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Cholera, the Current Status of Cholera Vaccines and Recommendations for Travellers [PDF]
Cholera is endemic in approximately 50 countries, primarily in Africa and South and Southeast Asia, and in these areas, it remains a disease associated with poverty.
Giovanni Gabutti +8 more
doaj +6 more sources
An Update on Cholera Immunity and Current and Future Cholera Vaccines [PDF]
Individual resistance to cholera infection and disease depends on both innate host factors and adaptive immunity acquired by a previous infection or vaccination.
Jan Holmgren
doaj +2 more sources
Cholera causes significant morbidity and mortality worldwide. For travelers, the risk of developing cholera per month of stay in a developing country is approximately 0.001%-0.01%, and cholera may present as traveler's diarrhea. In the United States, only a poorly tolerated, marginally effective, parenterally administered, phenol-inactivated vaccine is
Edward T. Ryan, Stephen B. Calderwood
openalex +6 more sources
Oral cholera vaccines and their impact on the global burden of disease [PDF]
With one-third of nations at risk of cholera, we can expect to experience massive, rapidly disseminated, and prolonged cholera outbreaks such as those recently experienced in Yemen and Haiti.
Thomas F. Wierzba
doaj +2 more sources
Allocation of Oral Cholera Vaccines in Africa [PDF]
Objectives: In this study, we examine the allocation of oral cholera vaccines (OCVs) across 25 African countries between 2013 and 2019. Methods: We constructed a dataset combining cholera outbreaks and requests, decisions, and deliveries of OCVs from the
Elisa M. Maffioli, Yutong Lu
doaj +2 more sources
Oral killed cholera vaccines for preventing cholera. [PDF]
Cholera causes acute watery diarrhoea and death if not properly treated. Outbreaks occur in areas with poor sanitation, including refugee camps. Several vaccines have been developed and tested over the last 50 years. This is an update of a Cochrane review, originally published in 1998, which explored the effects of all vaccines for preventing cholera ...
Saif-Ur-Rahman KM +4 more
europepmc +3 more sources
Prospective observational studies to provide confidence in the protection conferred by newer generation, inactivated oral cholera vaccines: a proposal [PDF]
Summary: Inactivated oral cholera vaccines (OCVs) are a cornerstone of international efforts to control cholera, and are currently deployed from a global stockpile for the control of epidemics and endemic hotspots, as well as for humanitarian emergencies.
John Clemens +2 more
doaj +2 more sources
Achievements and challenges for the use of killed oral cholera vaccines in the global stockpile era [PDF]
Cholera remains an important but neglected public health threat, affecting the health of the poorest populations and imposing substantial costs on public health systems.
Sachin N. Desai +6 more
doaj +2 more sources
Plant-based edible vaccines: Can cholera be the case study in Africa? [PDF]
Vaccines are employed as a sanitary approach that is implemented to lessen the hurdles caused by infectious diseases on the safety of public health. A vaccine is biologically made from inactive components of microbes, to enhance immunity and as a defense
Beenzu Siamalube +5 more
doaj +2 more sources

