Results 91 to 100 of about 27,709 (227)

Risk Factors for Immediate and Delayed-Onset Fever After Percutaneous Transhepatic Biliary Drainage [PDF]

open access: yes, 2015
Objectives To prospectively investigate the pre and intraprocedural risk factors for immediate (IF) and delayedonset (DOF) fever development after percutaneous transhepatic biliary drainage (PTBD).
Bezzi, Mario   +10 more
core   +1 more source

Transcriptional regulation of hepatobiliary transport systems in health and disease: Implications for a rationale approach to the treatment of intrahepatic cholestasis

open access: yesAnnals of Hepatology, 2005
Hepatobiliary transport systems mediate hepatic uptake and biliary excretion of bile acids, bilirubin and other biliary constituents. Hereditary or acquired defects of these transporters may cause or maintain cholestasis and jaundice under various ...
Martin Wagner, Michael Trauner
doaj   +1 more source

Simultaneous Placement of Three Thin‐Delivery Multi‐Hole Self‐Expandable Metallic Stents for Malignant Hilar Biliary Obstruction Using a Large‐Channel Duodenoscope

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Endoscopic biliary drainage for malignant hilar biliary obstruction is technically demanding especially when multiple ducts require drainage. Plastic inside stents are widely used because of their removability and ease of exchange, but multiple insertion is often hindered by stent interference.
Akinobu Koiwai   +9 more
wiley   +1 more source

Hereditäre Defekte hepatobiliärer Transportproteine [PDF]

open access: yes, 2018
Zusammenfassung: Eine gestörte Funktion hepatobiliärer Transportproteine kann zu schweren hereditären cholestatischen Leberkrankheiten führen. Die progressive familiäre intrahepatische Cholestase (PFIC) manifestiert sich im frühen Kindesalter.
Kullak-Ublick, G.A., Mwinyi, J.
core  

PXR-mediated Metabolism During Pregnancy and Cholestasis

open access: yes, 2009
Nuclear receptors, including the pregnane x receptor (PXR) and the farnesoid x receptor (FXR), regulate the expression of genes that maintain bile acid (BA) homeostasis. Intrahepatic cholestasis of pregnancy (ICP) is a common gestational liver disease
Owen, Bryn Myers, Owen, Bryn Myers
core   +1 more source

ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth [PDF]

open access: yes, 2014
Epigenetic silencing through promoter hypermethylation is an important hallmark for the inactivation of tumor-related genes in carcinogenesis. Here we identified the ATP-binding cassette sub-family B member 4 (ABCB4) as a novel epigenetically silenced ...
Dammann, Reinhard H.   +7 more
core   +1 more source

RNA‐Based Therapies for Inherited Metabolic Disorders

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri   +5 more
wiley   +1 more source

Primary biliary cirrhosis in a rheumatoid arthritis patient treated with rituximab, a case-based review [PDF]

open access: yes, 2011
Primary biliary cirrhosis (PBC) is an autoimmune disease in which intrahepatic bile ducts are targeted by an immune-mediated injury. This disease tends to progress to fibrosis and cirrhosis with hepatic failure. The authors report a case of a 50-year-old
Canhão, H   +5 more
core   +1 more source

Obstetric and Neonatal Outcomes in Pregnancies From a Dedicated Cystic Fibrosis‐Maternal Health Service: A Retrospective Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 690-697, March 2026.
ABSTRACT Objective A comprehensive review of maternal, obstetric and neonatal outcomes in pregnancies in females with cystic fibrosis (fwCF) following the introduction of Elexacaftor/Tezacaftor/Ivacaftor (ETI) therapy in a novel, dedicated CF‐Maternal Health service.
Rebecca Scott   +12 more
wiley   +1 more source

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