Results 101 to 110 of about 89,075 (280)

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

EASL-ILCA Clinical Practice Guidelines on Intrahepatic Cholangiocarcinoma.

Journal of Hepatology, 2023
D. Alvaro, G. Gores, J. Walicki, C. Hassan, Gonzalo Sapisochin, M. Komuta, A. Forner, J. Valle, A. Laghi, S. Rizvi, Joong-Won Park, R. Kelley, M. Reig, B. Sangro   +13 more
semanticscholar   +1 more source

Prolonged oxidative stress down-regulates Early B cell factor 1 with inhibition of its tumor suppressive function against cholangiocarcinoma genesis

Redox Biology, 2018
Early B cell factor 1 (EBF1) is a transcription factor involved in the differentiation of several stem cell lineages and it is a negative regulator of estrogen receptors. EBF1 is down-regulated in many tumors, and is believed to play suppressive roles in
Napat Armartmuntree, Mariko Murata, Anchalee Techasen, Puangrat Yongvanit, Watcharin Loilome, Nisana Namwat, Chawalit Pairojkul, Chadamas Sakonsinsiri, Somchai Pinlaor, Raynoo Thanan   +9 more
doaj   +1 more source

Intrahepatic Cholangiocarcinoma: Continuing Challenges and Translational Advances

Hepatology, 2019
Intrahepatic cholangiocarcinoma (iCCA) has over the last 10‐20 years become the focus of increasing concern, largely due to its rising incidence and high mortality rates worldwide.
A. Sirica, G. Gores, J. Groopman, F. Selaru, M. Strazzabosco, X. Wei Wang, A. Zhu   +6 more
semanticscholar   +1 more source

Incorporation of Microsatellite Instability and Tumor-Infiltrating Lymphocytes in Opisthorchis viverrini-Associated Cholangiocarcinoma: Predicting Patient Outcomes

Journal of Molecular Pathology
Background: Cholangiocarcinoma (CCA) has the highest incidence in Northeastern Thailand, where patients generally present with late diagnosis and poor prognosis.
Natcha Khuntikeo, Apiwat Jareanrat, Vasin Thanasukarn, Tharatip Srisuk, Vor Luvira, Watcharin Loilome, Poramate Klanrit, Anchalee Techasen, Jarin Chindaprasirt, Prakasit Sa-Ngiamwibool, Chaiwat Aphivatanasiri, Sureerat Padthaisong, Piya Prajumwongs, Attapol Titapun   +13 more
doaj   +1 more source

Network pharmacology- and cell-based assessments identify the FAK/Src pathway as a molecular target for the antimetastatic effect of momordin Ic against cholangiocarcinoma

Heliyon
Previous studies have indicated the efficacy of momordin Ic (MIc), a plant-derived triterpenoid, against several types of cancers, implying its potential for further development.
Piman Pocasap, Auemduan Prawan, Sarinya Kongpetch, Laddawan Senggunprai   +3 more
doaj   +1 more source

Establishment of Highly Transplantable Cholangiocarcinoma Cell Lines from a Patient-Derived Xenograft Mouse Model

Cells, 2019
Cholangiocarcinoma (CCA) is a deadly malignant tumor of the liver. It is a significant health problem in Thailand. The critical obstacles of CCA diagnosis and treatment are the high heterogeneity of disease and considerable resistance to treatment ...
Kulthida Vaeteewoottacharn, Chawalit Pairojkul, Ryusho Kariya, Kanha Muisuk, Kanokwan Imtawil, Yaovalux Chamgramol, Vajarabhongsa Bhudhisawasdi, Narong Khuntikeo, Ake Pugkhem, O-Tur Saeseow, Atit Silsirivanit, Chaisiri Wongkham, Sopit Wongkham, Seiji Okada   +13 more
doaj   +1 more source

A Multi-Institutional International Analysis of Textbook Outcomes Among Patients Undergoing Curative-Intent Resection of Intrahepatic Cholangiocarcinoma.

JAMA Surgery, 2019
Importance Composite measures may be superior to individual measures for the analysis of hospital performance and quality of surgical care. Objective To determine the incidence of a so-called textbook outcome, a composite measure of the quality of ...
Katiuscha Merath, Qinyu Chen, F. Bagante, F. Bagante, S. Alexandrescu, H. Marques, L. Aldrighetti, S. Maithel, C. Pulitanò, M. Weiss, T. Bauer, F. Shen, G. Poultsides, O. Soubrane, G. Martel, B. Koerkamp, A. Guglielmi, E. Itaru, J. Cloyd, T. Pawlik   +19 more
semanticscholar   +1 more source

Transcriptome changes of liver fluke Opisthorchis viverrini in diabetic hamsters

Parasite
A recent study in hamsters showed that infection with the liver fluke Opisthorchis viverrini in diabetic hosts worsens the severity of hepatobiliary disease.
Chaidee Apisit, Charoenram Naruechar, Sengthong Chatchawan, Dangtakot Rungtiwa, Pinlaor Porntip, Pongking Thatsanapong, Pinlaor Somchai   +6 more
doaj   +1 more source