Results 221 to 230 of about 89,075 (280)

Secretory leukocyte protease inhibitor (SLPI) promotes cholangiocarcinoma progression via inflammation-associated and vasculogenic mechanisms. [PDF]

PLoS One
Chueajedton K, Chueaiphuk C, Inpad J, Kumphune S, Kaewkong W, Surangkul D, Sawanyawisuth K, Cha'on U, Phimsen S.   +8 more
europepmc   +1 more source

Overexpression of Transferrin Receptor in Esophageal Squamous Cell Cancer Suggests Poor Prognosis and Potential Therapy

Cancer Science, Volume 117, Issue 2, Page 393-406, February 2026.
This study aimed to evaluate transferrin receptor (TfR) expression in human esophageal squamous cell cancer (ESCC) specimens and investigate the correlation between TfR overexpression and clinicopathological characteristics. Furthermore, we explored the potential of targeting iron metabolism pathways as a novel therapeutic strategy for ESCC.
Naoki Ikenaga, Tsuyoshi Takahashi, Koji Tanaka, Satoshi Serada, Minoru Fujimoto, Kota Momose, Kotaro Yamashita, Tomoki Makino, Takuro Saito, Kazuyoshi Yamamoto, Yukinori Kurokawa, Kiyokazu Nakajima, Tomomi Fujii, Eiichi Morii, Tetsuji Naka, Hidetoshi Eguchi, Yuichiro Doki   +16 more
wiley   +1 more source

MBNL3 regulates tumor progression and metastasis in cholangiocarcinoma and serves as a prognostic biomarker. [PDF]

Sci Rep
Zhou H, Wang Y, Zhao K, Li M, Ni X, Chen S, Yan T, Xu J.   +7 more
europepmc   +1 more source

Spatial Location of SPP1+TAMs and Mutually Exclusive Subsets Based on Single‐Cell and Transcriptome Data

Cancer Science, Volume 117, Issue 2, Page 548-565, February 2026.
This study indicates that SPP1, as an important regulator of tumor progression, is upregulated in various tumors and has been associated with a poor prognosis. SPP1+M2 has a unique spatial location at the forefront of tumor invasion and metastasis, thereby promoting tumor progression. MARCO+M2, which forms a mutually exclusive relationship with SPP1+M2,
Xuan Luo, JianGuo Xu, ZhiYuan Wang, XiaoFang Wang, YangHao Wang, Yu Zhang, FangFang Li, Hui Fang, XiaoYun Huang, MuYe Li, XiaoJuan Liu, JiHong Tang, PeiYang Fan, GuoJing Zhao, YongWen He, Li Bian   +15 more
wiley   +1 more source

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk-ChA-1 and Mz-ChA-1 cell growth by inducing caspase-dependent apoptosis and downregulation of survivin and Bcl-2 expression. [PDF]

Oncol Lett
Zhong F, Yang J, Tong ZT, Chen LL, Fan LL, Wang F, Zha XL, Li J.   +7 more
europepmc   +1 more source

A YAP/TAZ–CDC6 Axis Initiates and Maintains Malignant Transformation

Cancer Science, Volume 117, Issue 2, Page 353-363, February 2026.
This study demonstrates that constitutive activation of YAP or TAZ is sufficient to induce and maintain malignant transformation in fibroblasts, identifying them as essential oncogenic drivers. Transcriptomic and functional analyses revealed CDC6 as a critical downstream effector of YAP/TAZ, with elevated expression linked to tumorigenesis across ...
David Nduru, Yudai Ohta, Akihiro Nita, Mayumi Niimura, Samson Ngurari, Toshiro Moroishi   +5 more
wiley   +1 more source

Continuous Renal Replacement Therapy During Liver Transplant: The Anesthesiologist‐Nephrologist Collaboration at a Tertiary University Hospital in Italy

Clinical Transplantation, Volume 40, Issue 2, February 2026.
ABSTRACT Background: Acute kidney injury frequently complicates the end stages of liver diseases, worsening the condition of patients waiting for liver transplants. Continuous renal replacement therapy during liver transplant is still a limited experience, with large variability in the indication criteria.
Cristiana Laici, Davide Ricci, Dino Gibertoni, Elena Mancini, Annalisa Zucchelli, Antonio Siniscalchi   +5 more
wiley   +1 more source

Exploring the role of disulfidptosis‑related signatures in immune microenvironment, prognosis and therapeutic strategies of cholangiocarcinoma. [PDF]

Oncol Rep
Chen Y, Wu J, Zhu D, Jiang L, Wang J, Zhang D, He W.   +6 more
europepmc   +1 more source

Issue Information

Liver International Communications, Volume 7, Issue 1, March 2026.
wiley   +1 more source