Results 61 to 70 of about 981,314 (303)

Cholesterol absorption efficiency declines at moderate dietary doses in normal human subjects

Journal of Lipid Research, 1999
While unphysiologically large cholesterol doses are known to reduce percent cholesterol absorption, smaller amounts are reported to have no effect in human subjects.
Richard E. Ostlund, Jr., Matthew S. Bosner, William F. Stenson   +2 more
doaj   +1 more source

Cholesterol nucleation time in gallbladder bile of patients with solitary or multiple cholesterol gallstones [PDF]

, 1992
Patients with multiple cholesterol gallbladder stones have been found to be at a higher risk for the recurrence of gallstones after successful nonsurgical treatment than those with a solitary stone.
Ritter, Christoph von, Paumgartner, Gustav, Pratschke, Ekkehard, Jüngst, Dieter, Lang, Thomas   +4 more
core   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Dietary Cholesterol Supplementation Inhibits the Steroid Biosynthesis but Does Not Affect the Cholesterol Transport in Two Marine Teleosts: A Hepatic Transcriptome Study

Aquaculture Nutrition, 2023
Cholesterol has been used as additive in fish feeds due to the reduced use of fish meal and fish oil. In order to evaluate the effects of dietary cholesterol supplementation (D-CHO-S) on fish physiology, a liver transcriptome analysis was performed ...
Ziling Song, Haiyan Xiong, Xiaoxue Meng, Qiang Ma, Yuliang Wei, Yanlu Li, Jian Liu, Mengqing Liang, Houguo Xu   +8 more
doaj   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

PHYSIOLOGY OF CHOLESTEROL METABOLISM (THE REVIEW)

Acta Biomedica Scientifica, 2012
There are two sources of cholesterol: endogenous (biliary) and exogenous (dietary) in human organism. Biliary cholesterol arrives with cyctic and. hepatic bile in small intestine and. is mixed, with dietary cholesterol.
YA. L. Tyuryumin, V. A. Shanturov, E. E. Tyuryumina   +2 more
doaj  

Dietary Cholesterol and Myocardial Infarction in the Million Veteran Program

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Coronary artery disease is a leading cause of morbidity and mortality in the United States. Coronary artery disease can lead to major complications including myocardial infarction (MI).
Xuan‐Mai T. Nguyen, Yanping Li, Mark S. Nyaeme, Neha Panigrahy, Serena Houghton, Kerry L. Ivey, Shamlan Shiekh, Walter C. Willett, Frank B. Hu, J. Michael Gaziano, Peter W. F. Wilson, Kelly Cho, Luc Djousse   +12 more
doaj   +1 more source

Cholesterol crystallization within hepatocyte lipid droplets and its role in murine NASH[S]

Journal of Lipid Research, 2017
We recently reported that cholesterol crystals form in hepatocyte lipid droplets (LDs) in human and experimental nonalcoholic steatohepatitis. Herein, we assigned WT C57BL/6J mice to a high-fat (15%) diet for 6 months, supplemented with 0%, 0.25%, 0.5 ...
George N. Ioannou, Savitha Subramanian, Alan Chait, W. Geoffrey Haigh, Matthew M. Yeh, Geoffrey C. Farrell, Sum P. Lee, Christopher Savard   +7 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

A Single Meal Containing Phytosterols Does Not Affect the Uptake or Tissue Distribution of Cholesterol in Zebrafish (Danio rerio)

Frontiers in Marine Science, 2019
Increased plant oil inclusion in aquaculture feeds has led to higher dietary phytosterol concentrations and speculation about whether this affects the metabolism and health of the fish.
Michel van Spankeren, Michel van Spankeren, Nathaniel Sibinga, Øyvind Reinshol, Bente E. Torstensen, Øystein Sæle, Nina S. Liland   +6 more
doaj   +1 more source