Results 1 to 10 of about 1,802,229 (363)

Impact of Cholesterol on Voids in Phospholipid Membranes [PDF]

, 2004
Free volume pockets or voids are important to many biological processes in cell membranes. Free volume fluctuations are a prerequisite for diffusion of lipids and other macromolecules in lipid bilayers. Permeation of small solutes across a membrane, as well as diffusion of solutes in the membrane interior are further examples of phenomena where voids ...
Almeida, Bassolino-Klimas, Bassolino-Klimas, Bemporad, Berendsen, Berger, Bloom, Bondi, Cantor, Chiu, Cohen, de Jeu, Eckenhoff, Essman, Falck, Galla, Hofsäß, Hoshen, Höltje, Jedlovszky, Jedlovszky, Kaznessis, Lindahl, Loison, Marrink, Marrink, Marrink, Mathai, McConnell, Mitragotri, Nagle, Newman, Patra, Patra, Polson, Pralle, Rajagopal, Repáková, Róg, Shinoda, Smondyrev, Tieleman, Vist, Xiang   +43 more
arxiv   +3 more sources

Small Dense LDL: Scientific Background, Clinical Relevance, and Recent Evidence Still a Risk Even with ‘Normal’ LDL-C Levels

Biomedicines, 2022
Residual cardiovascular disease event risk, following statin use and low-density lipoprotein cholesterol (LDL-C) reduction, remains an important and common medical conundrum.
Harold Superko, Brenda Garrett
doaj   +1 more source

Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

Signal Transduction and Targeted Therapy, 2022
Disturbed cholesterol homeostasis plays critical roles in the development of multiple diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and cancers, particularly the CVD in which the accumulation of lipids (mainly the ...
Yajun Duan, Ke Gong, Suowen Xu, Feng Zhang, Xian Meng, Jihong Han   +5 more
semanticscholar   +1 more source

Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles

Journal of Extracellular Vesicles, 2022
Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes.
Michel Record, Mehdi Attia, Kevin Carayon, Laly Pucheu, Julio Bunay, Régis Soulès, Silia Ayadi, Bruno Payré, Laure Perrin‐Cocon, Florence Bourgailh, Antonin Lamazière, Vincent Lotteau, Marc Poirot, Sandrine Silvente‐Poirot, Philippe de Medina   +14 more
doaj   +1 more source

Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol

Frontiers in Bioengineering and Biotechnology, 2021
Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a hydrophilic head constituting a phospholipid membrane. The spherical or multilayered spherical structures of liposomes are highly rich in lipid contents with ...
Pooria Nakhaei, Ria Margiana, Dmitry O. Bokov, Walid Kamal, Mohammad Amin Jadidi Kouhbanani, R. Varma, F. Marofi, M. Jarahian, Nasrin Beheshtkhoo   +8 more
semanticscholar   +1 more source

Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.

Clinical Chemistry, 1972
A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-density lipoprotein cholesterol ...
W. T. Friedewald, R. Levy, D. Fredrickson   +2 more
semanticscholar   +1 more source

Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster [PDF]

, 2004
BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to ...
Contos, Linda M, Deck, Lorraine M, Heidrich, John E, Hunsaker, Lucy A, Vander Jagt, David L   +4 more
core   +2 more sources

Association between cholesterol-phospholipid vesicles and cholesterol crystals in human gallbladder bile [PDF]

, 1989
Rapid aggregation of cholesterol-phospholipid vesicles in gallbladder bile seems to be the first event in the production of cholesterol crystals, a prerequisite for cholesterol gallstone formation.
Jüngst, Dieter, Schriever, Carolin Erika   +1 more
core   +1 more source

A randomized controlled trial to evaluate the effects of high Protein Complete (lActo) VEgetaRian (PACER) diet in non-diabetic obese Asian Indians in North India

Heliyon, 2017
In view of the increasing prevalence of obesity in largely vegetarian Asian Indians, it is important to research a high protein, low carbohydrate vegetarian diet.
Swati Bhardwaj, Anoop Misra, Seema Gulati, Shajith Anoop, Vineet Kumar Kamal, Ravindra Mohan Pandey   +5 more
doaj   +1 more source

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.

Journal of Clinical Investigation, 2002
Lipid homeostasis in vertebrate cells is regulated by a family of membrane-bound transcription factors designated sterol regulatory element–binding proteins (SREBPs).
J. Horton, J. Goldstein, Michael S. Brown   +2 more
semanticscholar   +1 more source