Results 71 to 80 of about 228,451 (311)

Bioactivation, Mutagenicity, DNA Damage, and Oxidative Stress Induced by 3,4-Dimethylaniline

open access: yesBiomolecules
3,4-Dimethylaniline (3,4-DMA) is present in cigarette smoke and widely used as an intermediate in dyes, drugs, and pesticides. Nucleotide excision repair-deficient Chinese hamster ovary (CHO) cells stably transfected with human CYP1A2 and N ...
Mariam R. Habil   +3 more
doaj   +1 more source

Factors Affecting the Expression of Recombinant Protein and Improvement Strategies in Chinese Hamster Ovary Cells

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Recombinant therapeutic proteins (RTPs) are important parts of biopharmaceuticals. Chinese hamster ovary cells (CHO) have become the main cell hosts for the production of most RTPs approved for marketing because of their high-density suspension growth ...
Zheng-Mei Li   +7 more
doaj   +1 more source

The Anti-Inflammatory Actions of Lcy-2-Cho, a Carbazole Analogue, in Vascular Smooth Muscle Cells [PDF]

open access: yes, 2008
LCY-2-CHO has anti-infl amm atory actions on macrophages. To understand its therapeutic implication in atherosclerosis, we examined its effects on the expressions of antiinflammatory and inflammatory proteins in cultured rat aortic vascular smooth muscle
何豐名;康皓程;李旭東;趙毅;黃麗嬌;林琬琬   +1 more
core  

CYP1B1 expression in CHO cells influences psoralen-UVA sensitivity. [PDF]

open access: yes, 2013
(A) Western blot analysis of CYP1B1 and CPR expression in modified CHO cell lines was performed as described in Materials and Methods (lane 1, CHO-1B1/CPR cells; lane 2, CHO-CPR cells; lane 3, CHO cells; lane 4, control E. coli membranes).
C. Roland Wolf (293805)   +4 more
core   +1 more source

Composites of Shellac and Silver Nanowires as Flexible, Biobased, and Corrosion‐Resistant Transparent Conductive Electrodes

open access: yesAdvanced Functional Materials, EarlyView.
Shellac, a centuries‐old natural resin, is reimagined as a green material for flexible electronics. When combined with silver nanowires, shellac films deliver transparency, conductivity, and stability against humidity. These results position shellac as a sustainable alternative to synthetic polymers for transparent conductors in next‐generation ...
Rahaf Nafez Hussein   +4 more
wiley   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

Enhancing the understanding of CHO cell culture metabolic traits through integrated first-principle modelling and data-based parameter estimation [PDF]

open access: yes, 2023
openThe focus of the thesis is to develop hybrid techniques that enhance the parameter estimation procedure used to predict the behavior of CHO cellular lines.
TAMIAZZO, EDOARDO
core  

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

PD-1 blockade augments anti-neuroblastoma immune response induced by anti-GD2 antibody ch14.18/CHO

open access: yesOncoImmunology, 2017
Immunotherapy with anti-GD2 antibody (Ab) ch14.18/CHO is effective for treatment of high-risk neuroblastoma (NB) patients and is mainly based on GD2-specific Ab-dependent cellular cytotoxicity (ADCC).
Nikolai Siebert   +4 more
doaj   +1 more source

Novel role of ER stress and autophagy in Microcystin-LR induced apoptosis in Chinese hamster ovary cells

open access: yesFrontiers in Physiology, 2016
Microcystin-LR (MC-LR) is a ubiquitous peptide that exhibits strong reproductive toxicity, although the mechanistic basis for such toxicity remains largely unknown.
Shenshen Zhang   +7 more
doaj   +1 more source

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