Results 61 to 70 of about 228,451 (311)

Mini-Column for Cytoadherence: A New Method for Measuring the Relative Size of Binding Subpopulations in Plasmodium falciparum Isolates [PDF]

open access: yesIranian Journal of Parasitology, 2011
Background: Cytoadherence of Plasmodium falciparum- infected red blood cells to endothelial cells is an important mechanism for parasite survival and a major trigger for diseases pathology.
N Kalantari, S Ghaffari
doaj   +1 more source

Production and purification of TGFb-1 in CHO-Cells [PDF]

open access: yesBMC Proceedings, 2011
The development of chemically well defined media is a demanding task in order to create the optimal conditions for an in vitro stem cell (SC) proliferation and differentiation system. Signals that govern SC differentiation into multiple mature cell types are provided by growth factors.
Abdulkerim Estabraq   +4 more
openaire   +3 more sources

Adaptation to suspension growth: analysing the surface of suspension growth adapted Chinese hamster ovary cells [PDF]

open access: yes, 2013
Many bio-pharmaceutical production processes are based upon the use of mammalian cell lines, such as Chinese hamster ovary (CHO) cells, capable of proliferation as single cells in suspension in a synthetic environment.
Walther, Christa G
core  

NPC1 knockout inhibited insulin signalling in CHO cells. [PDF]

open access: yes, 2014
(a) Total cell lysates of K1 CHO cells and 2–2 CHO cells were immunoblotted with anti-NPC1 antibody to determine expression levels of endogenous NPC1 and overexpressed NPC1-YFP. (b) Total cells lysates of K1 CHO cells and 2–2 CHO cells were immunoblotted
Kristen C. Thomas (521964)   +7 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells

open access: yesVirology Journal, 2006
Background Herpes simplex virus (HSV) can utilize multiple pathways to enter host cells. The factors that determine which route is taken are not clear. Chinese hamster ovary (CHO) cells that express glycoprotein D (gD)-binding receptors are model cells ...
Nicola Anthony V   +3 more
doaj   +1 more source

Chromosomal instability drives convergent and divergent evolution toward advantageous inherited traits in mammalian CHO bioproduction lineages

open access: yesiScience, 2022
Summary: Genetic instability of Chinese hamster ovary (CHO) cells is implicated in production inconsistency through poorly defined mechanisms. Using a multi-omics approach, we analyzed the variations of CHO lineages derived from CHO-K1 cells. We identify
Steve Huhn   +8 more
doaj   +1 more source

微囊化转基因细胞CHO移植抑制血管生长的抗肿瘤治疗 [PDF]

open access: yes, 2007
Microencapsulation of recombinant cells is a novel alternative approach to gene therapy of tumors. It is necessary to prepare plenty of microcapsules with better cell viability and higher endostatin production in order to bring this technology into ...
王为, 马小军, Xiaojun Ma, 张英
core  

Modulation of Phosducin-Like Protein 3 (PhLP3) Levels Promotes Cytoskeletal Remodelling in a MAPK and RhoA-Dependent Manner [PDF]

open access: yes, 2011
Background Phosducin-like protein 3 (PhLP3) forms a ternary complex with the ATP-dependent molecular chaperone CCT and its folding client tubulin. In vitro studies suggest PhLP3 plays an inhibitory role in ?-tubulin folding while conversely in vivo ...
C Mark Smales   +14 more
core   +1 more source

Reconfigurable Logic‐in‐Memory Operations Enabled by Triple‐Gated Feedback Field‐Effect Transistors for Area‐Efficient Computing

open access: yesAdvanced Engineering Materials, EarlyView.
A reconfigurable logic‐in‐memory cell composed of triple‐gated feedback field‐effect transistors implements multiple combinational logic functions within a single configuration. By utilizing program gates as dynamic input terminals, the proposed cell performs full adder, full subtractor, 2‐to‐1 multiplexer, and 4‐to‐2 encoder operations without ...
Minhyeok Seol   +5 more
wiley   +1 more source

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