Results 51 to 60 of about 5,936 (212)

Solubility and Stability of Carvedilol in Deep Eutectic Solvents: A Step Towards a Sustainable Pharmaceutical Formulation in the Liquid State

ChemistrySelect, Volume 9, Issue 11, March 18, 2024.
This study investigates the use of aqueous eutectic mixtures to enhance the solubility of carvedilol, a drug with low solubility and bioavailability. It was found that mixtures of citric acid and choline chloride increased the maximum solubility. Additionally, the stability of carvedilol in these mixtures was demonstrated.
Laura Lomba, Alejandra Polo, Nuria Martínez, Julia Alejandre, Beatriz Giner   +4 more
wiley   +1 more source

Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy

Advanced Science, Volume 11, Issue 2, January 12, 2024.
This study reveals that the mitochondrial chaperone TRAP1 is vital for stabilizing HIF1α, a key transcription factor in pathologic microvascular changes in ischemic retinopathies. Therefore, inhibiting TRAP1 genetically or pharmacologically alleviates retinal vascular pathologies by inducing HIF1α proteolytic degradation, indicating that TRAP1 can be a
So‐Yeon Kim, Nam Gu Yoon, Jin Young Im, Ji Hye Lee, Juhee Kim, Yujin Jeon, Young Jae Choi, Jong‐Hwa Lee, Akiyoshi Uemura, Dong Ho Park, Byoung Heon Kang   +10 more
wiley   +1 more source

Chlorpropamide-alcohol flushing, aldehyde dehydrogenase activity, and diabetic complications. [PDF]

, 1982
Rowan Hillson, Robin Smith, Chittaranjan S. Yajnik, T. D. R. Hockaday, H.‐H. TING, J Crabbé   +5 more
openalex   +3 more sources

Hormonal and metabolic effects of chlorpropamide, glibenclamide and placebo in a cross-over study in diabetics not controlled by diet alone [PDF]

, 1981
Peter H. Sönksen, C. Lowy, J. R. Perkins, Tim West   +3 more
openalex   +3 more sources

Proposal for a systematic naming convention for liamocins

Journal of Surfactants and Detergents, Volume 27, Issue 3, Page 459-461, May 2024.
Till Tiso, Gina Welsing, Anna Lipphardt, Daniel F. Sauer, Zhenming Chi, Lars M. Blank, Heiko Hayen   +6 more
wiley   +1 more source

Influência do tratamento com metformina sobre a tolerância à glicose induzida por corticosteróides em ratos Wistar = Influence of metformin treatment on glucose tolerance induced by corticosteroid administration in rats Wistar

Acta Scientiarum. Health Sciences, 2006
Corticóides induzem um estado de intolerância à glicose, resistência à insulina e hiperglicemia. Este trabalho teve por objetivo avaliar a participação de corticosteróides endógenos sobre a hiperglicemia aguda em modelo experimental de intolerância à ...
Fábio César Gonçalves, Fernando Antonio Bersani-Amado, Silmara Baroni, Juarez de Souza, Carlos Alexandre Molena Fernandes, Rui Gonçalves Marques Elias, Gustavo Schmidt, Roberto Kenji Nakamura Cuman   +7 more
doaj  

The influence of chlorpropamide pre-treatment on insulin and growth hormone release after arginine [PDF]

, 1967
Lamar Riggs, D. Rabinowitz, T J Merimée
openalex   +1 more source

The effect of chloroquine on the pharmacokinetics of chlorpropamide in human volunteers [PDF]

, 2011
U. Danlami
openalex   +1 more source

Blood concentrations of acetaldehyde during chlorpropamide-alcohol flush. [PDF]

, 1981
A H Barnett, Carlos Gonzalez-Auvert, D A Pyke, J B Saunders, R. Williams, C J Dickenson, M. D. Rawlins   +6 more
openalex   +1 more source

Prevalence of chlorpropamide alcohol flushing [PDF]

, 1984
S. Ng Tang Fui, Henry L. Keen, R. J. Jarrett   +2 more
openalex   +1 more source