Results 51 to 60 of about 16,673 (222)

Developing downstream processes for the purification of recombinant proteins and small molecules from Nicotiana benthamiana biomass

Plant Biotechnology Journal, EarlyView.
Summary Nicotiana benthamiana (Australian tobacco) has become a major host for plant‐based recombinant protein production, especially using transient expression. Once a candidate protein has been designed and produced in a suitable variety (e.g. facilitated humanized glycosylation) under reproducible conditions (e.g.
J. F. Buyel
wiley   +1 more source

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim, Andy Cano Tran, Ju Kim, Humblenoble Stembridge Ayuk, Adam Sparrow, Lorenzo Bossi, Megan Brown, Emil Joseph Vergara, Kathrin Göritzer, Elisabetta Groppelli, Tae‐Ho Kwon, Julian K. C. Ma, Yong‐Suk Jang, Rajko Reljic   +13 more
wiley   +1 more source

The State of Public Health in Somalia: Top 5 Challenges and Strategies for Improvement

Public Health Challenges, Volume 4, Issue 4, December 2025.
Somalia's public health system is severely strained by five interconnected challenges: inadequate WASH infrastructure, widespread malnutrition and food insecurity, high burden of infectious diseases, critical gaps in maternal and child health, and the rising prevalence of noncommunicable diseases (NCDs).
Yusuf Hared Abdi, Mohamed Sharif Abdi, Sharmake Gaiye Bashir, Naima Ibrahim Ahmed, Yakub Burhan Abdullahi   +4 more
wiley   +1 more source

Design, synthesis and determination of physical and chemical characteristics of glycoconjugates as model for oligosaccharide vaccines against vibrio cholerae [PDF]

Makedonsko Farmacevtski Bilten, 2003
Cholera is toxin-mediated enteroinfection, with epidemic character and there are approximately 120000 death cases per year worldwide. Protection against cholera has not been accomplished due to deficiencies in the licensed vaccines.
Aleksandra Grozdanova, Ana Poceva, Katerina Milenkova, Ljubica Suturkova   +3 more
doaj  

Reimagining Social Value to Consider the Environment: How Should We Judge the Magnitude of Benefits in Health Research?

Bioethics, Volume 39, Issue 9, Page 821-833, November 2025.
ABSTRACT Growing recognition of intersections between our health and the environment, healthcare systems and the environment, and health research and the environment has led bioethics scholars to advocate that the field readopt a broader perspective that considers nature.
Bridget Pratt, Rieke van der Graaf
wiley   +1 more source

Review of oral cholera vaccines: efficacy in young children

Infection and Drug Resistance, 2011
Cristina Masuet Aumatell1, JM Ramon Torrell1, Jane N Zuckerman21International Health Centre, Preventive Medicine Department, Bellvitge Hospital, L'Hospitalet de Llobregat, Barcelona, Spain; 2World Health Organization Collaborating Centre for ...
Masuet Aumatell C, Ramon Torrell JM, Zuckerman JN   +2 more
doaj  

Use of oral cholera vaccine as a vaccine probe to define the geographical dimensions of person-to-person transmission of cholera

International Journal of Infectious Diseases, 2018
Background: Cholera is known to be transmitted from person to person, and inactivated oral cholera vaccines (OCVs) have been shown to confer herd protection via interruption of this transmission.
Mohammad Ali, Deok Ryun Kim, Suman Kanungo, Dipika Sur, Byomkesh Manna, Laura Digilio, Shanta Dutta, Florian Marks, Sujit K. Bhattacharya, John Clemens   +9 more
doaj   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Tackling Cholera Outbreak Amidst COVID-19 Pandemic in Nigeria: Challenges and Recommendations

Public Health Reviews, 2022
Background: Since the first confirmed case of the Novel Coronavirus Disease 2019 (COVID-19) in Nigeria, the pandemic has become a major public health challenge, affecting different sectors of the country.
Alhaji Umar Sow, Usman Abubakar Haruna, Usman Abubakar Haruna, Oladunni Abimbola Amos, Oladunni Abimbola Amos, Edward Olorunfemi Olajide, Terhemen Amene, Oluwatomisin Dara Odususi, Bukola Adedoyin Adewusi, Chinedu Abia, Jackson Safari, Florence Wuraola Sorinola, Hassan Olayemi Alaka, Sulaiman Muhammad Musa   +13 more
doaj   +1 more source

Cancer in pregnancy: FIGO Best practice advice and narrative review

International Journal of Gynecology &Obstetrics, Volume 171, Issue 1, Page 131-151, October 2025.
Abstract Cancer during pregnancy is relatively rare. The incidence is underestimated due to the lack of international registries covering both high‐income and low‐ and middle‐income countries, and is expected to rise with increasing maternal age and increasing global adoption of cell‐free DNA testing for aneuploidy.
Surabhi Nanda, Melanie Nana, Long Nguyen‐Hoang, Sumaiya Adam, Fionnuala McAuliffe, Lina Bergman, Sarikapan Wilailak, Orla McNally, Cynthia V. Maxwell, Nikhil Purandare, Bo Jacobsson, Virna P. Medina, Anil Kapur, Titus Beyuo, Francisco Ruiloba, Ernesto Castelazo, Graeme N. Smith, Sharleen L. O'Reilly, Patrick O'Brien, Mark Hanson, Mary L. Rosser, Claudio Sosa, Valerie Guinto, Jonathan Berek, Catherine Nelson‐Piercy, Frédéric Amant, Liona Poon, on behalf of the FIGO Committee on the Impact of Pregnancy on Long‐term Health, FIGO Committee on Women's Cancer, and the FIGO Division of Maternal and Newborn Health   +29 more
wiley   +1 more source