Results 131 to 140 of about 1,835 (170)
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Prevention of Cholestanol-induced Cholelithiasis by Neomycin
Nature, 1965RABBITS receiving 0.25–1 per cent dietary cholestanol (5α-cholestan-3β-ol) for 3–6 weeks develop gall-stones which have been shown to consist predominantly of calcium, and sodium glycoallodeoxycholate (3α-, 12α-dihydroxy-5α-cholanoyl glycine)1,2. Gall-stone formation in cholestanol-fed rabbits has been postulated to occur as follows: Cholestanol is ...
E H, Mosbach +5 more
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Analysis of sterol extracts for cholestanol
Analytical Biochemistry, 1965Abstract Cholestanol analyses of sterols have been carried out by removal of the unsaturated sterols by oxidation and extraction followed by gas chromatography of the saturated sterols. The method can detect 0.2% of cholestanol in sterol mixtures.
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Cholestanol Induces Apoptosis of Cerebellar Neuronal Cells
Biochemical and Biophysical Research Communications, 1999Cerebrotendinous xanthomatosis (CTX) is a hereditary lipid storage disease characterized by hyper-cholestanolemia, cerebellar ataxia, xanthoma, and cataract. We hypothesized that cholestanol in serum of CTX patients might induce neuronal cell death in the cerebellum and eventually lead to cerebellar ataxia.
K, Inoue, S, Kubota, Y, Seyama
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Association of cholestanol and cholestanone with lysophosphatidylcholine
Chemistry and Physics of Lipids, 1984Abstract On sonication in water, cholestanol and lysophosphatidylcholine (lysoPC) in 1:1 molar ratio form unilamellar vesicles which are similar to lysoPC/cholesterol vesicles, as judged by gel exclusion chromatography, electron microscopy, and differential thermal scanning.
L.S. Ramsammy, P.A. Merz, H. Brockerhoff
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Cholestanol and plant sterols in pigeon skin
Lipids, 1973AbstractCholestanol (4.6%) and plant sterols (0.2%) have been demonstrated, for the first time, in avian skin by argentation and gas liquid chromatography. In contrast to results of previous studies with rat and human skin, cholestanol represented a significant amount in the pigeon.
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Effect of Vagotomy on Cholestanol Cholelithogenesis in the Rabbit
Investigative Radiology, 1968The effect of bilateral truncal vagotomy on the gallbladder of the rabbit was studied. Up to twenty-four weeks, no significant spontaneous cholelithogenesis appeared. When vagotomized rabbits were given sublithogenic doses of cholestanol, gallstones formed in 50%.
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Cholestanol-Induced Gallstones: Radiologic Observations
Radiology, 1967Gallstones can be reliably induced in rabbits by the addition of 3-beta-cholestanol to an otherwise normal diet. This initial observation of Bevans and Mosbach (2) has been confirmed by others (3, 6, 8) and has been found to be a useful experimental model.
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Plasma Esterification of Cholestanol, Normally and in Cerebrotendinous Xanthomatosis
Scandinavian Journal of Clinical and Laboratory Investigation, 1974In vitro esterification of labeled cholestanol was demonstrated in normal plasma as well as in plasma from patients with cerebrotendinous xanthomatosis, the rate of esterification being about 70 per cent of that of cholesterol. In familial lecithin:cholesterol acyltransferase (LCAT) deficiency no esterification either of cholesterol or of cholestanol ...
S, Skrede, K T, Stokke
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Studies on the biosynthesis of cholestanol in cultured cells.
Journal of biochemistry, 1983The presence of cholestanol had never been reported in cultured cells, but in the present study cholestanol was detected both in human and rat skin fibroblasts. The present study has shown that the origin of cholestanol in these fibroblasts was derived from de novo synthesis in the cells rather than from the fetal calf serum used in the growth medium ...
S, Serizawa +3 more
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