An Update on Cholera Immunity and Current and Future Cholera Vaccines [PDF]
Tropical Medicine and Infectious Disease, 2021 Individual resistance to cholera infection and disease depends on both innate host factors and adaptive immunity acquired by a previous infection or vaccination.
Jan Holmgren
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Cholera, the Current Status of Cholera Vaccines and Recommendations for Travellers [PDF]
Vaccines, 2020 Cholera is endemic in approximately 50 countries, primarily in Africa and South and Southeast Asia, and in these areas, it remains a disease associated with poverty.
Giovanni Gabutti +8 more
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Oral cholera vaccines and their impact on the global burden of disease [PDF]
Human Vaccines & Immunotherapeutics, 2019 With one-third of nations at risk of cholera, we can expect to experience massive, rapidly disseminated, and prolonged cholera outbreaks such as those recently experienced in Yemen and Haiti.
Thomas F. Wierzba
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Allocation of Oral Cholera Vaccines in Africa [PDF]
VaccinesObjectives: In this study, we examine the allocation of oral cholera vaccines (OCVs) across 25 African countries between 2013 and 2019. Methods: We constructed a dataset combining cholera outbreaks and requests, decisions, and deliveries of OCVs from the
Elisa M. Maffioli, Yutong Lu
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Prospective observational studies to provide confidence in the protection conferred by newer generation, inactivated oral cholera vaccines: a proposal [PDF]
EClinicalMedicineSummary: Inactivated oral cholera vaccines (OCVs) are a cornerstone of international efforts to control cholera, and are currently deployed from a global stockpile for the control of epidemics and endemic hotspots, as well as for humanitarian emergencies.
John Clemens +2 more
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Achievements and challenges for the use of killed oral cholera vaccines in the global stockpile era [PDF]
Human Vaccines & Immunotherapeutics, 2017 Cholera remains an important but neglected public health threat, affecting the health of the poorest populations and imposing substantial costs on public health systems.
Sachin N. Desai +6 more
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Oral killed cholera vaccines for preventing cholera. [PDF]
Cochrane Database Syst RevCholera causes acute watery diarrhoea and death if not properly treated. Outbreaks occur in areas with poor sanitation, including refugee camps. Several vaccines have been developed and tested over the last 50 years. This is an update of a Cochrane review, originally published in 1998, which explored the effects of all vaccines for preventing cholera ...
Saif-Ur-Rahman KM +4 more
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Uptake likelihood assessment of oral cholera vaccine capsules: insights from stakeholder consultations in five countries [PDF]
BMC Public HealthBackground The global resurgence of cholera, a diarrhoeal disease, has resulted in vaccine demand that exceeds the currently available supply resulting in global calls for next generation cholera vaccines.
Dijana Spasenoska +6 more
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Plant-based edible vaccines: Can cholera be the case study in Africa? [PDF]
Journal of Genetic Engineering and BiotechnologyVaccines are employed as a sanitary approach that is implemented to lessen the hurdles caused by infectious diseases on the safety of public health. A vaccine is biologically made from inactive components of microbes, to enhance immunity and as a defense
Beenzu Siamalube +5 more
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Systemic, Mucosal, and Memory Immune Responses following Cholera
Tropical Medicine and Infectious Disease, 2021 Vibrio cholerae O1, the major causative agent of cholera, remains a significant public health threat. Although there are available vaccines for cholera, the protection provided by killed whole-cell cholera vaccines in young children is poor.
Edward T. Ryan +11 more
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