Chloroquine Is a Zinc Ionophore [PDF]
PLoS ONE, 2014 Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to sensitize cancerous cells to chemotherapy, radiation ...
Wei-Qun Ding +2 more
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Pharmacology Progresses and Applications of Chloroquine in Cancer Therapy [PDF]
International Journal of NanomedicineYanqing Liu,1,* Yuqing Meng,1,* Junzhe Zhang,1 Liwei Gu,1 Shengnan Shen,1 Yongping Zhu,1 Jigang Wang1,2 1State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-Di Herbs, Artemisinin Research Center, and Institute of Chinese Materia
Jigang Wang, Liwei Gu, Yongping Zhu
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Chloroquine Resistant Plasmodium vivax: In Vitro Characterisation and Association with Molecular Polymorphisms [PDF]
PLoS ONE, 2007 Treatment failure of chloroquine for P. vivax infections has reached high levels in the eastern provinces of Indonesia, however, in vitro characterization of chloroquine resistance and its associated molecular profile have yet to be determined.Using a ...
Qin Cheng +2 more
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Variation of the Chloroquine Resistance Transporter (Crt) Gene in Chloroquine-Resistant and Chloroquine-Sensitive Plasmodium berghei [PDF]
Iranian Journal of Parasitology, 2008 Background: The emergence and spread of chloroquine resistant Plasmodium falciparum in the world stimulated some investigators to consider different aspects of chloroquine resistance in human and rodent Plasmodia.
N Ghobakhloo +5 more
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Cells, 2023 Lysosomotropic agent chloroquine was shown to sensitize non-stem glioblastoma cells to radiation in vitro with p53-dependent apoptosis implicated as one of the underlying mechanisms. The in vivo outcomes of chloroquine or its effects on glioblastoma stem
Andreas Müller +11 more
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DOES ORAL CHLOROQUINE AFFECT THE HIPPOCAMPUS IN RATS? A CLUE TO CHLOROQUINE INDUCED NEUROPSYCHIATRIC ADVERSE EFFECTS [PDF]
Ain Shams Medical Journal, 2020 Background: Chloroquine is widely used in medicine. The main indication for its usage is treatment of malaria. Reportsabout psychiatric side effects of chloroquine are rare.
Ahmed Al-Neklawy
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Do Chloroquine and Hydroxychloroquine Treat COVID-19? [PDF]
, 2021 Chloroquine is an anti-malarial and autoimmune disease drug, which has an anti- viral activity. In vitro, the Chloroquine and Hydroxychloroquine are potent at inhibiting SARS-CoV.
Sanaa Bouchnafati +3 more
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Neurological and psychiatric safety of tafenoquine in Plasmodium vivax relapse prevention: a review
Malaria Journal, 2020 Background Tafenoquine is an 8-aminoquinoline anti-malarial drug recently approved as a single-dose (300 mg) therapy for Plasmodium vivax relapse prevention, when co-administered with 3-days of chloroquine or other blood schizonticide. Tafenoquine 200 mg
Stephan Duparc +4 more
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A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria. [PDF]
PLoS ONE, 2012 The predominance of chloroquine-susceptible falciparum malaria in Malawi more than a decade after chloroquine's withdrawal permits contemplation of re-introducing chloroquine for targeted uses.
Miriam K Laufer +8 more
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Journal of Ophthalmology, 2021 The article is on an important subject, chloroquine maculopathy associated with long-term use of chloroquine. Given that chloroquine has been widely used for the treatment of COVID-19, it is important to accumulate data on adverse reaction to chloroquine
N. V. Malachkova, T. Ie. Kozlova
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