Results 131 to 140 of about 297,274 (306)

LDL-Cholesterol: Standards of Treatment 2016: A German Perspective.

, 2016
Decreasing low-density lipoprotein cholesterol (LDL-C) is one of the few established and proven principles for the prevention and treatment of atherosclerosis.
Windler, Eberhard, Scharnagl, Hubert, Silbernagel, Günther, März, Winfried, Gouni-Berthold, Ioanna, Grammer, Tanja B, Dieplinger, Hans, Dressel, Alexander, Landmesser, Ulf, Laufs, Ulrich   +9 more
core   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

The antihyperlipidemic effect of a combined supplement of standardized dry extracts of amla (Emblica officinalis), walnut (Juglans regia), olive (Olea europaea) and red yeast rice (Monascus purpureus) powder: Reduction in circulatory low-density lipoprotein-cholesterol (LDL-C) and remnant cholesterol (RC) levels in patients with hypercholesterolemia. [PDF]

Front Pharmacol, 2023
Hermans MP, Dierckxsens Y, Janssens I, Seidel L, Albert A, Ahn SA, Rousseau MF, Khan A.   +7 more
europepmc   +1 more source

Genetic variation at the apolipoprotein B gene and associations with coronary heart disease and its factors.

, 1996
PhDCoronary heart disease (CED) is the major cause of mortality in Western societies. The main risk factors are plasma lipoprotein concentrations, smoking, blood pressure and family history.
Rajput-Williams, Jayshri
core  

Pharmacogenetic GWAS meta-analysis of LDL cholesterol response to statins [PDF]

, 2014
Cardiolog
Jukema, J.W., Consortium, GIST, Trompet, S, Krauss, R.M., Krauss, RM, Trompet, S., Postmus, I., Tardif, J.C., Psaty, B.M., GIST Consortium, Barnes, MR, Tardif, JC, Hitman, G., Psaty, BM, Postmus, I, Barnes, M.R., Jukema, JW, Deshmukh, HA, Hitman, G, Deshmukh, H.A.   +19 more
core  

Genotypes relative to LDL-cholesterol distribution for 6 variants significantly associated with LDL-cholesterol levels after logistic regression.

, 2020
The 993 AWI-Gen individuals with low and high LDL-cholesterol are included in the plots. A-D: APOB rs6752026, LDLRAP1 rs12071264, PCSK9 rs45613943 and LDLR rs72658855 show how LDL-cholesterol levels decrease with presence of the minor allele.
Robyn Kerr (8478948), Michèle Ramsay (83973), Mahtaab Hayat (8478945), Charles N. Rotimi (8478951), Frederick J. Raal (8478954), Amy R. Bentley (7634120)   +5 more
core   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Comparison of Low-Density Lipoprotein Cholesterol (LDL-C) Goal Achievement and Lipid-Lowering Therapy in the Patients With Coronary Artery Disease With Different Renal Functions. [PDF]

Front Cardiovasc Med, 2022
Zhang S, Li ZF, Shi HW, Zhang WJ, Sui YG, Li JJ, Dou KF, Qian J, Wu NQ.   +8 more
europepmc   +1 more source

Rasio Monosit LDL Cholesterol dan Neutrofil LDL Cholesterol pada Penderita TB

This study analyzes the relationship between monocyte LDL cholesterol and LDL neutrophil values ​​in patients with pulmonary TB. The research method used is descriptive observational analytic with a cross-sectional study design.
Saquro, Abdan, Muslina, Muslina, Elisma, Elisma, Agraini, Agraini, Lestari, Uce   +4 more
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source