Results 41 to 50 of about 2,658 (141)

Current type 2 diabetes guidelines: Individualized treatment and how to make the most of metformin

open access: yesDiabetes, Obesity and Metabolism, Volume 26, Issue S3, Page 55-74, August 2024.
Abstract Evidence‐based guidelines provide the premise for the delivery of quality care to preserve health and prevent disabilities and premature death. The systematic gathering of observational, mechanistic and experimental data contributes to the hierarchy of evidence used to guide clinical practice. In the field of diabetes, metformin was discovered
Juliana C. N. Chan   +3 more
wiley   +1 more source

Prevalence of potentially inappropriate medications among newly treated patients with type 2 diabetes in UK primary care

open access: yesBritish Journal of Clinical Pharmacology, Volume 90, Issue 6, Page 1376-1394, June 2024.
Abstract Aims The aim of this study was to estimate the prevalence of potentially inappropriate prescriptions (PIPs) in patients starting their first noninsulin antidiabetic treatment (NIAD) using two explicit process measures of the appropriateness of prescribing in UK primary care, stratified by age and polypharmacy status.
Maria Luisa Faquetti   +4 more
wiley   +1 more source

Solubility and Stability of Carvedilol in Deep Eutectic Solvents: A Step Towards a Sustainable Pharmaceutical Formulation in the Liquid State

open access: yesChemistrySelect, Volume 9, Issue 11, March 18, 2024.
This study investigates the use of aqueous eutectic mixtures to enhance the solubility of carvedilol, a drug with low solubility and bioavailability. It was found that mixtures of citric acid and choline chloride increased the maximum solubility. Additionally, the stability of carvedilol in these mixtures was demonstrated.
Laura Lomba   +4 more
wiley   +1 more source

Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy

open access: yesAdvanced Science, Volume 11, Issue 2, January 12, 2024.
This study reveals that the mitochondrial chaperone TRAP1 is vital for stabilizing HIF1α, a key transcription factor in pathologic microvascular changes in ischemic retinopathies. Therefore, inhibiting TRAP1 genetically or pharmacologically alleviates retinal vascular pathologies by inducing HIF1α proteolytic degradation, indicating that TRAP1 can be a
So‐Yeon Kim   +10 more
wiley   +1 more source

Proposal for a systematic naming convention for liamocins

open access: yes
Journal of Surfactants and Detergents, Volume 27, Issue 3, Page 459-461, May 2024.
Till Tiso   +6 more
wiley   +1 more source

Influência do tratamento com metformina sobre a tolerância à glicose induzida por corticosteróides em ratos Wistar = Influence of metformin treatment on glucose tolerance induced by corticosteroid administration in rats Wistar

open access: yesActa Scientiarum. Health Sciences, 2006
Corticóides induzem um estado de intolerância à glicose, resistência à insulina e hiperglicemia. Este trabalho teve por objetivo avaliar a participação de corticosteróides endógenos sobre a hiperglicemia aguda em modelo experimental de intolerância à ...
Fábio César Gonçalves   +7 more
doaj  

A lichenoid drug eruption secondary to pyridostigmine. [PDF]

open access: yesJAAD Case Rep
Grechin C, Munteanu T, Gale J.
europepmc   +1 more source

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