Results 11 to 20 of about 4,931 (189)
Two Patients With Extremely Long Type 1 Diabetes Duration With Very Few Complications and Remaining Insulin Secretion. [PDF]
ABSTRACT We present two patients with > 80 years with type 1 diabetes (T1D), but with minor complications. Their history and risk factors are characterized as are factors conferring resilience against angiopathy. Amazingly, both had clearly detectable C‐peptide.
Sjöholm Å, Espes D.
europepmc +2 more sources
Roux-en-Y gastric bypass surgery decreases intestinal aryl hydrocarbon receptor signaling in male mice. [PDF]
Abstract The impact of Roux‐en‐Y gastric bypass (RYGB) on indole metabolism and AhR signaling is poorly understood. Therefore, we tested the hypothesis that RYGB changes the indole metabolite profile in the gut, leading to changes in AhR signaling. To test this hypothesis, we developed a mouse model of RYGB that recapitulates the human procedure. Given
Wang A +4 more
europepmc +2 more sources
Simultaneous Quantification of Antidiabetic Agents in Human Plasma by a UPLC-QToF-MS Method. [PDF]
An ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry method for the simultaneous quantification of chlorpropamide, glibenclamide, gliclazide, glimepiride, metformin, nateglinide, pioglitazone, rosiglitazone, and ...
Mariana Millan Fachi +4 more
doaj +1 more source
Association between insulin resistance and prostate volume: A 4-year analysis from the Reduction by Dutasteride of Prostate Cancer (REDUCE) Trial. [PDF]
Abstract Objectives Most, but not all studies, suggest insulin resistance is associated with benign prostatic hyperplasia, but its impact on prostate volume (PV) changes over time remains unclear. We examined whether higher insulin resistance, measured by Homeostatic Model Assessment of Insulin Resistance (HOMA‐IR), is associated with larger PV and ...
Daniels JP +6 more
europepmc +2 more sources
A sensitive, simple, and fast liquid chromatography–tandem mass spectrometry (LC–MS/MS) bioanalytical method was developed to determine remifentanil in human plasma and prevent its instability by esterases during quantification.
Soon Uk Chae +6 more
doaj +1 more source
The Role of Vasopressin V2 Receptor in Drug-Induced Hyponatremia
Hyponatremia is frequently encountered in clinical practice and usually induced by renal water retention. Many medications are considered to be among the various causes of hyponatremia, because they either stimulate the release of arginine vasopressin ...
Sua Kim +3 more
doaj +1 more source
The antidiabetic effect of chloroform-methanol extract of Abrus precatorious seed, was studied in alloxan diabetic rabbits. The effect was compared to that of chlorpropamide - a known antidiabetic drug in the class of sulphonylurea and a control group ...
CC Monago, EO Alumanah
doaj +1 more source
Where do sulphonylureas fit in the type 2 diabetes guidelines?
Sulphonylureas act by binding to sulphonylurea receptors and stimulating insulin secretion from pancreatic beta cells. This class of oral hypoglycaemic agents is still widely used in the management of type 2 diabetes in patients where lifestyle changes ...
Gail Mkele
doaj +1 more source
We identified populations that evolved resistance to acetyl CoA carboxylase (ACCase) inhibitors, generated a draft genome, elucidated the phylogenetic relationship with other important grass species, performed an extensive characterization of the resistance mechanisms, and developed a genetic assay for rapid resistance identification of Chloris virgata
Luiz Augusto Inojosa Ferreira +3 more
wiley +1 more source
Autoimmune Complications of Lymphoproliferative Diseases. [PDF]
ABSTRACT Peripheral autoimmune cytopenias may complicate a fraction of lymphoproliferative disorders (LPD), particularly chronic lymphocytic leukemia, non‐Hodgkin B‐cell lymphomas, angioimmunoblastic T‐cell lymphoma and large granular lymphocytic leukemia.
Barcellini W, Fattizzo B.
europepmc +2 more sources

