Results 1 to 10 of about 2,069,563 (390)

Small Dense LDL: Scientific Background, Clinical Relevance, and Recent Evidence Still a Risk Even with ‘Normal’ LDL-C Levels

Biomedicines, 2022
Residual cardiovascular disease event risk, following statin use and low-density lipoprotein cholesterol (LDL-C) reduction, remains an important and common medical conundrum.
Harold Superko, Brenda Garrett
doaj   +1 more source

Cholesterol Pericarditis

JACC: Case Reports, 2022
Cholesterol pericarditis is a rare condition characterized by a large, chronic cholesterol-rich pericardial effusion that often manifests with symptoms of heart failure. We report a case of an asymptomatic 51-year-old man with a massive cholesterol-rich pericardial effusion with echocardiographic evidence of impending tamponade.
Khawaja, Tasveer, Feroze, Rafey, Hoit, Brian D.   +2 more
openaire   +4 more sources

27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor

Journal of Lipid Research, 2023
Oncosterone (6-oxo-cholestane-3β,5α-diol; OCDO) is an oncometabolite and a tumor promoter on estrogen receptor alpha-positive breast cancer (ER(+) BC) and triple-negative breast cancers (TN BC). OCDO is an oxysterol formed in three steps from cholesterol:
Silia Ayadi, Silvia Friedrichs, Regis Soulès, Laly Pucheu, Dieter Lütjohann, Sandrine Silvente-Poirot, Marc Poirot, Philippe de Medina   +7 more
doaj   +1 more source

Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles

Journal of Extracellular Vesicles, 2022
Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes.
Michel Record, Mehdi Attia, Kevin Carayon, Laly Pucheu, Julio Bunay, Régis Soulès, Silia Ayadi, Bruno Payré, Laure Perrin‐Cocon, Florence Bourgailh, Antonin Lamazière, Vincent Lotteau, Marc Poirot, Sandrine Silvente‐Poirot, Philippe de Medina   +14 more
doaj   +1 more source

Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

Signal Transduction and Targeted Therapy, 2022
Disturbed cholesterol homeostasis plays critical roles in the development of multiple diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and cancers, particularly the CVD in which the accumulation of lipids (mainly the ...
Yajun Duan, Ke Gong, Suowen Xu, Feng Zhang, Xian Meng, Jihong Han   +5 more
semanticscholar   +1 more source

A randomized controlled trial to evaluate the effects of high Protein Complete (lActo) VEgetaRian (PACER) diet in non-diabetic obese Asian Indians in North India

Heliyon, 2017
In view of the increasing prevalence of obesity in largely vegetarian Asian Indians, it is important to research a high protein, low carbohydrate vegetarian diet.
Swati Bhardwaj, Anoop Misra, Seema Gulati, Shajith Anoop, Vineet Kumar Kamal, Ravindra Mohan Pandey   +5 more
doaj   +1 more source

Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol

Frontiers in Bioengineering and Biotechnology, 2021
Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a hydrophilic head constituting a phospholipid membrane. The spherical or multilayered spherical structures of liposomes are highly rich in lipid contents with ...
Pooria Nakhaei, Ria Margiana, Dmitry O. Bokov, Walid Kamal, Mohammad Amin Jadidi Kouhbanani, R. Varma, F. Marofi, M. Jarahian, Nasrin Beheshtkhoo   +8 more
semanticscholar   +1 more source

Extracellular vesicles: lipids as key components of their biogenesis and functions

Journal of Lipid Research, 2018
Intercellular communication has been known for decades to involve either direct contact between cells or to operate via circulating molecules, such as cytokines, growth factors, or lipid mediators.
Michel Record, Sandrine Silvente-Poirot, Marc Poirot, MichaelJ.O. Wakelam   +3 more
doaj   +1 more source

A Body shape index significantly predicts MRI-defined abdominal adipose tissue depots in non-obese Asian Indians with type 2 diabetes mellitus

BMJ Open Diabetes Research & Care, 2020
Introduction We aimed to determine the correlations of volumes of subcutaneous abdominal adipose tissue (SCAT) (anterior, posterior, superficial and deep), total SCAT, intraperitoneal adipose tissue, retroperitoneal abdominal adipose tissue (RPAT), total
Shajith Anoop, Jesse Krakauer, Nir Krakauer   +2 more
doaj   +1 more source

Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, India

Journal of Diabetes Research, 2017
Background. We studied the impact of the multicomponent interventions on body weight and cardiometabolic risk factors in overweight individuals working in corporate worksites. Methods.
Usha Shrivastava, Mahrukh Fatma, Smriti Mohan, Padam Singh, Anoop Misra   +4 more
doaj   +1 more source