Results 41 to 50 of about 8,069 (212)

Early in‐hospital treatment of acute heart failure. Part 2 of the international expert opinion series on AHF management

ESC Heart Failure, Volume 12, Issue 6, Page 3826-3843, December 2025.
This state‐of‐the‐art review outlines a practical, evidence‐based framework for early acute heart failure management to address critical gaps in current guidance and improve early treatment outcomes. Key components include early identification of co‐existing conditions, bedside haemodynamic profiling, a structured diagnostic approach incorporating both
Anika S. Naidu, Andrew P. Ambrosy, Gad Cotter, Edimar A. Bocchi, Javed Butler, Ovidiu Chioncel, Beth Davison, Anastase Dzudie, Yonathan Freund, Marat Fudim, Sivadasanpillai Harikrishnan, Ivna G. Cunha, Alexandre Mebazaa, Robert J. Mentz, Òscar Miró, Siti E. Nauli, Mateo Pagnesi, Naoki Sato, Gianluigi Savarese, Karen Sliwa‐Hahnle, Yuhui Zhang, Jingmin Zhou, Jan Biegus   +22 more
wiley   +1 more source

Istodobno spektrofotometrijsko određivanje losartan kalija, amlodipin besilata i hidroklorotiazida u farmaceutskim pripravcima kemometrijskom metodom [PDF]

, 2010
In the present work, four different spectrophotometric methods for simultaneous estimation of losartan potassium, amlodipine besilate and hydrochlorothiazide in raw materials and in formulations are described.
A. Sankar, A. Santha, D. Hertzog, D. Nagavalli, E. Dinç, E. Dinç, F. Belal, G. Flåten, H. Martens, I. Palabiyik, K. Nagaraj, M. Ferro, M. Malesuik, M. Obando, M. Polinko, N. Erk, O. Divya, O. Lastra, R. Barman, R. Brereton, R. Brereton, R. Bro, R. Kakde, R. Kramer, S. Shah, V. Vaidhyalingam, Y. Ma   +26 more
core   +2 more sources

The Concise Guide to PHARMACOLOGY 2025/26: Transporters

British Journal of Pharmacology, Volume 182, Issue S1, Page S404-S496, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Laura Amarosi, Catriona M. H. Anderson, Philip M. Beart, Stefan Broer, Paul A. Dawson, Gergely Gyimesi, Bruno Hagenbuch, James R. Hammond, Jules C. Hancox, Michal Hershfinkel, Ken‐ichi Inui, Yoshikatsu Kanai, Stephan Kemp, Edmund R. S. Kunji, Gavin Stewart, Sotiria Tavoulari, David T. Thwaites, Tiziano Verri   +28 more
wiley   +1 more source

Prediction of the permeability of neutral drugs inferred from their solvation properties [PDF]

, 2015
Determination of drug absorption is an important component of the drug discovery and development process in that it plays a key role in the decision to promote drug candidates to clinical trials.
Milanetti, Edoardo, Raimondo, Domenico, Tramontano, Anna   +2 more
core   +1 more source

A Review of Global Optimization Methods for Molecular Structures: Algorithms, Applications and Perspectives

Journal of Computational Chemistry, Volume 46, Issue 28, October 30, 2025.
This image categorizes global optimization methods into stochastic and deterministic approaches. Stochastic methods include techniques like Genetic Algorithms, Simulated Annealing, and Machine Learning, often involving randomness. Deterministic methods, such as Molecular Dynamics and Single‐Ended methods, follow defined rules without randomness.
Jorge Alberto Sanchez Alvarez, Patrizia Calaminici   +1 more
wiley   +1 more source

A combined clinical and biomarker approach to predict diuretic response in acute heart failure [PDF]

, 2015
Background: Poor diuretic response in acute heart failure is related to poor clinical outcome. The underlying mechanisms and pathophysiology behind diuretic resistance are incompletely understood.
Bloomfield, Daniel M., Bruno, Noemi, Cleland, John G.F., Cotter, Gad, Damman, Kevin, Davison, Beth, Dittrich, Howard C., Givertz, Michael M., Hillege, Hans L., Metra, Marco, O’Connor, Christopher M., Ponikowski, Piotr, Teerlink, John R., ter Maaten, Jozine M., Valente, Mattia A.E., van Veldhuisen, Dirk J., Voors, Adriaan A.   +16 more
core   +4 more sources

A good‐practice guide to solving and refining molecular organic crystal structures from laboratory powder X‐ray diffraction data

Acta Crystallographica Section C, Volume 81, Issue 10, Page 559-569, October 2025.
A step‐by‐step outline for academic and industrial practitioners determining molecular organic crystal structures from powder X‐ray diffraction data.This article focuses on a specific real‐space methodology for solving and refining molecular organic crystal structures, developed by the authors and collaborators.
Elena Kabova, Margarita Mersiyanova, Kenneth Shankland, Norman Shankland, Mark Spillman   +4 more
wiley   +1 more source

Development and Application of HPLC-MS/MS Method for Determination of Human Pharmaceuticals and Synthetic Hormones in River Water and Sewage Effluents [PDF]

, 2010
Pollution of the aquatic environment by residues of human pharmaceuticals and synthetic hormones has become a cause for increasing concern in recent years and acknowledged as one of the most emerging environmental issues.
Al-Odaini, Najat Ahmed
core  

Micro-RNA family that modulates fibrosis and uses thereof [PDF]

, 2017
The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response
Olson, Eric N., van Rooij, Eva
core   +1 more source

Fenoldapam for Acute Kidney Injury in Children [PDF]

, 2008
We report two cases of children with severe cardiomyopathy requiring treatment with ventricular assist devices who developed acute kidney injury and were treated with fenoldopam.
Andreoli, Sharon P., Knoderer, Chad A., Leiser, Jeffrey D., Nailescu, Corina, Turrentine, Mark W.   +4 more
core   +1 more source