Results 51 to 60 of about 89,075 (280)

Intrahepatic Cholangiocarcinoma

Seminars in Interventional Radiology, 2020
AbstractCholangiocarcinoma is the second most common primary malignancy of the liver. This review will focus on the mass-forming intrahepatic type of this disease and discuss the role of medical, surgical, and radiation oncology in managing this difficult disease.
Pouya, Entezari, Ahsun, Riaz
openaire   +3 more sources

Intrahepatic sarcomatoid cholangiocarcinoma: a rare cholangiocarcinoma subtype

Revista Española de Enfermedades Digestivas, 2022
We report a case of Intrahepatic sarcomatoid cholangiocarcinoma(ISCC) , which is a rare subtype of cholangiocarcinoma. Primary sarcomatoid hepatocellular carcinoma degeneration is common after anticancer chemotherapy or hepatic artery embolization.however, intrahepatic sarcomatoid cholangiocarcinoma degeneration is relatively rare.Patients typically ...
Li, Shen, Jun, Xu, Aoqing, Wang, Jin, Zheng   +3 more
openaire   +2 more sources

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

FOXM1c is the predominant FOXM1 isoform expressed in cholangiocarcinoma that associated with metastatic potential and poor prognosis of patients

Heliyon, 2021
Forkhead box M1 (FOXM1) is a transcriptional factor which plays an important role in oncogenesis. Four FOXM1 isoforms, FOXM1a, FOXM1b, FOXM1c and FOXM1d, are known so far. Different FOXM1 isoforms influence progression of cancer in different cancer types.
Nathakan Klinhom-on, Wunchana Seubwai, Kanlayanee Sawanyawisuth, Worachart Lert-itthiporn, Sakda Waraasawapati, Marutpong Detarya, Sopit Wongkham   +6 more
doaj   +1 more source

Gut microbiome directs hepatocytes to recruit MDSC and promote cholangiocarcinoma.

Cancer Discovery, 2020
Gut dysbiosis is commonly observed in patients with cirrhosis and chronic gastrointestinal disorders, however, its effect on anti-tumor immunity in the liver is largely unknown.
Qian-fei Zhang, Chi Ma, Yi Duan, B. Heinrich, U. Rosato, L. Diggs, Lichun Ma, S. Roy, Qiong Fu, Zachary J. Brown, S. Wabitsch, Vishal Thovarai, Jianyang Fu, D. Feng, B. Ruf, L. Cui, Varun Subramanyam, K. Frank, Sophie Wang, D. Kleiner, T. Ritz, C. Rupp, B. Gao, T. Longerich, A. Kroemer, X. Wang, M. Ruchirawat, F. Korangy, B. Schnabl, G. Trinchieri, T. Greten   +30 more
semanticscholar   +1 more source

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

Advanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche, Raisatun Nisa Sugiyanto, Kira Gür, Alina Krumme, Maxime Le Marois, Angelika Fraas, Aslihan Inal, Mario Huerta, Vanessa Henriques, Eva Eiteneuer, Thomas Albrecht, Alphonse Charbel, Michael T. Dill, Carsten Sticht, Carolina De La Torre, Stefan Pusch, Arianeb Mehrabi, Kai Breuhahn, Junfang Ji, Peter Schirmacher, Benjamin Goeppert, Stephanie Roessler   +21 more
wiley   +1 more source

Serum peptide biomarkers by MALDI-TOF MS coupled with machine learning for diagnosis and classification of hepato-pancreato-biliary cancers

Scientific Reports
This study aimed to investigate the potential of peptide mass fingerprints (PMFs) of the serum peptidome using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), in combination with machine learning algorithms ...
Piya Prajumwongs, Attapol Titapun, Vasin Thanasukarn, Apiwat Jareanrat, Natcha Khuntikeo, Krit Rattanarak, Nisana Namwat, Poramate Klanrit, Arporn Wangwiwatsin, Jarin Chindaprasirt, Supinda Koonmee, Prakasit Sa-Ngiamwibool, Nattha Muangritdech, Sawanya Charoenlappanit, Janthima Jaresitthikunchai, Sittiruk Roytrakul, Watcharin Loilome   +16 more
doaj   +1 more source

Upregulation of transferrin receptor-1 induces cholangiocarcinoma progression via induction of labile iron pool

Tumor Biology, 2017
Labile iron pool is a cellular source of ions available for Fenton reactions resulting in oxidative stress. Living organisms avoid an excess of free irons by a tight control of iron homeostasis.
Wassana Jamnongkan, Raynoo Thanan, Anchalee Techasen, Nisana Namwat, Watcharin Loilome, Piyapharom Intarawichian, Attapol Titapun, Puangrat Yongvanit   +7 more
doaj   +1 more source

Clinical pharmacokinetics of quinine and its relationship with treatment outcomes in children, pregnant women, and elderly patients, with uncomplicated and complicated malaria: a systematic review

Malaria Journal, 2022
Background Standard dosage regimens of quinine formulated for adult patients with uncomplicated and complicated malaria have been applied for clinical uses in children, pregnant women, and elderly.
Teerachat Saeheng, Kesara Na-Bangchang
doaj   +1 more source

ESMO Scale for Clinical Actionability of Molecular Targets driving targeted treatment in patients with cholangiocarcinoma.

Clinical Cancer Research, 2022
Purpose: Treatment options for advanced cholangiocarcinoma are limited and prognosis is poor. Cholangiocarcinomas are highly heterogeneous at the molecular level, with divergent patterns between intrahepatic and extrahepatic forms, intrahepatic being ...
H. Verdaguer, T. Saurí, D. Acosta, Magdalena Guardiola, Alexandre Sierra, J. Hernando, P. Nuciforo, J. Miquel, Cristina Molero, Sandra Peiró, Q. Serra-Camprubí, G. Villacampa, S. Aguilar, A. Vivancos, J. Tabernero, R. Dienstmann, T. Macarulla   +16 more
semanticscholar   +1 more source