Results 261 to 270 of about 297,274 (306)

What is ‘LDL cholesterol’?

Nature Reviews Cardiology, 2019
LDL cholesterol is an important contributor to the risk of coronary heart disease, and its measurement is central to evaluating the effects of lipid-modifying therapies. Several ‘LDL-cholesterol’ assays exist but their methodologies differ, leading to between-assay heterogeneity in values of ‘LDL cholesterol’.
Michael V. Holmes, Mika Ala-Korpela
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LDL cholesterol impairs therapy

Science Signaling, 2017
A diet high in LDL cholesterol may hinder the therapeutic efficacy of tyrosine kinase inhibitors in cancer patients.
Leslie K. Ferrarelli
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Beyond lowering LDL cholesterol

Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology, 2011
Compelling evidence from randomized controlled studies demonstrated the crucial role of lowering low-density lipoprotein cholesterol (LDL-C) in the prevention of vascular events. However, not all patients with low LDL-C levels show similar reduction in event rates.
Ozgür, Bayturan, Ozan, Utük, E Murat, Tuzcu   +2 more
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LDL Cholesterol: The Lower the Better

Medical Clinics of North America, 2012
High cholesterol is often a prerequisite for atherosclerotic plaque. Low-density lipoprotein cholesterol (LDL-C) is the focus of the National Cholesterol Education Program Adult Treatment Panel guidelines. LDL-C ranges from 50 to 70 mg/dL in native hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals, who are notably ...
Seth S, Martin, Roger S, Blumenthal, Michael, Miller   +2 more
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LDL-cholesterol concentrations: a genome-wide association study

Lancet, The, 2008
BACKGROUND: LDL cholesterol has a causal role in the development of cardiovascular disease. Improved understanding of the biological mechanisms that underlie the metabolism and regulation of LDL cholesterol might help to identify novel therapeutic ...
Manjinder S Sandhu, Dawn M Waterworth, Kijoung Song   +2 more
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[LDL-Cholesterol--Is there an "LDL hypothesis"?].

Deutsche medizinische Wochenschrift (1946), 2015
The term "LDL-Hypothesis" is frequently used to describe the association between LDL cholesterol (LDL-C) and cardiovascular outcomes. In the light of recent results of randomized trials the question arises whether the term hypothesis is still adequate.
Florian, Custodis, Ulrich, Laufs
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LDL cholesterol hitches a ride

Science Translational Medicine, 2016
A new lipid-binding protein transports low-density lipoprotein across the blood vessel endothelium and might promote atherosclerosis.
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Beyond LDL Cholesterol Reduction

Circulation, 1996
Within the past decade, clinical trials of LDL-C reduction have convincingly demonstrated that LDL-C reduction in primary and secondary prevention trials can significantly reduce clinical cardiac events.1 Arteriographic investigations have demonstrated that LDL-C reduction can significantly reduce the rate of arteriographically defined disease ...
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Relationships between lymphocyte cholesterol homeostasis and LDL-cholesterol

Clinical Biochemistry, 1987
The homeostasis of cholesterol was studied in lymphocytes freshly isolated from the blood and cultured with or without low-density lipoprotein (LDL). The content of cholesterol decreased in the lymphocytes cultured without LDL, whereas LDL substituted for cellular cholesterol losses, in spite of almost suppressed LDL-receptor and lymphocyte cholesterol
R, Hambitzer, I, Melzner, O, Haferkamp
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Influence of bezafibrate and colestipol on LDL-cholesterol, LDL-apolipoprotein B and HDL-cholesterol in hyperlipoproteinaemia

Atherosclerosis, 1987
A significant increase of LDL-apolipoprotein B by 13% and LDL-cholesterol by 19% was observed in a group of 9 patients with hyperlipoproteinaemia Type III after bezafibrate treatment. Additional administration of colestipol caused a significant decrease of both LDL-apolipoprotein B by 18% and LDL-cholesterol by 25%.
L, Kłosiewicz-Latoszek, G, Nowicka, W B, Szostak, M, Naruszewicz   +3 more
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