Results 81 to 90 of about 981,314 (303)

Food intake, nutritional anthropometry and blood chemical parameters in 3 selected Dutch schoolchildren populations [PDF]

open access: yes, 1978
The major health problems in populations of economically developed countries at the present time are of a chronic nature with, as their main clinical characteristic, the frequently occurring premature coronary heart disease.
van der Haar, F.   +2 more
core  

Ahcy Acts as an Effector of Hnf4a‐Driven Super‐Enhancer Activation to Alleviate MASLD During Intermittent Fasting

open access: yesAdvanced Science, EarlyView.
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen   +6 more
wiley   +1 more source

Gender differences in response to dietary soluble fiber in guinea pigs: effects of pectin, guar gum, and psyllium.

open access: yesJournal of Lipid Research, 1996
Dietary soluble fiber significantly lowers plasma low density lipoprotein (LDL) cholesterol concentrations in humans and animals. In male guinea pigs, alterations in hepatic cholesterol homeostasis induced by dietary fiber in part account for the ...
M L Fernandez   +4 more
doaj   +1 more source

Report of the Commission on Dietary Supplement Labels

open access: yes, 1997
Final report of the Commission on Dietary Supplement Labels describing their activities and findings regarding the safety of dietary supplements, including sections on pertinent legislation, consumer use, labeling, and nutritional ...
Commission on Dietary Supplement Labels
core  

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

open access: yesAdvanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu   +4 more
wiley   +1 more source

Urinary cholesterol in cancer screening [PDF]

open access: yes, 1982
Cholesterol determinations in morning urine samples were taken in 235 selected patients with a positive test for microscopic hematuria. Values ranged from 0.2 to 76.0 mg (median 5.5) in 23 patients with urologic malignancies and from 0.1 to 33.4 mg ...
Tauber, Roland   +3 more
core   +1 more source

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

open access: yesAdvanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui   +5 more
wiley   +1 more source

LDL particle size and LDL and HDL cholesterol changes with dietary fat and cholesterol in healthy subjects

open access: yesJournal of Lipid Research, 1998
We have conducted a dietary trial in 54 men and 51 women with a wide range of fasting cholesterol values to examine the use of low density lipoprotein (LDL) particle size to predict the lipoprotein response to dietary fat and cholesterol.
Peter M. Clifton   +2 more
doaj   +1 more source

Epidemiology of coronary heart disease in Asians in Britain [PDF]

open access: yes, 1990
In countries where people of South Asian origin have settled, unexpectedly high coronary heart disease rates have been recorded in South Asian men and women compared with other ethnic groups. In England high CHD mortality is shared by Gujarati Hindus,
McKeigue, PM
core  

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