Results 61 to 70 of about 106,739 (248)

Upregulation of transferrin receptor-1 induces cholangiocarcinoma progression via induction of labile iron pool

open access: yesTumor Biology, 2017
Labile iron pool is a cellular source of ions available for Fenton reactions resulting in oxidative stress. Living organisms avoid an excess of free irons by a tight control of iron homeostasis.
Wassana Jamnongkan   +7 more
doaj   +1 more source

Performance of Mini Parasep® SF stool concentrator kit, Kato-Katz, and formalin-ethyl acetate concentration methods for diagnosis of opisthorchiasis in Northeast Thailand

open access: yesParasites & Vectors, 2022
Background Control and elimination of the liver fluke (Opisthorchis viverrini) is a primary preventive strategy against cholangiocarcinoma in Southeast Asia.
Kulthida Y. Kopolrat   +14 more
doaj   +1 more source

Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas [PDF]

open access: yes, 2019
The bile duct system and pancreas show many similarities due to their anatomical proximity and common embryological origin. Consequently, preneoplastic and neoplastic lesions of the bile duct and pancreas share analogies in terms of molecular ...
Alvaro, D   +10 more
core   +1 more source

Identification of serum metabolite biomarkers and metabolic reprogramming mechanisms to predict recurrence in cholangiocarcinoma

open access: yesScientific Reports
Cholangiocarcinoma (CCA) has high recurrence rates that severely limit long-term survival. Effective tools for accurate recurrence monitoring and diagnosis remain lacking.
Piya Prajumwongs   +13 more
doaj   +1 more source

Clinical pharmacokinetics of quinine and its relationship with treatment outcomes in children, pregnant women, and elderly patients, with uncomplicated and complicated malaria: a systematic review

open access: yesMalaria Journal, 2022
Background Standard dosage regimens of quinine formulated for adult patients with uncomplicated and complicated malaria have been applied for clinical uses in children, pregnant women, and elderly.
Teerachat Saeheng, Kesara Na-Bangchang
doaj   +1 more source

A deep learning pipeline for localization, differentiation, and uncertainty estimation of liver lesions using multi-phasic and multi-sequence MRI [PDF]

open access: yesarXiv, 2021
Objectives: to propose a fully-automatic computer-aided diagnosis (CAD) solution for liver lesion characterization, with uncertainty estimation. Methods: we enrolled 400 patients who had either liver resection or a biopsy and was diagnosed with either hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma, or secondary metastasis, from 2006 ...
arxiv  

Ureteropelvic junction obstruction caused by metastatic cholangiocarcinoma [PDF]

open access: yes, 2019
We describe the rare case of a 61-year-old female with right ureteropelvic junction (UPJ) obstruction caused by metastatic cholangiocarcinoma. Her past medical history was notable for cholangiocarcinoma treated with neoadjuvant chemoradiation and two ...
Figenshau, Robert S   +2 more
core   +1 more source

The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma [PDF]

open access: yes, 2019
Cholangiocarcinoma (CCA) is an aggressive cancer with high resistance to chemotherapeutics. CCA is enriched in cancer stem cells, which correlate with aggressiveness and prognosis.
Adorini, L.   +19 more
core   +3 more sources

NcRNAs and Cholangiocarcinoma [PDF]

open access: yesJournal of Cancer, 2018
Cholangiocarcinoma (CCA) is the most common primary biliary malignancy with poor prognosis. Less understanding of its etiology and pathogenesis makes the diagnosis and therapy difficult. Recently, accumulating evidences have demonstrated that deregulated expression of non-coding RNAs (ncRNAs) is closely associated with the etiopathogenesis of CCA ...
Li Zhenglong   +6 more
openaire   +3 more sources

Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholagnitis [PDF]

open access: yes, 2018
The non-invasive differentiation of malignant and benign biliary disease is a clinical challenge. Carbohydrate antigen 19-9 (CA19-9), leucine-rich α2-glycoprotein (LRG1), interleukin 6 (IL6), pyruvate kinase M2 (PKM2), cytokeratin 19 fragment (CYFRA21.1)
Blyuss, O   +9 more
core   +2 more sources

Home - About - Disclaimer - Privacy