Results 221 to 230 of about 125,568 (336)

Shedding Light on the Cellular Uptake Mechanisms of Bioactive Glass Nanoparticles as Controlled Intracellular Delivery Platforms: A Review of the Recent Literature

Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.
This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda, Aldo R. Boccaccini   +1 more
wiley   +1 more source

Quantification of Interactions between Small Molecules and RNA Probes Representative of Myotonic Dystrophy Type 1 Using Affinity Capillary Electrophoresis and UPLC-UV. [PDF]

ACS Omega
Leveque M, Wells M, Beukens D, Lefebvre V, Hambye S, Blankert B.   +5 more
europepmc   +1 more source

Chloroquine toxicity of the retinal pigment epithelium and retina in vitro and a mouse model of retinal toxicity

, 2016
Dhanesh Amarnani, Leo A. Kim, Patrìcia A. D'Amore, Lindsay L. Wong   +3 more
openalex   +1 more source

Magnetic Bioprinting and Actuation of Stretchable Muscle Tissue

Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Human and murine myoblasts labeled with iron oxide nanoparticles are magnetically bioprinted into wrench‐shaped tissues, which are then anchored between two magnetic needles. Mechanical stretching of these tissues enhances both their maturation and functional performance. Abstract Engineering tissues with precise, long‐lasting shapes and the capability
Noam Demri, Lise Morizur, Simon Dumas, Giacomo Gropplero, Cécile Martinat, Stéphanie Descroix, Claire Wilhelm   +6 more
wiley   +1 more source

Fast-Acting Chalcogen-Phosphoranes Inhibit Sensitive and Resistant <i>Plasmodium falciparum</i> Strains. [PDF]

ACS Omega
Moura IMR, Barbosa CS, Mendes GR, Aguiar ACC, Cruz FC, Menezes PH, Guido RVC.   +6 more
europepmc   +1 more source

Obesity‐Associated TRIM15 Promotes the Proliferation of Esophageal Adenocarcinoma Through the YY2/FOXRED1 Axis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang, Chong Yang, Dayuan Luo, Pingting Liu, Zhen Zeng, Weilin Peng, Dongzi Peng, Hao Su, Xiaoxiong Xiao, Haiqin Wang, Xin Jin   +10 more
wiley   +1 more source

Safety and Efficacy of 3 Alternative Regimens Against Relapsing Plasmodium vivax Malaria in Glucose 6-Phosphate Dehydrogenase-Deficient Patients in the Brazilian Amazon (ALTPRIM). [PDF]

Clin Infect Dis
Barbosa L, Brito-Sousa J, Nascimento C, Pacheco A, Alexandre M, Alencar A, Melo M, Omena A, Souza I, Silva E, Queiroz M, Siqueira V, Rabelo C, Baía-da-Silva D, Silva D, Rocha Y, Barbosa A, Castro R, Almeida A, Brito M, Lopes A, Balieiro A, Costa M, Amaral T, Valle C, Vieira A, Gonzaga J, Pereira D, Alecrim M, Monteiro W, Lacerda M, Melo G.   +31 more
europepmc   +1 more source

Lymphocyte proliferative response and subset profiles during extended periods of chloroquine or primaquine prophylaxis [PDF]

, 1996
D J Fryauff, Allen L. Richards, J. Kevin Baird, Thomas L. Richie, Eric Mouzin, Emiliana Tjitra, Mochammad A. Sutamihardja, Sutanti Ratiwayanto, Hilda Hadiputranto, Ria P. Larasati, Nurani Pudjoprawoto, Budi Subianto, Stephen L. Hoffman   +12 more
openalex   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, Volume 13, Issue 1, 5 January 2026.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Drug Repurposing as an Effective Drug Discovery Strategy: A Critical Review. [PDF]

Drug Des Devel Ther
Al Khzem AH, Wali SM.
europepmc   +1 more source