Results 151 to 160 of about 3,329,118 (351)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Descrição de algumas variáveis no comportamento de esperar por recompensas previamente escolhidas

open access: yesPsicologia USP
O presente experimento foi realizado com o objetivo de verificar se a escolha por recompensas dependia do conhecimento da situação, de treino anterior em autocontrole, ou se a situação experimental favorecia a aprendizagem de autocontrole, definido como ...
Rachel Rodrigues Kerbauy   +1 more
doaj  

Entropy-based metrics for predicting choice behavior based on local response to reward. [PDF]

open access: yesNat Commun, 2021
Trepka E   +5 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Rapid modulation of choice behavior by ultrasound on the human frontal eye fields. [PDF]

open access: yesNat Commun
Farboud S   +8 more
europepmc   +2 more sources

Food choices determinants in à la carte restaurants

open access: yesO Mundo da Saúde, 2014
It is remarkable the increase in the number of restaurants, especially à la carte ones, and the analysis of the determinants of food choices in these environments may suggest changes in the food pattern. In this sense, the aim of the present study was to
Rita de Cássia Ribeiro   +3 more
doaj  

The Logit Equilibrium: A Perspective on Intuitive Behavioral Anomalies [PDF]

open access: yes
This paper considers a class of models in which rank-based payoffs are sensitive to small amounts of noise in decision making. Examples include auction, price-competition, coordination, and location games.
Charles A. Holt   +2 more
core  

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