Results 231 to 240 of about 178,293 (355)

Modulation of Autophagy by Ursolic and Betulinic Acids: Distinct Cytotoxic and Membrane‐Disruption in Malignant and Nonmalignant Cells

open access: yesCell Biology International, Volume 49, Issue 11, Page 1518-1536, November 2025.
ABSTRACT Autophagy is a critical adaptive mechanism in tumor cells that promotes survival under stress, but when dysregulated, it may trigger programmed cell death. The pentacyclic triterpenoids betulinic acid (BA) and ursolic acid (UA) are structurally related compounds that modulate autophagy; however, comparative insights into their effects on ...
Waleska Kerllen Martins   +8 more
wiley   +1 more source

Issues associated with malaria self-medication in sub-Saharan Africa: A systematic literature review and meta-analysis. [PDF]

open access: yesMalariaworld J
Amaka JI   +9 more
europepmc   +1 more source

Effect and Mechanisms of Yiqi Jianpi Xiaoyu Prescription on Kidney Fibrosis on the Basis of Metabolomics and Experimental Validation

open access: yesFood Science &Nutrition, Volume 13, Issue 11, November 2025.
Our results demonstrate that YQJPXY alleviates fibrosis by regulating key metabolites, including adenosine, adenine, and inosine, and activates autophagy through the A2BR/cAMP/AMPK pathway. ABSTRACT The Yiqi Jianpi Xiaoyu prescription (YQJPXY) exhibits ameliorative effects on kidney fibrosis, but the underlying mechanism related to metabolism remains ...
Keda Lu   +6 more
wiley   +1 more source

Characterizing the quick-killing mechanism of action of azithromycin analogs against malaria parasites. [PDF]

open access: yesAntimicrob Agents Chemother
Mao EY   +16 more
europepmc   +1 more source

The Molecular Basis of the Action of Chloroquine in Porphyria Cutanea Tarda

open access: bronze, 1973
Perry L. Scholnick   +2 more
openalex   +1 more source

Sorption and desorption behavior of hydroxychloroquine and ivermectin in WWTP sludge: kinetic and equilibrium insights

open access: yesJournal of Chemical Technology &Biotechnology, Volume 100, Issue 11, Page 2357-2370, November 2025.
Abstract BACKGROUND Domestic sewage is one of the main pathways for the introduction of pharmaceutical contaminants into environmental compartments. During the COVID‐19 pandemic, the consumption of medications such as hydroxychloroquine (HCQ) and ivermectin (IVM) increased significantly, resulting in a greater presence of these substances in ecosystems.
Bruna Giovana Locatelli   +3 more
wiley   +1 more source

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