Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties [PDF]
, 2009 Purpose. The micronization using milling process to enhance dissolution rate is extremely inefficient due to a high energy input, and disruptions in the crystal lattice which can cause physical or chemical instability.
Mostafavi, Seyed Abolfazl +3 more
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Spatial and Temporal Visualization of Polymorphic Transformations in Pharmaceutical Tablets
Angewandte Chemie, Volume 137, Issue 2, January 10, 2025.X‐ray Diffraction Computed Tomography (XRD‐CT) has been used to reveal pressure‐induced phase transformations in pharmaceutical tablets of glycolide as a function of compaction pressure. Temporal analysis of the tablets, and subsequent identification using electron diffraction, revealed a hydrolysis reaction occurred on storage of the tablets.
Julia Gasol‐Cardona +9 more
wiley +2 more sources
Role of oral hypoglycemic agents in the management of type 2 diabetes mellitus during Ramadan
Indian Journal of Endocrinology and Metabolism, 2012 It is obligatory for all adult Muslims to observe fast during the holy month of Ramadan, but sick individuals including those with diabetes mellitus are exempted from the duty of fasting.
Mir Iftikhar Bashir +8 more
doaj +1 more source
Transcutaneous permeation enhancer complex for polymer-based transdermal patches
Вестник трансплантологии и искусственных органовSelecting a permeation enhancer complex (PEC) for inclusion in a matrix-type transdermal patch (TP) is a primary task in creating a new dosage form with percutaneous administration.
E. G. Kuznetsova +4 more
doaj +1 more source
Chlorpropamide-induced thrombocytopenia [PDF]
Postgraduate Medical Journal, 1977 Summary Thrombocytopenia is a rare complication of chlorpropamide therapy. An immunological mechanism is generally held responsible, but has never previously been proved. In the present case the existence of such a mechanism has been established.
D J, Cunliffe, D W, Gorst, H M, Palmer
openaire +2 more sources
Are concomitant treatments confounding factors in randomized controlled trials on intensive blood-glucose control in type 2 diabetes? a systematic review [PDF]
, 2013 International audienceBackgroundOpen-label, randomized controlled trials (RCTs) are subject to observer bias. If patient management is conducted without blinding, a difference between groups may be explained by other factors than study treatment.
Bejan-Angoulvant, Theodora +7 more
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Comparative study of the hypoglycemic and biochemical effects of Catharanthus roseus (Linn) g. apocynaceae (Madagascar periwinkle) and chlorpropamide (diabenese) on alloxan-induced diabetic rats [PDF]
, 2005 The effect of the aqueous extracts of Catharanthus roseus and chlorpropamide (Diabenese) on the levels of serum cholesterol, total protein, lipid peroxidation, blood glucose and liver enzymes were compared in alloxan-induced diabetic rats.
Iweala, E. E. J., Okeke, C. U.
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Acta Crystallographica Section B, EarlyView.The polymorphic behaviour of the three forms of artemisinin was investigated using single‐crystal X‐ray diffraction in a diamond anvil cell, with notable observation of a pressure‐induced phase transition from form (II) to form (III).Artemisinin (ART) is mainly used for the treatment of malaria and exhibits polymorphism with two known crystalline forms.
Banaz Fetah +4 more
wiley +1 more source
Treatment of Diabetes With Oral Hypoglycemic Drugs [PDF]
, 1966 Oral hypoglycemic drugs now available are of two types. The biguanides, of which phenformin (DBI) is the only one available, increase glucose utilization by muscles.
Moss, James M.
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Introductory lecture: Mechanochemistry, a versatile synthesis strategy for new materials. [PDF]
, 2014 Mechanochemistry deals with reactions induced by the input of mechanical energy - for example by impacts within a vibratory ball mill. The technique has a long history with significant contributions from Ostwald, Carey Lea and, notably, Faraday ...
Eddleston, Mark D, Jones, William
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