Results 101 to 110 of about 228,451 (311)

The effect of hyperthermia on the phosphoinositide signalling system of tumour cells [PDF]

open access: yes, 1994
The effect of heat on the phosphoinositide signalling pathway was investigated in CHO-K1 cells and WRK-1 cells. Heat caused a decrease in 1,2-diacylglycerol (1,2- DAG) levels but did not have any effect on monoacylglycerol (MAG) levels in both cell types.
Kwong, Wing Yee
core  

CHO- and CHO-CEACAM1 derived MVs induce the CEACAM1-L tyrosine phosphorylation in confluent HT29 cells. [PDF]

open access: yes, 2013
CEACAM1 immunoprecipitates of confluent HT29 cells treated for 15 min with CHO- and CHO-CEACAM1 derived MVs were probed for tyrosine phosphorylation (upper panel) and CEACAM1 (lower panel) as control for equal loading.
Janine D. Dreesen (457081)   +6 more
core   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

open access: yesAdvanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho   +8 more
wiley   +1 more source

Electrolyte‐Induced Cu+ Preservation Results in a Selectivity Switch of Electrocatalytic CO2 Reduction at a Copper‐Organic Framework as Electrocatalyst

open access: yesAdvanced Functional Materials, EarlyView.
The active role of KCl as a neutral electrolyte enables switching the selectivity on a Cu organic framework from C1 to C2+ products during electrocatalytic CO2 reduction. ABSTRACT We introduce a copper‐nicotinate (Cu‐NA) framework as a halogenide‐stabilized Cu+/Cu0 pre‐catalyst for electrocatalytic CO2 reduction with high C2+ selectivity in a “neutral”
Anirudha Shekhawat   +11 more
wiley   +1 more source

Codon Optimization of Stem Cell Factor (SCF) gene and evaluation of this gene expression using vector pBudCE4.1 in Chinese Hamster Ovary cells (CHO) [PDF]

open access: yesJournal of Fasa University of Medical Sciences, 2017
Background & Objective: Stem cell factor (SCF) is a blood cytokine which can play a significant role in the differentiation of blood precursor cells, survival, proliferation and differentiation of mast cells, and it can also increase the proliferation ...
ehsan heidari   +3 more
doaj   +1 more source

Impact of N-Acetylation on DNA Damage and Oxidative Stress Responses in Mammalian Cells and Human Hepatocytes Treated with Hydralazine

open access: yesBiomolecules
Hydralazine is widely used to treat hypertension during pregnancy and has epigenetic effects in cancer therapy. Cryoplatable human hepatocytes showed concentration-dependent increase in DNA damage response (linear trend p = 0.0069) following 24 h ...
Mariam R. Habil   +7 more
doaj   +1 more source

Development of a stable eukaryotic strain producing fully human monoclonal antibody on the basis of the human antibody against ectromelia virus

open access: yesВавиловский журнал генетики и селекции, 2018
Fully­human antibodies have a great therapeutic importance; however, the development of stable strains providing a high level of production of full­size antibodies is a challenging task, as antibody molecules contain two types of polypeptide chains.
A. L. Matveev   +6 more
doaj   +1 more source

scFv production in transfected CHO cells. [PDF]

open access: yes, 2013
CHO cells were transfected with pMAC/PS (empty vector) or pMAC/PS-scFv and after 48 hours, the supernatants were collected, and the secretion of scFv was measured by dot immunoblotting. Supernatants from non-transfected CHO cell were used as the control (
José D. Lopes (357954)   +6 more
core   +1 more source

Glucose Deprivation‐Driven Concurrent Induction of Apoptosis/Disulfidptosis/Ferroptosis by Tumor Targeting Nanoassemblies in Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Innovative hybrid nanoassemblies installed with ferrocene, D‐α‐tocopherol succinate, and phloretin exploit the metabolic vulnerability of triple‐negative breast cancer under glucose starvation. By blocking glucose uptake, this single nanoplatform simultaneously orchestrates apoptosis, disulfidptosis, and ferroptosis to achieve synergistic and ...
Song Yi Lee   +10 more
wiley   +1 more source

Coordinate expression of the α and β subunits of heterotrimeric G proteins involves regulation of protein degradation in CHO cells [PDF]

open access: yes, 2003
Individual cell types express a characteristic balance between heterotrimeric G protein α and βγ subunits, but little is known about the regulatory mechanism. We systemically examined the regulatory mechanism in CHO cells. We found that expression of Gαs,
Juhnn, Yong-Sung   +13 more
core   +1 more source

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