Results 41 to 50 of about 2,658 (141)
Current type 2 diabetes guidelines: Individualized treatment and how to make the most of metformin
Abstract Evidence‐based guidelines provide the premise for the delivery of quality care to preserve health and prevent disabilities and premature death. The systematic gathering of observational, mechanistic and experimental data contributes to the hierarchy of evidence used to guide clinical practice. In the field of diabetes, metformin was discovered
Juliana C. N. Chan +3 more
wiley +1 more source
Abstract Aims The aim of this study was to estimate the prevalence of potentially inappropriate prescriptions (PIPs) in patients starting their first noninsulin antidiabetic treatment (NIAD) using two explicit process measures of the appropriateness of prescribing in UK primary care, stratified by age and polypharmacy status.
Maria Luisa Faquetti +4 more
wiley +1 more source
This study investigates the use of aqueous eutectic mixtures to enhance the solubility of carvedilol, a drug with low solubility and bioavailability. It was found that mixtures of citric acid and choline chloride increased the maximum solubility. Additionally, the stability of carvedilol in these mixtures was demonstrated.
Laura Lomba +4 more
wiley +1 more source
Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy
This study reveals that the mitochondrial chaperone TRAP1 is vital for stabilizing HIF1α, a key transcription factor in pathologic microvascular changes in ischemic retinopathies. Therefore, inhibiting TRAP1 genetically or pharmacologically alleviates retinal vascular pathologies by inducing HIF1α proteolytic degradation, indicating that TRAP1 can be a
So‐Yeon Kim +10 more
wiley +1 more source
Proposal for a systematic naming convention for liamocins
Journal of Surfactants and Detergents, Volume 27, Issue 3, Page 459-461, May 2024.
Till Tiso +6 more
wiley +1 more source
Corticóides induzem um estado de intolerância à glicose, resistência à insulina e hiperglicemia. Este trabalho teve por objetivo avaliar a participação de corticosteróides endógenos sobre a hiperglicemia aguda em modelo experimental de intolerância à ...
Fábio César Gonçalves +7 more
doaj
Kinetic effects yield different results on the timescales of laboratory and synchrotron high-pressure experiments. [PDF]
Haines J.
europepmc +1 more source
A lichenoid drug eruption secondary to pyridostigmine. [PDF]
Grechin C, Munteanu T, Gale J.
europepmc +1 more source

