Results 21 to 30 of about 79,424 (330)

Antipsychotic dose escalation as a trigger for Neuroleptic Malignant Syndrome (NMS): literature review and case series report [PDF]

, 2012
Background: “Neuroleptic malignant syndrome” (NMS) is a potentially fatal idiosyncratic reaction to any medication which affects the central dopaminergic system. Between 0.5% and 1% of patients exposed to antipsychotics develop the condition.
AL Pelonero, BD Berman, D Berardi, D Bereardi, D Heyland, Daniel J Smith, Daniel Martin, F-GB Pajonk, H Itoh, J Ananth, J Delay, J Gill, JF Patterson, JN Trollor, JR Strawn, Julie Langan, K Otani, KL Hall, LF Viejo, LS Friedman, M Dave, MJ Bhanushali, P Adnet, P Sachdev, P Sachdev, PE Keek, PF Buckley, PI Rosebush, PJ Alexander, Polash Shajahan, RJ Gurrera, RJ Gurrera, RW Baker, S Caroff, S Madakasira   +34 more
core   +3 more sources

Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Improved Oral Bioavailability of Chlorpromazine: In Vitro and In Vivo Evaluation

Medicina, 2019
Background and Objectives: Lipid-based self-nanoemulsifying drug delivery systems (SNEDDS) have resurged the eminence of nanoemulsions by modest adjustments and offer many valuable opportunities in drug delivery.
Jeand Baloch, M. Sohail, Hafiz Sarwar, M. H. Kiani, G. Khan, S. Jahan, M. Rafay, M. T. Chaudhry, M. Yasinzai, G. Shahnaz   +9 more
semanticscholar   +1 more source

Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization and regulates receptor replenishment in an agonist-biased manner [PDF]

, 2016
Cannabinoid receptor interacting protein 1a (CRIP1a) is a CB1 receptor (CB1R) distal C-terminus-associated protein that modulates CB1R signaling via G proteins, and CB1R down-regulation but not desensitization (Blume et al.
Bass, Caroline E., Blumes, Lawrence C, Chen, Rong, Howlett, Allyn C., Leone-Kabler, Sandra, Luessen, Deborah J., Lyons, Erica, Marrs, Glenn S., Selley, Dana E.   +8 more
core   +2 more sources

The polarographic determination of chlorpromazine and chlorpromazine sulphoxide

Journal of Pharmacy and Pharmacology, 1966
Abstract Cathodic polarography of solutions containing between 0·1 and 5·0 μg/ml of both chlorpromazine and its sulphoxide enables the sulphoxide to be determined directly. Reductive polarography of the solution after bromination gives an additive wave from which the chlorpromazine is determined by subtraction.
Jean Beresford, G. S. Porter
openaire   +3 more sources

TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243] [PDF]

, 2002
Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all differ.
A Jablensky, B Thornley, CB Joy, Clive E Adams, E Coutinho, Evandro SF Coutinho, Expert Consensus Guideline Group, F Moritz, G Huf, Gisele Huf, HI Kaplan, J Ludbrook, JG Cunnane, LS Pilowsky, M Fenton, M Hotopf, M Wyant, P Armitage, RL Binder, The Royal College of Psychiatrists, VW Berger, Z Atakan   +21 more
core   +3 more sources

Motor deficits in schizophrenia quantified by nonlinear analysis of postural sway. [PDF]

, 2012
Motor dysfunction is a consistently reported but understudied aspect of schizophrenia. Postural sway area was examined in individuals with schizophrenia under four conditions with different amounts of visual and proprioceptive feedback: eyes open or ...
Bolbecker, Amanda R., Forsyth, Jennifer K., Hetrick, William P., Hong, S. Lee, Kent, Jerillyn S., Klaunig, Mallory J., O'Donnell, Brian F.   +6 more
core   +8 more sources

Comparison of Efficacy of Combination Therapy with Chlorpromazine and Olanzapine with Chlorpromazine alone for Treatment of Hiccups in Traumatic Brain Injury Patients- A Randomised Control Trial [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Chlorpromazine belongs to the category of typical antipsychotics or neuroleptics, also known as First-Generation Antipsychotics (FGAs).
Meera Srinivasan, Ghanshyam Yadav, Yashpal Singh, Anurag Sahu, Sarita Kumari, Anup Singh   +5 more
doaj   +1 more source

Internalisation of membrane progesterone receptor-α after treatment with progesterone: Potential involvement of a clathrin-dependent pathway [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund.Internalisation and recycling of seven trans-membrane domain receptors is a critical regulatory event for their signalling.
Dong, J, Foster, H, Karteris, E, Reynolds, A, Stenbeck, G, Thomas, P   +5 more
core   +1 more source

Chlorpromazine Efficiently Treats the Crisis of Pheochromocytoma: Four Case Reports and Literature Review

Frontiers in Cardiovascular Medicine, 2021
Pheochromocytoma multisystem crisis (PMC) is a potentially lethal emergency due to catecholamine secretion. The condition manifests as severe hypertension to intractable cardiogenic shock and has a high mortality rate.
James Jiqi Wang, James Jiqi Wang, Zuowen He, Zuowen He, Yan Yang, Bo Yu, Bo Yu, Hong Wang, Hong Wang, Hu Ding, Hu Ding, Guanglin Cui, Guanglin Cui, Luyun Wang, Luyun Wang, Dao Wen Wang, Dao Wen Wang, Jiangang Jiang, Jiangang Jiang   +18 more
doaj   +1 more source

A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [PDF]

, 2019
Background The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) was first described in 2012 and attracted a great international attention due to multiple healthcare associated outbreaks.
Al-Ali, Anfal Y., Al-Tawfiq, Jaffar A., Momattin, Hisham   +2 more
core   +1 more source