Results 41 to 50 of about 3,364 (147)

Solubility of Tolbutamide and Chlorpropamide in Supercritical Carbon Dioxide

, 2018
Tolbutamide and chlorpropamide are oral hypoglycemic drugs that are used to treat diabetic patients. In the context of employing these drugs in green pharmaceutical applications that make use of supercritical fluids, the solubility of tolbutamide and ...
Manna, Luigi, Mauro Banchero (4923640), Luigi Manna (4923637), Luigi Manna, Banchero, Mauro, Mauro Banchero   +5 more
core   +1 more source

Metabolic bariatric surgery is associated with reduced adverse hepatic and extrahepatic outcomes, and lower all‐cause mortality, in patients with steatotic liver disease

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 174-185, January 2026.
Abstract Aim Metabolic bariatric surgery (MBS) improves histological endpoints in steatotic liver disease (SLD), but data on longer‐term clinical outcomes in this population are scarce. Here, we assessed the impact of MBS on hepatic and extrahepatic morbidity and mortality in individuals with SLD.
Weronika Stupalkowska, Alexander Henney, Eric G. Sheu, Uazman Alam, Daniel J. Cuthbertson   +4 more
wiley   +1 more source

Evaluation of Potentially Inappropriate Medication Use in Patients Aged ≥ 80 Years With Atrial Fibrillation According to STOPP Criteria Version 3 and 2023 Beers Criteria

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
What is Known and Objective The presence of potentially inappropriate medications (PIMs) is associated with drug‐related harmful effects, including adverse drug events, elevated rates of hospital readmissions, and higher mortality rates. Patients aged ≥ 80 years with atrial fibrillation (AF) often present with multiple comorbidities and polypharmacy ...
Ying Bai, Jianqi Wang, Guangyao Li, Zhen Zhou, Anjali Chauhan   +4 more
wiley   +1 more source

Therapeutic challenge: Unusual coexistence of idiopathic central diabetes insipidus and diabetes mellitus in a male with vitiligo

Caspian Journal of Internal Medicine, 2021
Background: Idiopathic central diabetes insipidus (DI) is a rare endocrine disorder that results from total or partial deficiency of vasopressin secretion.
Diego Moreno Marreros, Marcio José Concepción Zavaleta, Eilhart Jorge Garxia Villasante, Esteban Alberto Plasencia Dueñas, Sofia Ildefonso Najarro, José Carrion Rojas, Carmen Luisa Achahui Acurio   +6 more
doaj  

Association between insulin resistance and prostate volume: A 4‐year analysis from the Reduction by Dutasteride of Prostate Cancer (REDUCE) Trial

BJUI Compass, Volume 6, Issue 9, September 2025.
Abstract Objectives Most, but not all studies, suggest insulin resistance is associated with benign prostatic hyperplasia, but its impact on prostate volume (PV) changes over time remains unclear. We examined whether higher insulin resistance, measured by Homeostatic Model Assessment of Insulin Resistance (HOMA‐IR), is associated with larger PV and ...
James P. Daniels, Alexander Hernández‐Tirado, James Mirocha, Renning Zheng, Jordan Palmer, Daniel Moreira, Stephen J. Freedland   +6 more
wiley   +1 more source

Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity under high glucose conditions

Cardiovascular Diabetology, 2007
Background Inhibition of vascular smooth muscle cell (vSMC) proliferation by oral anti-hyperglycemic agents may have a role to play in the amelioration of vascular disease in diabetes.
de Dios Stephanie T, Osman Narin, Little Peter J, Cemerlang Nelly, Ballinger Mandy, Nigro Julie   +5 more
doaj   +1 more source

Roux‐en‐Y gastric bypass surgery decreases intestinal aryl hydrocarbon receptor signaling in male mice

Physiological Reports, Volume 13, Issue 16, August 2025.
Abstract The impact of Roux‐en‐Y gastric bypass (RYGB) on indole metabolism and AhR signaling is poorly understood. Therefore, we tested the hypothesis that RYGB changes the indole metabolite profile in the gut, leading to changes in AhR signaling. To test this hypothesis, we developed a mouse model of RYGB that recapitulates the human procedure. Given
Annie Wang, Madelynn E. Agabao‐Tucker, Michael L. Goodson, Allison K. Ehrlich, Bethany P. Cummings   +4 more
wiley   +1 more source

Effects of Hot Air Drying on the Nutritional and Phytochemical Composition of Radish (Raphanus sativus L.) Microgreens

Journal of Food Science, Volume 90, Issue 7, July 2025.
ABSTRACT Cruciferous microgreens are recognized for their high content of phytochemicals, particularly glucosinolates. Their high moisture content and water activity make them highly perishable after harvest and highlight the need for effective preservation methods that maintain their nutritional quality.
Marjorie J. Jauregui, Ezekiel R. Warren, Francesco Di Gioia, Misha T. Kwasniewski, Joshua D. Lambert   +4 more
wiley   +1 more source

Chlorpropamide Inhibition Of Excision Repair And Postreplication Repair Of Ultraviolet Damage In Chinese Hamster Ovary Cells

, 1980
Chlorpropamide, an oral hypoglycemic agent, was tested for effects on excision repair and postreplication repair of ultraviolet (UV) damage of DNA in CHO-K1 cells. The technique used to measure excision repair involved isopycnic centrifugation of density-
Brown, Roger F.
core   +1 more source

Autoimmune Complications of Lymphoproliferative Diseases

Hematological Oncology, Volume 43, Issue S2, June 2025.
ABSTRACT Peripheral autoimmune cytopenias may complicate a fraction of lymphoproliferative disorders (LPD), particularly chronic lymphocytic leukemia, non‐Hodgkin B‐cell lymphomas, angioimmunoblastic T‐cell lymphoma and large granular lymphocytic leukemia.
Wilma Barcellini, Bruno Fattizzo
wiley   +1 more source