Heterologous prime-boost-boost immunisation of Chinese cynomolgus macaques using DNA and recombinant poxvirus vectors expressing HIV-1 virus-like particles [PDF]
Background: There is renewed interest in the development of poxvirus vector-based HIV vaccines due to the protective effect observed with repeated recombinant canarypox priming with gp120 boosting in the recent Thai placebo-controlled trial.
Anson, Donald S.+9 more
core +4 more sources
Production of putative enhanced oral cholera vaccine strains that express toxin-coregulated pilus. [PDF]
The use of whole cell killed (WCK) oral cholera vaccines is an important strategy for cholera prevention in endemic areas. To overcome current vaccine limitations, we engineered strains of V.
Caitlyn A Hauke, Ronald K Taylor
doaj +1 more source
The effectiveness of public health interventions to reduce the health impact of climate change:a systematic review of systematic reviews [PDF]
Climate change is likely to be one of the most important threats to public health in the coming years. Yet despite the large number of papers considering the health impact of climate change, few have considered what public health interventions may be of ...
A Bouchama+67 more
core +8 more sources
The influence of immunomodulators on the formation of vaccine-induced cholera immunity
Introduction. Due to the remaining tense situation on cholera in the world, research continues on the creation of new preventive drugs, as well as ways to increase the immunogenicity of existing anti-cholera vaccines.
A. V. Filippenko+3 more
doaj +1 more source
Re-emergence of Cholera Vaccine [PDF]
Although epidemic cholera was first described in 1817, the disease probably has been common in the Indian subcontinent since ancient times.1 Until recently, a single bacterial type (Vibrio cholerae 01) has been responsible for each of the seven recorded cholera pandemics.
Stephen A. Berger, Itzhak Shapiro
openaire +3 more sources
Diagnosis, Management, and Future Control of Cholera
Cholera, caused by Vibrio cholerae, persists in developing countries due to inadequate access to safe water, sanitation, and hygiene. There are approximately 4 million cases and 143,000 deaths each year due to cholera.
F. Chowdhury+4 more
semanticscholar +1 more source
Wanted, an Anthrax vaccine: Dead or Alive? [PDF]
It has been more than 100 years since the realization that microbes are capable of causing disease. In that time, we have learned a great deal as to how each organism has adapted to the immune system so as to avoid elimination.
Smith, Kendall A
core +2 more sources
The Hajj 2019 Vaccine Requirements and Possible New Challenges [PDF]
Each year millions of pilgrims perform the annual Hajj from more than 180 countries around the world. This is one of the largest mass gathering events and may result in the occurrence and spread of infectious diseases.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core +1 more source
India enjoyed early initial successes in vaccine development and indigenous production of vaccines in the public sector.
Bhargava+8 more
core +3 more sources
Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]
Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Barclay WR+8 more
core +1 more source