British Journal of Clinical Pharmacology, Volume 90, Issue 6, Page 1376-1394, June 2024.Abstract Aims The aim of this study was to estimate the prevalence of potentially inappropriate prescriptions (PIPs) in patients starting their first noninsulin antidiabetic treatment (NIAD) using two explicit process measures of the appropriateness of prescribing in UK primary care, stratified by age and polypharmacy status.
Maria Luisa Faquetti +4 more
wiley +1 more source
Efeitos imunomoduladores dos hipoglicemiantes orais em cultura de linfócitos de pacientes com diabetes mellitus do tipo 2. [PDF]
, 2005 A clorpropamida é uma droga hipoglicemiante que atua bloqueando os canais de K+ ATP-dependentes, provocando com isto um aumento na liberação de insulina.
Mello, Karina Faccio
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Comparative Effects of Three Herbs and Standard Hypoglycaemic Agents on Blood Glucose in Normoglycaemic, Hyperglycaemic and Alloxan-Induced Diabetic Male Rats [PDF]
, 2010 Background: The prevalence of diabetes mellitus has risen exponentially in the last decade and an increasing number of people are using herbal supplements.
Adesiyun, AE +3 more
core +2 more sources
بررسی اثرات عروقی تجويز مزمن 2 داروی سولفونيل اوره از نسل اول(کلرپروپاميد) و نسل دوم(گلی‌بن‌کلاميد) بر عمل‌کرد آئورت سينه‌ای موش صحرايی سالم [PDF]
, 2004 داروهای سولفونيل اوره به فراوانی در درمان بيماران مبتلا به ديابت تيپ دو مصرف می‌شود. گزارش‌های ضد و نقيضی در مورد ايجاد عوارض قلبی ـ عروقی توسط اين داروها وجود دارد.
ايزدپناه, اسماعیل +3 more
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ChemistrySelect, Volume 9, Issue 11, March 18, 2024.This study investigates the use of aqueous eutectic mixtures to enhance the solubility of carvedilol, a drug with low solubility and bioavailability. It was found that mixtures of citric acid and choline chloride increased the maximum solubility. Additionally, the stability of carvedilol in these mixtures was demonstrated.
Laura Lomba +4 more
wiley +1 more source
Anti-diabetic drugs in the private and public sector in Dar es Salaam, Tanzania [PDF]
, 2010 Objectives: To compare availability, cost, affordability and sources of anti-diabetic drugs between private and public health facilities in Dar es Salaam, Tanzania. Design: Cross sectional descriptive study.Setting: Diabetic clinics in private and public
Justin-Temu, M +4 more
core +2 more sources
Roles of chlorpropamide, alcohol and acetaldehyde in determining the chlorpropamide-alcohol flush [PDF]
Diabetologia, 1984 The value and reproducibility of the chlorpropamide-alcohol flush (CPAF) have been questioned, and objective measures of the test are required. Recording of facial skin temperature, measurement of chlorpropamide, ethanol and acetaldehyde concentrations have been proposed for this purpose.
R. Huupponen +4 more
openaire +3 more sources
Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy
Advanced Science, Volume 11, Issue 2, January 12, 2024.This study reveals that the mitochondrial chaperone TRAP1 is vital for stabilizing HIF1α, a key transcription factor in pathologic microvascular changes in ischemic retinopathies. Therefore, inhibiting TRAP1 genetically or pharmacologically alleviates retinal vascular pathologies by inducing HIF1α proteolytic degradation, indicating that TRAP1 can be a
So‐Yeon Kim +10 more
wiley +1 more source
Effects of Cataranthus roseus on Electrolyte Derangement Induced by Chlorpropamide (Diabinese)R on Normoglycemic Albino Wistar Rat [PDF]
, 2009 This study was designed to evaluate the efficacy (or otherwise) of Cataranthus roseus extract in ameliorating electrolyte imbalance following treatment with anti-diabetic drug chlorpropamide (Diabinese)R.
Essien, AD +3 more
core +2 more sources
Oral Hypoglycemic Agents [PDF]
, 1977 In conclusion, comment is made on the findings of the University Group Diabetes Program (UGDP). The purpose of the UGDP was to determine whether or not control of blood glucose levels would help to prevent or delay vascular disease in non-insulin ...
Rifkin, Harold
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