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Cholera, the Current Status of Cholera Vaccines and Recommendations for Travellers [PDF]
Cholera is endemic in approximately 50 countries, primarily in Africa and South and Southeast Asia, and in these areas, it remains a disease associated with poverty.
Giovanni Gabutti+8 more
doaj +7 more sources
An Update on Cholera Immunity and Current and Future Cholera Vaccines [PDF]
Individual resistance to cholera infection and disease depends on both innate host factors and adaptive immunity acquired by a previous infection or vaccination.
Jan Holmgren
doaj +3 more sources
Oral cholera vaccines and their impact on the global burden of disease [PDF]
With one-third of nations at risk of cholera, we can expect to experience massive, rapidly disseminated, and prolonged cholera outbreaks such as those recently experienced in Yemen and Haiti.
Thomas F. Wierzba
doaj +3 more sources
Achievements and challenges for the use of killed oral cholera vaccines in the global stockpile era [PDF]
Cholera remains an important but neglected public health threat, affecting the health of the poorest populations and imposing substantial costs on public health systems.
Sachin N. Desai+6 more
doaj +3 more sources
Cholera causes significant morbidity and mortality worldwide. For travelers, the risk of developing cholera per month of stay in a developing country is approximately 0.001%-0.01%, and cholera may present as traveler's diarrhea. In the United States, only a poorly tolerated, marginally effective, parenterally administered, phenol-inactivated vaccine is
Stephen B. Calderwood, Edward T. Ryan
semanticscholar +7 more sources
Modern History of Cholera Vaccines and the Pivotal Role of icddr,b. [PDF]
The rapid spread of the seventh cholera pandemic over Asia in the 1960s led to several large field studies that revealed that the traditional injectable cholera vaccines had poor efficacy, which led the World Health Organization (WHO) in the 1970s to ...
Holmgren J.
europepmc +2 more sources
Willingness to pay for oral cholera vaccines in urban Bangladesh. [PDF]
Introduction Cholera is a highly infectious disease and remains a serious public health burden in Bangladesh. The objective of the study was to measure the private demand for oral cholera vaccines (OCV) in Bangladesh and to investigate the key ...
Sarker AR+11 more
europepmc +2 more sources
Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines. [PDF]
Cholera is a severe diarrheal disease caused by the bacterium Vibrio cholerae (V. cholerae) that results in 3–4 million cases globally with 100,000–150,000 deaths reported annually. Mostly confined to developing nations, current strategies to control the
Davitt CJH+12 more
europepmc +2 more sources
Background Cholera still affects millions of people worldwide, especially in lower- and middle-income countries (LMICs). The Global Task Force on Cholera Control (GTFCC) has identified surveillance and oral cholera vaccines as two critical interventions ...
Hanna Trolle+6 more
doaj +2 more sources
The case for ring vaccinations with special consideration of oral cholera vaccines. [PDF]
Ring vaccinations create a zone of immune contacts around a case to prevent further disease transmission and have been successfully employed in the eradication of smallpox and the control of other infections.
Deen J, von Seidlein L.
europepmc +2 more sources