Transcutaneous permeation enhancer complex for polymer-based transdermal patches
Selecting a permeation enhancer complex (PEC) for inclusion in a matrix-type transdermal patch (TP) is a primary task in creating a new dosage form with percutaneous administration.
E. G. Kuznetsova +4 more
doaj +1 more source
Role of oral hypoglycemic agents in the management of type 2 diabetes mellitus during Ramadan
It is obligatory for all adult Muslims to observe fast during the holy month of Ramadan, but sick individuals including those with diabetes mellitus are exempted from the duty of fasting.
Mir Iftikhar Bashir +8 more
doaj +1 more source
The Polymorphic Phase Transformations in the Chlorpropamide under Pressure
The crystal structure and vibrational spectra of the chlorpropamide have been studied by means of the X-ray diffraction andRaman spectroscopy at pressures up to 24.6 and 4.4 GPa, respectively.
Nawrocik, Wojciech +7 more
core +1 more source
Rapid high performance liquid chromatographic determination of chlorpropamide in human plasma [PDF]
Samples were extracted with dichloromethane and the organic layer evaporated to dryness. The residue was dissolved in methanol, and 25 ìl aliquot injected onto the column. Tolbutamide was used as theinternal standard for chlorpropamide.
Odunola, MTB +3 more
core +1 more source
Spatial and Temporal Visualization of Polymorphic Transformations in Pharmaceutical Tablets
X‐ray Diffraction Computed Tomography (XRD‐CT) has been used to reveal pressure‐induced phase transformations in pharmaceutical tablets of glycolide as a function of compaction pressure. Temporal analysis of the tablets, and subsequent identification using electron diffraction, revealed a hydrolysis reaction occurred on storage of the tablets.
Julia Gasol‐Cardona +9 more
wiley +2 more sources
Comparison of the inhibitory effect of ATP-dependent K+ channel blockers glibenclamide and chlorpropamide, on diazoxide-induced relaxation of rat ileum [PDF]
Objective: This study was conducted to compare the potential inhibitory effect of ATP-dependent K+ channel blockers, glibenclamide and chlorpropamide on diazoxide-induced relaxation of isolated rat ileum.
J. Mohiti, A. Babaei
core +1 more source
SGLT‐2 Inhibitors are Associated With a Lower Risk of Multiple Myeloma
ABSTRACT Aims We aimed to investigate drug response of sodium‐glucose transport protein‐2 inhibitors (SGLT2i) in multiple myeloma (MM), as SGLT2i have potential favorable effects on conditions related to MM. Methods We conducted a pharmacoepidemiologic study with a US nationwide health insurance claim data using Cox models to investigate the ...
Enze Liu +6 more
wiley +1 more source
A spectrophotometric study of chlorpropamide is described. The method is based on the charge-transfer complexation between chlorpropamide (the n-electron donor) with chloranilic acid (the p-acceptor) to form a violet coloured complex having absorption ...
C. J. Mbah, N. H. Okorie
core +1 more source
The assay and stability of chlorpropamide in solid dispersion with urea
Thin layer chromatography followed by reflectance densitometry has been used to evaluate the stability of chlorpropamide-urea during the fusion process.
James L Ford +2 more
core +1 more source
Gas-liquid chromatographic estimation of tolbutamide and chlorpropamide in plasma
An improved method for the gas-liquid chromatographic estimation of tolbutamide and chlorpropamide in plasma is described. The drugs are extracted into toluene, back-extracted into alkali and methylated with dimethylsulphate.
D R REDMAN, L F PRESCOTT
core +1 more source

