Results 131 to 140 of about 93,237 (289)

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola

Chemistry &Biodiversity, EarlyView.
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel, Ângela Liberal, Tiane C. Finimundy, Tânia S. P. Pires, Pedro Cravo, Maria Conceição Silva, Gustavo Capatti Cassiano, Lillian Barros, Maria M. Romeiras, Ângela Fernandes   +9 more
wiley   +1 more source

Synthesis and In Vitro Activity of Hypofuran B and Analogs Against Plasmodium Falciparum and Trypanosoma Cruzi

ChemMedChem, EarlyView.
Hypofuran B, drynaran, and a series of analogs are obtined by crossed aldol condensation from furfural dereivatives. Compunds are tested for in vitro activity agaisnt Trypanosoma cruzi and Plasmodium falciparum. Best results are obtained Against P. falciparum, with IC50 values ranging from 5,35 to 10,35 µg mL−1.
Cristiane Aparecida Franco, Jodieh Oliveira Santana Varejão, Isabela Penna Ceravolo, Victória Miranda Machado, Antoniana Ursine Krettli, Daniela de Melo Resende, Silvane Maria Fonseca Murta, Felipe Terra Martins, Eduardo Jorge Pilau, Vinícius Ribeiro Montes, Markus Kohlhoff, Eduardo V. V. Varejão   +11 more
wiley   +1 more source

Chloroquine Neuromyopathy [PDF]

BMJ, 1964
T B, BEGG, J A, SIMPSON
openaire   +2 more sources

A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19

, 2020
Andrea Cortegiani, Giulia Ingoglia, Mariachiara Ippolito, Antonino Giarratano, Sharon Einav   +4 more
openalex   +2 more sources

A Case of Chloroquine-Induced Cardiomyopathy That Presented as Sick Sinus Syndrome [PDF]

, 2010
Jae Hak Lee, Woo‐Baek Chung, Ju Hyun Kang, Hyung Woo Kim, Jin Jin Kim, Ji Hyun Kim, Hui‐Jeong Hwang, Jea Beom Lee, Jong Won Chung, Hyo Lim Kim, Yun Seok Choi, Chul Soo Park, Ho‐Joong Youn, Man Young Lee   +13 more
openalex   +1 more source

Supplementary Figure 6 from Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER⁺ Breast Cancer

, 2023
Katherine L. Cook, Anni Wärri, David R. Soto‐Pantoja, Pamela AG. Clarke, M. Idalia Cruz, Alan Zwart, Robert Clarke   +6 more
openalex   +1 more source

Exploration and Characterization of the Antimalarial Activity of Pyrimidine‐2,4‐Diamines for which Resistance is Mediated by the ABCI3 Transporter

ChemMedChem, EarlyView.
Investigation of the structure‐activity relationship on W482 (1) with a pyrimidine‐2,4‐diamine scaffold culminated in analog 51 with enhanced anti‐plasmodial activity. Forward genetics and phenotypic examination revealed the ABCI3 transporter protein as a putative resistance mechanism.
Mahta Mansouri, Madeline G. Dans, Zijun Low, Katie Loi, Kate E. Jarman, Jocelyn S. Penington, Deyun Qiu, Adele M. Lehane, Benigno Crespo, Franciso‐Javier Gamo, Delphine Baud, Stephen Brand, Paul F. Jackson, Alan F. Cowman, Brad E. Sleebs   +14 more
wiley   +1 more source

Chemotherapy of Glomerulonephritis, Particulary on the Treatment with Chloroquine

, 1960
S. Tsuji, Yoshikazu Fujita, Mutsumi NISHIGUCHI, SHIN KUBOTA, ICHIRO KORI, Yojiro HIROSE, H. Koyama, Kazuya WAIMATSU, Shusaku Tominaga, Kayo Fujita, Kazuyoshi Hiwasa, CHISATO AKAI, Naohiro Tanaka, Masato Izumi   +13 more
openalex   +2 more sources

Chloroquine or hydroxychloroquine for prophylaxis of COVID-19 [PDF]

, 2020
Nicola Principi, Susanna Esposito
openalex   +1 more source

Searching for Novel Antiviral Agents as COVID19 Treatments: Guanidino Diaryl Thioureas

ChemMedChem, EarlyView.
Structure of the "hit‐compound" found and the proposed interaction with the active site of the TMPRSS2 protease, involving a reversible mechanism of action, are shown. The COVID‐19 pandemic highlighted the urgent need for effective antiviral treatments targeting SARS‐CoV‐2.
Marco Minneci, Barbara Farkaš, Adeyemi Rahman, Amy Kempf, Inga Nehlmeier, Stefan Pöhlmann, Isabel Rozas   +6 more
wiley   +1 more source