Results 141 to 150 of about 631,023 (263)

The cone method: Inferring decision times from single-trial 3D movement trajectories in choice behavior. [PDF]

Behav Res Methods, 2021
Ulbrich P, Gail A.
europepmc   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Role of posterior medial thalamus in the modulation of striatal circuitry and choice behavior. [PDF]

Elife
Yonk AJ, Linares-García I, Pasternak L, Juliani SE, Gradwell MA, George AJ, Margolis DJ.   +6 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Using recurrent neural network to estimate irreducible stochasticity in human choice behavior. [PDF]

Elife
Ger Y, Shahar M, Shahar N.
europepmc   +1 more source

Remote, brain region-specific control of choice behavior with ultrasonic waves. [PDF]

Sci Adv, 2020
Kubanek J, Brown J, Ye P, Pauly KB, Moore T, Newsome W.   +5 more
europepmc   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Infection, Choice Behavior, and Cross-Infectivity of the Sculpted Damsel Bug, <i>Nabis roseipennis</i>, Offered the Tarnished Plant Bug, <i>Lygus lineolaris</i>, Infected with Entomopathogenic Nematodes. [PDF]

Insects
Glover JP, Spaulding N, Nufer MI, George J, Portilla M, Reddy GVP.   +5 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source