Results 31 to 40 of about 659,838 (261)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Gonioctena (Asiphytodecta) mausonensis Cho & Borowiec 2016

open access: yes, 2016
Gonioctena (Asiphytodecta) mausonensis Cho & Borowiec, 2016 (Figs 4, 9, 25–26, 29) Gonioctena (Asiphytodecta) flavoplagiata (partim): YANG et al. (2014): 384 (taxonomy, misidentification); YANG et al.
Cho, Hee-Wook, Borowiec, Lech
core   +1 more source

CHO-K1, COS7, and HEK293 cells express PAR1 and PAR2 receptors.

open access: yes, 2020
A. CHO-K1, COS7, and HEK293 cells naturally express high levels of PAR1 and PAR2 mRNA but express little or no PAR3 and PAR4 mRNA. qPCR analysis was used to quantify the mRNA expression.
Chester Kuei (1660933)   +10 more
core   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO-8

open access: yes, 2011
Copyright information:Taken from "Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO"http://www.biomedcentral.com/1471-2210/7/8BMC Pharmacology 2007;7():8-8.Published online 27 Jun 2007PMCID:PMC1931592.or ...
Satoshi Sunaga (77404)   +7 more
core   +1 more source

Mucocutaneous Disease Activity and Damage Accrual in Systemic Lupus Erythematosus: Analyses From the Asia‐Pacific Lupus Collaboration Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective This research article aims to describe the prevalence, associations, and health‐related quality of life (HRQoL) impact of mucocutaneous features of systemic lupus erythematosus (SLE). Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analyzed (2013–2021).
Amanda M. Saracino   +42 more
wiley   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa   +3 more
wiley   +1 more source

Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO-0

open access: yes, 2011
Copyright information:Taken from "Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO"http://www.biomedcentral.com/1471-2210/7/8BMC Pharmacology 2007;7():8-8.Published online 27 Jun 2007PMCID:PMC1931592.or ...
Satoshi Sunaga (77404)   +7 more
core   +1 more source

Short‐Term Response to Biologic Therapy in Psoriatic Arthritis Is Not Influenced by Disease Duration at Initiation of Therapy

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to determine whether the short‐term response to biologics in biologic‐naive psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods Patients with PsA who started on biologic therapy from the year 2000 to 2025 were included for analysis.
Sung Min Cho   +4 more
wiley   +1 more source

Four-week inhalation toxicity, mutagenicity and immunotoxicity studies of Keum-Yeon-Cho (NosmoQ), tobacco substitute composition, in mice

open access: yes, 2003
Safety of Kcum-Yeon-Cho (NosmoQ), a tobacco substitute composition, was evaluated in terms of acute- and 4,weeks repeated-inhalation toxicity, mutagenicity, and immunotoxicity using Balb/e mice.
Seo-Hyun Moon   +25 more
core   +1 more source

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