zhen‐Zhen Guo +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose EZH2 (enhancer of zeste homologue 2) inhibitors are an emerging class of drugs that target epigenetic regulation. However, their efficacy in solid tumours has been limited, partly due to drug‐induced upregulation of fatty acid synthesis.
Rui Cheng +10 more
wiley +1 more source
"THE EFFECT OF CHLOROQUINE ON THE INFECTIVITY OF RODENT MALARIA PARASITES TO ANOPHELES STEPHENSI " [PDF]
Iranian Journal of Public Health, 1977 There was a statistically significant difference in the number of oocysts, developed in Anopheles stephensi which had fed on mice infected with chloroquine resistant strains (NY 151./2B and. P.y.
A.N., Hamidi
doaj
Cancer Science, EarlyView.OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan +8 more
wiley +1 more source
Artemisinin: From Chinese Herbal Medicine to Modern Chemotherapy [PDF]
, 2019 Malaria is a disease that has blighted humankind since early times. The first antimalarial treatment available to Europeans was the dried bark of the cinchona tree from Peru. The main problem in its use was adulteration by other material.
Butler, Anthony
core +1 more source
Cancer Science, EarlyView.In tumor cells, MHC‐I is typically degraded through autophagy, leading to reduced antigen presentation. However, Fangji Huangqi Decoction (FJHQ), acting as an autophagy inhibitor, suppresses lysosomal acidification, which in turn inhibits the degradation of MHC‐I. This results in increased surface expression of MHC‐I on tumor cells.
Yuxiao Jiang +18 more
wiley +1 more source