Results 81 to 90 of about 5,213 (178)
The effect of dosage on the bioavailability of chlorothiazide administered in solution
, 1980 Chlorothiazide in solution was administered at four dose levels to three healthy male volunteers under controlled conditions. Excretion data indicated that the drug was poorly absorbed from the gastrointestinal tract.
Owen I Corrigan, Katherine M O'Driscoll
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, 1980 Diazoxide and chlorothiazide (0.1–1.5 mM) had a dose-dependent inhibitory effect on the rate of cAMP and cGMP hydrolysis determined in a 500-g supernatant of rat aorta homogenates; both compounds were weaker inhibitors of cAMP and cGMP hydrolysis than ...
Mariagnes Verosky +2 more
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, 1982 Previous studies have shown that thiazide diuretic agents reverse secondary hyperparathyroidism and reduce circulating 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] and intestinal calcium absorption rates in patients with idiopathic hypercalciuria of the renal-
A. Porat +5 more
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, 2011 Chlorothiazide (CTZ) is a poorly soluble diuretic agent. The aim of the present work was to produce and characterise a potassium salt form of chlorothiazide which has the potential advantages of improved aqueous solubility and potassium supplementation ...
O\u27BRIEN, JOHN EUGENE +5 more
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The Renal Action of Chlorothiazide [PDF]
Proceedings of the Royal Society of Medicine, 1960 openaire +4 more sources
, 1986 The studies systematically evaluated the effect of protein binding on the renal and secretion clearances of furosemide and chlorothiazide. The isolated perfused rat kidney preparation (IPK) was used.
Shih, Ling-Jar
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, 1959 Both chlorothiazide and parenteral mercurial diuretics have an antihypertensive as well as a natriuretic action. Previous observations have suggested that the antihypertensive effect is not due solely to sodium depletion.
M.D Aram V Chobanian +2 more
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, 1989 The solubility of hydrochlorothiazide and Chlorothiazide in milk has been studied. Experiments were carried out at 5, 15, 25, and 37 C on a buffer solution of pH 6.5, a 2.6% solution of casein, bovine skim milk samples, and bovine milk samples with fat ...
Koupparis, M.A. +2 more
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