Empirical Chiroptical Analyses of Vicinal Bromochloro Natural Products by van't Hoff's Principle of Optical Superposition: Assignment of the C-16 Configurations of Callophycols A and B. [PDF]
J Org ChemA simple empirical method is described that allows the assignment of absolute configurations of natural products containing chiral vicinal bromochloro (VBC) units, including the bromochloro substituted isoprenyl units present in the structures of ...
Molinski TF.
europepmc +3 more sources
Vendozoa and selective forces on animal origin and early diversification: reply to Dufour and McIlroy (2017). [PDF]
Philos Trans R Soc Lond B Biol Sci, 2018 Cavalier-Smith T.
europepmc +3 more sources
6-Hydroxyimino-5α-cholestane [PDF]
Acta Crystallographica Section E Structure Reports Online, 2012 The title compound, C(27)H(47)NO, is a steroid derivative composed of a saturated carbon fused-ring framework with an alkyl side chain. Ring bond lengths have normal values with an average of 1.533 (2) Å, while the cholestane side chain shows an average bond length of 1.533 (2) Å.
Uzzaman, Shams +4 more
openaire +2 more sources
Towards the synthesis of calotropin and related cardenolides from 3-epiandrosterone : A-ring related modifications [PDF]
, 2020 Calotropin and related cardiac glycosides isolated from plants such ascalotropis gigantearepresent an interesting target for biological investigations and are based on a cardiac steroid that is doubly connected to a sugar moiety. This naturally occurring
Bräse, Stefan +2 more
core +4 more sources
Stereoselective synthesis of perhydrobenzo[4.5.6]cholestanes [PDF]
, 1992 An intramolecular Michael-aldol reaction sequence has been developed for the stereocontrolled synthesis of pentacyclic steroids! with the new six-membered ring attached to the C(4) and C(6) positions. Cholesterol was converted into 3β-hydroxycholest-4-en-6-one by standard methods, and the corresponding 3α-isomer was obtained through Mitsunobu inversion.
Borry, Joost
openaire +3 more sources
Chemical Composition and Physical Properties of “Pale Yellow” Naphtalan [PDF]
, 2011 The Pale Yellow (PY) Naphthalan is potentially a new treatment modality for some oral mucosal and dermatological diseases. Its chemical composition and physical properties were studied by standard and sophisticated methods.
Anđa Alajbeg +6 more
core +2 more sources
Mass spectrometric analysis of epimeric 3α/3β functionalized steroids. [PDF]
, 2007 Tandem mass spectrometry (MS/MS) using an atmospheric pressure chemical ionization (APCI) source in positive mode (+) reveals different intensity ratios of two fragment peaks of the epimeric cholestane derivatives synthesized from 3{460}- or 3β ...
Almeida, Paulo +5 more
core +1 more source
Arylmethylamino steroids as antiparasitic agents [PDF]
, 2017 In search of antiparasitic agents, we here identify arylmethylamino steroids as potent compounds and characterize more than 60 derivatives. The lead compound 1o is fast acting and highly active against intraerythrocytic stages of chloroquine-sensitive ...
Becker, Katja +19 more
core +3 more sources
Cholestane Glycosides from Solanum abutiloides. III.
Chemical and Pharmaceutical Bulletin, 2000 Four new cholestane glycosides, named abutilosides D (1), E (2), F (3) and G (4), were isolated from the fresh roots of Solanum abutiloides. By chemical and spectroscopic evidence, their structures were elucidated as 26-O-beta-D-glucopyranosyl 3beta,16alpha,26-trihydroxy-5alpha-cholestan-22-one 3-O-beta-D-xylopyranosyl-(1-->2)-alpha-L-rhamnopyranosyl ...
H, Yoshimitsu, M, Nishida, T, Nohara
openaire +5 more sources
Chemistry and properties of perhydrobenzo[4.5.6]cholestanes [PDF]
, 2023 The investigations undertaken include an intramolecular Michael-aldol approach and a cycloaddition approach to the synthesis ofperhydrobe,nzo[4.5.6]cholestanes. A reaction sequence has been developed to obtain the 3 P-acetoxy-4cx.,5cx. - dihydrobenzo [ 4.
Mohamed, Camielah
core +1 more source