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Why is LDL‐cholesterol bad cholesterol?

Lipid Technology, 2008
AbstractThe high circulating LDL‐cholesterol levels seen in the inherited disease familial hypercholesterolaemia cause high rates of cardiovascular disease whereas the low circulating LDL‐cholesterol levels following statin treatment cause low rates of cardiovascular disease.
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Influence of bezafibrate and colestipol on LDL-cholesterol, LDL-apolipoprotein B and HDL-cholesterol in hyperlipoproteinaemia

Atherosclerosis, 1987
A significant increase of LDL-apolipoprotein B by 13% and LDL-cholesterol by 19% was observed in a group of 9 patients with hyperlipoproteinaemia Type III after bezafibrate treatment. Additional administration of colestipol caused a significant decrease of both LDL-apolipoprotein B by 18% and LDL-cholesterol by 25%.
L, Kłosiewicz-Latoszek   +3 more
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Relationships between lymphocyte cholesterol homeostasis and LDL-cholesterol

Clinical Biochemistry, 1987
The homeostasis of cholesterol was studied in lymphocytes freshly isolated from the blood and cultured with or without low-density lipoprotein (LDL). The content of cholesterol decreased in the lymphocytes cultured without LDL, whereas LDL substituted for cellular cholesterol losses, in spite of almost suppressed LDL-receptor and lymphocyte cholesterol
R, Hambitzer, I, Melzner, O, Haferkamp
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Statins and LDL‐cholesterol lowering: an overview

Current Medical Research and Opinion, 2005
Statins have become a cornerstone of treatment for dyslipidaemia primarily due to their marked lowering of low-density lipoprotein cholesterol (LDL-C). Studies show that statin treatment typically reduces relative risk of cardiovascular disease by 24-37%, regardless of age, sex, prior history of coronary heart disease (CHD), or other co-morbid ...
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LDL-cholesterol, HDL-cholesterol or triglycerides—which is the culprit?

Diabetes Research and Clinical Practice, 2003
Dyslipidaemia in patients with type 2 diabetes commonly consists of elevated triglyceride levels; normal or slightly elevated low-density lipoprotein (LDL)-cholesterol levels with a preponderance of small, dense LDL particles; and low high-density lipoprotein (HDL)-cholesterol levels with a preponderance of small, dense HDL.
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LDL-cholesterol

2012
J. A. M. van Balen   +7 more
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