Results 231 to 240 of about 663,360 (333)

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Production of multi-subunit proteins in CHO cells by transposase-mediated integration of subunit-splitting vectors. [PDF]

Sci Rep
Yamaguchi K, Ogawa R, Tsukahara M, Kawakami K.   +3 more
europepmc   +1 more source

The efficacy of alginate encapsulated CHO-K1 single chain-TRAIL producer cells in the treatment of brain tumors

, 2006
Jos M.A. Kuijlen, Bart J. de Haan, Wijnand Helfrich, J. de Boer, Douwe F. Samplonius, Jan Jakob A. Mooij, Paul de Vos   +6 more
openalex   +2 more sources

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

Endogenous Retrovirus-Like Particle-Deficient CHO Cells Can be Generated by CRISPR or shRNA and Enriched Based on Cell-Surface Expression of Retroviral Envelope Protein. [PDF]

Biotechnol Bioeng
Stuible M, Alpuche-Lazcano SP, Gervais C, Ouimet M, Lippens J, Pagé M, Morasse A, Moraitis AN, Durocher Y.   +8 more
europepmc   +1 more source

Large Anomalous Hall Effect, Non‐Vanishing Berry Curvature in (110) FeRh Antiferromagnet Films via Interface Strain

Advanced Science, EarlyView.
This study demonstrates a strain‐tunable anomalous Hall response in the (110)‐oriented FeRh thin film. First‐principles calculations reveal that strain‐induced symmetry lowering redistributes Berry curvature near the Fermi level via band shifts and avoided crossings.
Yun‐Ho Kim, Gil‐Sung Kim, Jae Won Choi, Jung‐Min Cho, Won‐Yong Lee, Hongkee Yoon, Yeonho Choi, Shelby Fields, Steven Bennett, Mona Zebarjadi, Young‐Gui Yoon, Sang‐Kwon Lee   +11 more
wiley   +1 more source

Optimization of a novel expression system for recombinant protein production in CHO cells. [PDF]

Sci Rep
Zhang J, Du C, Pan Y, Zhang Z, Feng R, Ma M, Wang T.   +6 more
europepmc   +1 more source

δ‐Opioid receptors stimulate GLUT1‐mediated glucose uptake through Src‐ and IGF‐1 receptor‐dependent activation of PI3‐kinase signalling in CHO cells

, 2011
Maria C. Olianas, Simona Dedoni, Pier Luigi Onali   +2 more
openalex   +2 more sources

Defect‐Engineered MOF/COF S‐Scheme Heterojunction With Dual‐Channel Charge Transport for Ultraefficient Solar‐Powered Heavy Metal Remediation

Advanced Science, EarlyView.
Covalent bond MOF/COF S‐scheme which generated via vacuum‐induced oxygen vacancies are report. OVs at the interface can trigger a dual‐channel charge transport mechanism, significantly enhancing catalytic performance. This work not only designs a high‐performance photocatalysts for environmental remediation, but also induces a new concept of “defect ...
Yuqian Zhong, Xinpeng Wang, Weiqun Shi, Liyong Yuan   +3 more
wiley   +1 more source

Dynamic metabolic flux analysis using B-splines to study the effects of temperature shift on CHO cell metabolism

, 2015
Verónica S. Martínez, Maria Buchsteiner, Peter P. Gray, Lars K. Nielsen, Lake‐Ee Quek   +4 more
openalex   +1 more source