Results 21 to 30 of about 122,361 (297)

Role of the Microbiome in the Pathogenesis of COVID-19

Frontiers in Cellular and Infection Microbiology, 2022
The ongoing pandemic coronavirus disease COVID-19 is caused by the highly contagious single-stranded RNA virus, SARS-coronavirus 2 (SARS-CoV-2), which has a high rate of evolution like other RNA viruses.
Rituparna De, Rituparna De, Shanta Dutta
doaj   +1 more source

Development and evaluation of a PCR assay for rapid detection of azithromycin resistant Campylobacter isolated from diarrhoeal patients in Kolkata, India

Gut Pathogens, 2017
Background Campylobacter is a well-known bacterial pathogen for triggering acute gastroenteritis in humans both in developed and developing countries. This organism is highly resistant to fluoroquinolones.
Piyali Mukherjee, Shanta Dutta, Asish K. Mukhopadhyay   +2 more
doaj   +1 more source

Determinants of optimum exclusive breastfeeding duration in rural India: a mixed method approach using cohort and content analysis design

International Breastfeeding Journal, 2021
Background Despite established benefits, exclusive breastfeeding (EBF) rate remains poor in India. This study measured the rate of early initiation of breastfeeding and EBF up to 42 days postpartum period and the reasons associated with early ...
Falguni Debnath, Nilanjan Mondal, Alok Kumar Deb, Debjit Chakraborty, Subhrangshu Chakraborty, Shanta Dutta   +5 more
doaj   +1 more source

Deciphering the genetic network and programmed regulation of antimicrobial resistance in bacterial pathogens

Frontiers in Cellular and Infection Microbiology, 2022
Antimicrobial resistance (AMR) in bacteria is an important global health problem affecting humans, animals, and the environment. AMR is considered as one of the major components in the “global one health”.
Thandavarayan Ramamurthy, Amit Ghosh, Goutam Chowdhury, Asish K. Mukhopadhyay, Shanta Dutta, Shin-inchi Miyoshi, Shin-inchi Miyoshi   +6 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Haitian Variant Vibrio cholerae O1 Strains Manifest Higher Virulence in Animal Models

Frontiers in Microbiology, 2019
Vibrio cholerae causes fatal diarrheal disease cholera in humans due to consumption of contaminated water and food. To instigate the disease, the bacterium must evade the host intestinal innate immune system; penetrate the mucus layer of the small ...
Priyanka Ghosh, Ritam Sinha, Prosenjit Samanta, Dhira Rani Saha, Hemanta Koley, Shanta Dutta, Keinosuke Okamoto, Amit Ghosh, T. Ramamurthy, Asish K. Mukhopadhyay   +9 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Epidemiology of typhoid and paratyphoid fever in India

Journal of Infection in Developing Countries, 2008
Enteric fever (typhoid and paratyphoid fever) is a major human bacterial infection. Although the disease is not common in industrialised countries, it remains an important and persistent health problem in developing nations.
Suman Kanungo, Shanta Dutta, Dipika Sur
doaj   +1 more source

An Experimental Adult Zebrafish Model for Shigella Pathogenesis, Transmission, and Vaccine Efficacy Studies

Microbiology Spectrum, 2022
Shigellosis has been a menace to society for ages. The absence of an effective vaccine against Shigella, improper sanitation, and unhygienic use of food and water allow the disease to flourish.
Debaki R. Howlader, Ushasi Bhaumik, Prolay Halder, Aishwarya Satpathy, Sounak Sarkar, Mrinalini Ghoshal, Suhrid Maiti, Jeffrey H. Withey, Jiro Mitobe, Shanta Dutta, Hemanta Koley   +10 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source