Results 41 to 50 of about 749,929 (312)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2018 The aim of this study was to test the hypothesis that reduced pre-exercise carbohydrate (CHO) availability potentiates fat oxidation after an exhaustive high-intensity exercise bout. Eight physically active men underwent a high-intensity exercise (∼95% V̇
G.A. Ferreira +6 more
doaj +1 more source
Sử dụng thức ăn viên nuôi cá thát lát còm (Chitala chitala) thương phẩm
Tạp chí Khoa học Đại học Cần Thơ, 2022 Thí nghiệm nuôi cá thát lát còm (Chitala chitala) bằng thức ăn viên nổi được thực hiện trong các giai lưới có diện tích 20 m2/giai với 2 nghiệm thức ăn là thức ăn viên với 4 mức protein (42,5%, 38,6%, 33,6% và 33,2%) và 9% lipid cho 4 giai đoạn nuôi ...
Trần Thị Thanh Hiền +2 more
doaj +1 more source
CHO-K1, COS7, and HEK293 cells express PAR1 and PAR2 receptors.
, 2020 A. CHO-K1, COS7, and HEK293 cells naturally express high levels of PAR1 and PAR2 mRNA but express little or no PAR3 and PAR4 mRNA. qPCR analysis was used to quantify the mRNA expression.
Chester Kuei (1660933) +10 more
core +1 more source
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Khảo sát kháng thể kháng virus dại trên chó ở một số lò mổ tại thành phố Cần Thơ
Tạp chí Khoa học Đại học Cần Thơ, 2017 Khảo sát kháng thể kháng virus dại trên chó ở một số lò mổ tại thành phố Cần Thơ được tiến hành từ tháng 02/2015 đến tháng 11/2015, bằng phương pháp ELISA với bộ Kit SERELISA® Rabies Ab Mono Indirect.
Trần Ngọc Bích +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype
Journal of Pharmacological Sciences, 2004 Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi +5 more
doaj +1 more source
Biological Role of Pazopanib and Sunitinib Aldehyde Derivatives in Drug-Induced Liver Injury
Metabolites, 2022 Tyrosine kinase inhibitors pazopanib and sunitinib are both used to treat advanced renal cell carcinoma but expose patients to an increased risk of hepatotoxicity.
Maud Maillard +9 more
doaj +1 more source