Results 211 to 220 of about 89,075 (280)

Unveiling a BRAF Signature Proficient in Accurately Capturing Oncogenic Activity and Guiding Prognostic Prediction Across Multiple Cancers

MedComm, Volume 7, Issue 2, February 2026.
The BRAF25 meta‐signature effectively captures BRAF‐driven oncogenic activity. By enabling precise patient stratification with distinct mutation profiles, BRAF25 identifies BRAF‐active tumor subtypes and provides superior prognostic value compared with mutation status alone.
Kaidi Yang, Shihui Fu, Jingbing Liang, Lijuan Ding, Junhao You, Fang Li, Ye Yuan, Xiu‐Wu Bian   +7 more
wiley   +1 more source

Posterior Reversible Encephalopathy Syndrome in a Patient With Intrahepatic Cholangiocarcinoma: Converging Effects of Acute Hypertension and Cisplatin Therapy. [PDF]

Cureus
Annan GK, Awah J, Terrero DA, Odeyinka O, Makaya BM.   +4 more
europepmc   +1 more source

Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies

MedComm, Volume 7, Issue 2, February 2026.
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu, Zhi‐Shan Ge, Qing‐Yue Cao, Zi‐Han Li, An Zhang, Hai‐Dong Zhu, Gao‐Jun Teng   +6 more
wiley   +1 more source

Preoperative Prognostic Score for Patients with Intrahepatic Cholangiocarcinoma Undergoing Curative-Intent Resection. [PDF]

Med Sci (Basel)
Chindaprasirt J, Sanlung T, Watcharenwong P, Thanasukarn V, Jareanrat A, Khuntikeo N, Srisuk T, Sa-Ngiamwibool P, Aphivatanasiri C, Loilome W, Prajumwongs P, Titapun A.   +11 more
europepmc   +1 more source

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

MedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao, Xiaojie Qu, Yiqi Wang, Dan Huang, Huiling Zhang, Mingyuan Dong, Han Sun, Zhaogang Yang, Xuefeng Li   +8 more
wiley   +1 more source

Lymphocyte to C-reactive protein ratio as a novel inflammatory biomarker: Validation and clinical relevance as an independent prognostic factor in cholangiocarcinoma. [PDF]

World J Gastrointest Oncol
Xiao F, Zhou DH, Liu GW, Lin CW, Wu ZY, Yu H, Gong W, Tan WF.   +7 more
europepmc   +1 more source

Organ‐on‐a‐Chip Technology and Global Multi‐Omics: Current Applications and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Comparative analysis of multiple cell culture models. The 3D microfluidic organ‐on‐a‐chip, which is superior to the existing models in multiple aspects, can be more conducive to new studies and discoveries related to human beings. Created with BioRender (www.biorender.com).
Xuxia Cao, Congmin Xia, Caifeng Li, Shiwen Deng, Junxian Cao, Hongjun Yang, Shaoping Wang, Peng Chen   +7 more
wiley   +1 more source

Molecular Testing for Intrahepatic Cholangiocarcinoma: What, When, How? [PDF]

J Gastrointest Cancer
Barsch M, Dopfer EP, Schultheis AM, Quante M.   +3 more
europepmc   +1 more source

Calycosin Targets the CYP1B1‐AKT/SP1‐GPX4 Axis to Modulate Ferroptosis in Colorectal Carcinogenesis

Phytotherapy Research, Volume 40, Issue 2, Page 721-736, February 2026.
Mechanism of Calycosin in Regulating Ferroptosis in Colorectal Cancer via Binding to CYP1B1. ABSTRACT Calycosin, a natural flavonoid small‐molecule compound derived from traditional Chinese medicine, has demonstrated remarkable pharmacological activity in the field of cancer therapy.
Lihan Bie, Xin Lei, Di Wu, Yang Zhang, Chengshan He, Luyao Liu, Jiawei Zhou, Xin Zhou, Yingying Lu, Zheng Xu   +9 more
wiley   +1 more source