Results 71 to 80 of about 5,213 (178)
Effects of chlorothiazide on working capacity of normal subjects
, 1964 In normal subjects chlorothiazide produced a 21% fall in plasma volume, a 15% decrease in physical working capacity, and an 11% decrease in maximum oxygen consumption. These changes were reversed by intravenous dextran.
Gordon R. Cumming, Rudolph G. Danzinger
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Effects of metolazone in man: Comparison with chlorothiazide
, 1972 Effects of metolazone in man: Comparison with chlorothiazide.The new diuretic agent, metolazone, was investigated to evaluate its mode and sites of action in man.During sustained maximal water diuresis metolazone produced a mean increment in sodium ...
Puschett, Jules B. +1 more
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Clinical Evaluation of Chlorothiazide [PDF]
Circulation, 1959 In the 2 years chlorothiazide has been available, it has been demonstrated to have many of the characteristics of the ideal diuretic agent. It has become an important drug in the treatment of patients with edema and hypertension. Experience has indicated that the side effects and toxic reactions are not severe nor do they prohibit long-term use of the ...
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Clarification of the site of action of chlorothiazide in the rat nephron
, 1975 retics has been attributed to inhibition of sodium reab-sorption in the distal nephron of the kidney. Recent mi-cropuncture studies have shown, however, that chlorothi-azide administration can also inhibit sodium reabsorption in the proximal convolution.
Robert T. Kunau +2 more
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Effects of benzothiadiazine drugs on carbohydrate metabolism [PDF]
, 1965 The administration of chlorothiazide both to man and to rats results in hyperglycemia following a glucose load. Its administration to rats causes a decreased rate of glucose utilization by their adipose tissue in vitro.
Borondy, Paul E., Weller, John M.
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A comprehensive cocrystal screening study of chlorothiazide
, 2017 Cocrystal formation of chlorothiazide (ctz) was screened with a variety of coformers with carboxyl, amide, hydroxyl, sulfonamide, pyridine, amidine, and amine functional groups.
McArdle, P +11 more
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ABSORPTION AND DISPOSITION OF CHLOROTHIAZIDE IN RATS (CAFFEINE).
, 1987 ABSORPTION AND DISPOSITION OF CHLOROTHIAZIDE IN RATS (CAFFEINE)
FUNG-HWA ANN. HSU (7948982)
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Competitive inhibition of renal transport of p-aminohippurate by analogues of chlorothiazide
, 1961 Competitive inhibition of p-aminohippurate (PAH) transport by analogues of chlorothiazide has been demonstrated with slices of rabbit kidney cortex. Although analogues of low pK1 are better inhibitors of PAH transport than are analogues of higher pK1 ...
Alvin Essig
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, 2008 The compounds chlorothiazide and hydrochlorothiazide (crystalline form II) have been studied in their fully hydrogenous forms by powder neutron diffraction on the GEM diffractometer.
Fabbiani, F.P.A. +4 more
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Chlorothiazide effect on feedback-mediated control of glomerular filtration rate
, 1989 We examined the effect of chlorothiazide (CTZ) on the tubuloglomerular (TG) feedback system in anesthetized Sprague-Dawley rats. During infusion of CTZ (0.25 mg.kg body wt-1.min-1) we found that whole kidney glomerular filtration rate (GFR) decreased by
A. E. Persson, F. S. Wright, M. D. Okusa
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