The Nephrotoxic Effect of Chloroquine, The OFF-Label Anti COVID 19 and Possible Protective Role of Ginkgo Biloba Extract in Male Albino Rats [PDF]
BACKGROUND: Chloroquine is a historical antimalarial drug with nephrotoxic potentialin overdose. Lately, it has been tried for COVID 19 therapy. Ginkgo biloba leaves extract is an effective antioxidant and free radical hunter.
Nadia Helal +6 more
doaj +1 more source
Background As a result of widespread chloroquine and sulphadoxine-pyrimethamine (SP) resistance, 90% of sub-Saharan African countries had adopted policies of artemisinin-based combination therapy (ACT) for treatment of uncomplicated malaria by 2007.
Venkatesan Meera +2 more
doaj +1 more source
The multifocal pattern electroretinogram in chloroquine retinopathy [PDF]
Purpose: Optimal screening for ocular toxicity caused by chloroquine and hydroxychloroquine is still controversial. With the multifocal pattern electroretinogram (mfPERG), a new electrophysiological technique has recently become available to detect early
Stiefelmeyer, S. +4 more
core +1 more source
Azithromycin plus chloroquine: combination therapy for protection against malaria and sexually transmitted infections in pregnancy. [PDF]
INTRODUCTION: The first-line therapy for the intermittent preventive treatment of malaria in pregnancy (IPTp) is sulphadoxine-pyrimethamine (SP).
Chandramohan, Daniel +3 more
core +1 more source
Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso [PDF]
Mueller O, Razum O, Traore C, Kouyate B. Community effectiveness of chloroquine and traditional remedies in the treatment of young children with falciparum malaria in rural Burkina Faso. Malaria Journal.
Kouyate Bocar +11 more
core +1 more source
Persistence of chloroquine-resistant haplotypes of Plasmodium falciparum in children with uncomplicated Malaria in Lagos, Nigeria, four years after change of chloroquine as first-line antimalarial medicine. [PDF]
BACKGROUND: In Nigeria, despite the change in National malaria drug policy to artemisinin combination therapy (ACT) in 2005 due to widespread chloroquine resistance, chloroquine (CQ) is still widely used in the treatment of malaria because it is cheap ...
Sutherland, Colin J +2 more
core +1 more source
Dihydroartemisinin-piperaquine versus chloroquine to treat vivax malaria in Afghanistan: an open randomized, non-inferiority, trial. [PDF]
BACKGROUND: Afghanistan's national guidelines recommend chloroquine for the treatment of Plasmodium vivax infection, the parasite responsible for the majority of its malaria burden. Chloroquine resistance in P. vivax is emerging in Asia.
Faizullah Kaker +29 more
core +1 more source
Clinical and parasitological response to oral chloroquine and primaquine in uncomplicated human Plasmodium knowlesi infections. [PDF]
BACKGROUND: Plasmodium knowlesi is a cause of symptomatic and potentially fatal infections in humans. There are no studies assessing the detailed parasitological response to treatment of knowlesi malaria infections in man and whether antimalarial ...
Cox-Singh, J +36 more
core +1 more source
Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy. [PDF]
In the high malaria-transmission settings of sub-Saharan Africa, malaria in pregnancy is an important cause of maternal, perinatal and neonatal morbidity.
Chandramohan, Daniel +11 more
core +1 more source
Background Chloroquine treatment for Plasmodium falciparum has been discontinued in almost all endemic regions due to the spread of resistant isolates. Reversal of chloroquine susceptibility after chloroquine discontinuation has been reported in dozens ...
Makoto Sekihara +10 more
doaj +1 more source

