Results 91 to 100 of about 27,709 (227)
Risk Factors for Immediate and Delayed-Onset Fever After Percutaneous Transhepatic Biliary Drainage [PDF]
Objectives To prospectively investigate the pre and intraprocedural risk factors for immediate (IF) and delayedonset (DOF) fever development after percutaneous transhepatic biliary drainage (PTBD).
Bezzi, Mario +10 more
core +1 more source
Hepatobiliary transport systems mediate hepatic uptake and biliary excretion of bile acids, bilirubin and other biliary constituents. Hereditary or acquired defects of these transporters may cause or maintain cholestasis and jaundice under various ...
Martin Wagner, Michael Trauner
doaj +1 more source
ABSTRACT Endoscopic biliary drainage for malignant hilar biliary obstruction is technically demanding especially when multiple ducts require drainage. Plastic inside stents are widely used because of their removability and ease of exchange, but multiple insertion is often hindered by stent interference.
Akinobu Koiwai +9 more
wiley +1 more source
Hereditäre Defekte hepatobiliärer Transportproteine [PDF]
Zusammenfassung: Eine gestörte Funktion hepatobiliärer Transportproteine kann zu schweren hereditären cholestatischen Leberkrankheiten führen. Die progressive familiäre intrahepatische Cholestase (PFIC) manifestiert sich im frühen Kindesalter.
Kullak-Ublick, G.A., Mwinyi, J.
core
PXR-mediated Metabolism During Pregnancy and Cholestasis
Nuclear receptors, including the pregnane x receptor (PXR) and the farnesoid x receptor (FXR), regulate the expression of genes that maintain bile acid (BA) homeostasis. Intrahepatic cholestasis of pregnancy (ICP) is a common gestational liver disease
Owen, Bryn Myers, Owen, Bryn Myers
core +1 more source
ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth [PDF]
Epigenetic silencing through promoter hypermethylation is an important hallmark for the inactivation of tumor-related genes in carcinogenesis. Here we identified the ATP-binding cassette sub-family B member 4 (ABCB4) as a novel epigenetically silenced ...
Dammann, Reinhard H. +7 more
core +1 more source
RNA‐Based Therapies for Inherited Metabolic Disorders
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri +5 more
wiley +1 more source
Primary biliary cirrhosis in a rheumatoid arthritis patient treated with rituximab, a case-based review [PDF]
Primary biliary cirrhosis (PBC) is an autoimmune disease in which intrahepatic bile ducts are targeted by an immune-mediated injury. This disease tends to progress to fibrosis and cirrhosis with hepatic failure. The authors report a case of a 50-year-old
Canhão, H +5 more
core +1 more source
ABSTRACT Objective A comprehensive review of maternal, obstetric and neonatal outcomes in pregnancies in females with cystic fibrosis (fwCF) following the introduction of Elexacaftor/Tezacaftor/Ivacaftor (ETI) therapy in a novel, dedicated CF‐Maternal Health service.
Rebecca Scott +12 more
wiley +1 more source

