Results 41 to 50 of about 54,869 (285)
The article presents the development of artificial lipid droplets (aLDs) as biomimetic nanocarriers to enhance intramuscular fat (IMF) content in pigs. These aLDs, loaded with oleic acid, significantly increase IMF by up to 35% in muscle tissues without adverse side effects. This innovative approach improves pork quality by enhancing marbling, offering
Pengxiang Zhao+8 more
wiley +1 more source
AAV2.7m8 serotype combined with the gfaABC1D promoter targets infection of supporting cells (SCs). AAV2.7m8‐gfaABC1D‐Gjb2 administration to mice results in excessive immune responses. The combination of AAV2.7m8‐gfaABC1D‐Gjb2 with dexamethasone (DEX) shows a synergistic effect and enhances the gene therapy effect in a conditional Cx26 null mice model ...
Xiaohui Wang+8 more
wiley +1 more source
Current perspectives on chlorpromazine equivalents: Comparing apples and oranges!
1. Bindu A, Rao TS, Ashok NC, Prabhakar AK, Manickam LS. Identifying the ‘mentally disabled’ in the community: How much more is to be imparted to the internees in training? Indian J Psychiatry 2011;53:53-6. 2. 58th NSSO Report.
Vijay Danivas, G. Venkatasubramanian
semanticscholar +1 more source
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu+6 more
wiley +1 more source
A multifunctional AuNR@SiO2@MnO2@ DNA prodrugs (ASMD) nanodrug is designed to establish an in situ and real‐time photoacoustic (PA)/magnetic resonance (MR)/fluorescence (FL) multi‐modality imaging guided orderly photothermal therapy (PTT)/chemodynamic therapy (CDT)/gene therapy (GT) triple‐therapy of tumor.
Chaoyi Yang+10 more
wiley +1 more source
The elasticity of lipid nanoparticles (LNPs) is essential to their tumor‐targeting efficacy. Softer LNPs penetrate tumors faster and more easily enter into softer cancer cells, while stiffer LNPs show prolonged retention in stiffer tumors. The presence of protumoral M2 macrophages enhances the LNPs uptake into stiffer cancer cells, facilitating ...
Eunhee Lee+5 more
wiley +1 more source
Objective: This study aimed to compare the efficacy of propofol and chlorpromazine in managing acute migraine attacks and to contribute to optimizing the treatment of patients with migraine in the ED.Methods: This prospective, randomized observational ...
Özlem Güneysel, Sarper Sağlam
doaj +1 more source
THE EFFECT OF LITHIUM ON ACUTE TOXICITY OF CHLORPROMAZINE IN MICE [PDF]
The effects of chronic administration of lithium, on acute toxicity of chlorpromazine (CPZ) in male albino mice was studied and the LDSO values were determined from dose-probit curves.
Dehpour, A.R., Samini M. Rahimsalehi, V.
doaj
Seis cães, pesando 17,9kg (±3,9), foram anestesiados em duas ocasiões, com intervalo de sete dias, obedecendo estudo cego. A indução e a manutenção anestésica foram realizadas com isoflurano em ventilação mecânica.
Fabíola Niederauer Flôres+6 more
doaj +1 more source
Background: Opioids are useful in the management of vaso-occlusive crisis among Sickle Cell Disease patients; however, there is a need to search for drugs that can ameliorate the withdrawal symptoms without causing further dependence.
JOSHUA FALADE+6 more
doaj +1 more source