Results 41 to 50 of about 51,092 (216)
Advanced Science, EarlyView.Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li +15 more
wiley +1 more source
Current perspectives on chlorpromazine equivalents: Comparing apples and oranges!
Indian Journal of Psychiatry, 2013 1. Bindu A, Rao TS, Ashok NC, Prabhakar AK, Manickam LS. Identifying the ‘mentally disabled’ in the community: How much more is to be imparted to the internees in training? Indian J Psychiatry 2011;53:53-6. 2. 58th NSSO Report.
Vijay Danivas, G. Venkatasubramanian
semanticscholar +1 more source
Advanced Science, EarlyView.This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma +16 more
wiley +1 more source
Atatürk Üniversitesi Tıp Fakültesi Cerrahi Tıp Bilimleri DergisiObjective: This study aimed to compare the efficacy of propofol and chlorpromazine in managing acute migraine attacks and to contribute to optimizing the treatment of patients with migraine in the ED.Methods: This prospective, randomized observational ...
Özlem Güneysel, Sarper Sağlam
doaj +1 more source
Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs
Advanced NanoBiomed Research, EarlyView.Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna +9 more
wiley +1 more source
Agmatine prevents acute chlorpromazine-induced neurotoxicity in rats [PDF]
Arhiv za farmaciju, 2015 The present study was directed to potentially beneficial effects of agmatine (AGM) on oxidative/nitrosative stress development in selective vulnerable brain regions during chlorpromazine (HPZ) treatment in rats.
Dejanović Bratislav +5 more
doaj +1 more source
Drug poisonings following bariatric surgery: Case series report
British Journal of Clinical Pharmacology, EarlyView.Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari +3 more
wiley +1 more source
Arquivo Brasileiro de Medicina Veterinária e ZootecniaRenal ischemia can be associated with some urological procedures, such as renovascular surgery or kidney transplantation, that are often followed by acute renal failure.
L.B. Menezes +9 more
doaj +1 more source
BMEMat, EarlyView.A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie +12 more
wiley +1 more source
ChemistryOpen, EarlyView.The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges +15 more
wiley +1 more source