Results 121 to 130 of about 27,709 (227)

DOCK8 deficiency presenting with sclerosing cholangitis, raised immunoglobulin E, and bronchiectasis: A fatal pediatric case report

JPGN Reports, Volume 7, Issue 1, Page 11-13, February 2026.
Abstract Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive primary immunodeficiency. Patients with DOCK8 deficiency typically present at early age with allergic manifestations, cutaneous and respiratory infections, raised immunoglobulin E, and they have an increased risk of developing malignancies.
Natalia Nedelkopoulou, Kelechi Ugonna, Stephen Hughes, Sanjay Rajwal, Marumbo Mtegha   +4 more
wiley   +1 more source

A rare case of pediatric autoimmune pancreatitis and autoimmune hepatitis in a patient with sickle cell disease

JPGN Reports, Volume 7, Issue 1, Page 142-146, February 2026.
Abstract Concurrent pediatric autoimmune pancreatitis (AIP) and autoimmune hepatitis (AIH) are rarely reported, and no established pediatric‐specific guidelines are available to guide the diagnosis and management of these conditions in children. While AIP and AIH share an underlying autoimmune mechanism of injury, marked by chronic inflammatory changes
Sasha‐Jane Abi‐Aad, Michelle Edward, David Germain, Rene Gomez‐Esquivel, Racha Khalaf   +4 more
wiley   +1 more source

Maralixibat for the treatment of severe xanthomas in two children with Alagille syndrome: Case reports

JPGN Reports, Volume 7, Issue 1, Page 1-5, February 2026.
Abstract Alagille syndrome (ALGS) is a rare, autosomal dominant disorder which presents with a broad range of clinical manifestations, including cholestatic pruritus. A unique manifestation of ALGS is the presence of xanthomas in 24%–42% of patients, which can lead to liver transplantation.
Geetanjali Bora, Ruben E. Quiros‐Tejeira, Bernadette Vitola   +2 more
wiley   +1 more source

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu, Ziyuan Wang, Huirong Zhu, Yicun Han, Qing Ji   +4 more
wiley   +1 more source

Are Postprandial Bile Acid Levels Helpful in Predicting Perinatal Complications in Patients with Intrahepatic Cholestasis of Pregnancy?

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015
Purpose: To determine the outcomes of Iintrahepatic cholestasis of pregnancy and the role of postprandial serum bile acid levels in the prediction of perinatal complications.
Kudret Erkenekli, Can Tekin iskender, Hasan Onur Topcu, Tugba Ensari, Dilek Uygur, Nuri Danisman   +5 more
doaj  

Higher Risk of Serious Infection in Offspring of Mothers With Biopsy‐Proven MASLD: A Nationwide Cohort Study

United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) has been linked to an increased risk of serious infection, but the impact of in utero exposure to maternal MASLD on the risk of infection in offspring remains unknown.
Carole A. Marxer, Fahim Ebrahimi, David Bergman, Jiangwei Sun, Hannes Hagström, Marcus Thuresson, Olof Stephansson, Jonas F. Ludvigsson   +7 more
wiley   +1 more source

Nutritional approach in a growing Jack Russell terrier with gall bladder agenesis

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract An asymptomatic male Jack Russell terrier diagnosed at the age of 18 weeks with congenital gall bladder agenesis, confirmed by computed tomography scan, after finding abnormally high values for liver enzymes in a routine blood count. Treatment with liver‐protective agents S‐adenosylmethionine and ursodeoxycholic acid was initiated. At 6 months
Tamara Seghers, Matthias Dennler, Brigitta Wichert, Annette Liesegang   +3 more
wiley   +1 more source

Cholecystitis & An Enzyme Study [PDF]

, 2011
Cholecystitis is inflammation of the gallbladder that develops in short time usually when gallstone obstructs the cystic duct. Patients over the passage of time land to chronic cholecystitis.
Anil Batta, Int J Cur Biomed Phar Res.
core  

Soluble CD163 as a Biomarker of Liver Fibrosis and Inflammation in Liver Transplant Recipients

Clinical Transplantation, Volume 40, Issue 2, February 2026.
ABSTRACT Background and Aims Post liver transplantation (LT) inflammation and fibrosis are clinical challenges that may affect long‐term outcomes. We aimed to investigate sCD163 as a biomarker of liver fibrosis in LT recipients and compare it with the Fibrosis 4 (FIB‐4) score and FibroScan.
Emilie Høegholm Ernst Lauridsen, Rasmus Hvidbjerg Gantzel, Moises Alberto Suarez‐Zdunek, Mette Bak Nielsen, Allan Rasmussen, Susanne Dam Nielsen, Henning Grønbæk, Gerda Elisabeth Villadsen   +7 more
wiley   +1 more source

Can ammonia scavenging treat MASLD? Evaluating the evidence for L‐ornithine L‐aspartate—A systematic review

European Journal of Clinical Investigation, Volume 56, Issue 2, February 2026.
Abstract Introduction While hyperammonemia is traditionally associated with decompensated cirrhosis, emerging evidence suggests that disturbances in nitrogen homeostasis contribute to disease progression in earlier stages of steatohepatitis and fibrosis.
Abdulrahman Ismaiel, Vera Ciornolutchii, Stefan‐Lucian Popa, Dan L. Dumitrascu   +3 more
wiley   +1 more source