Results 81 to 90 of about 387,407 (289)
Artificial Internalizing Receptors for Targeted Degradation of Extracellular Proteins
Small organic molecules that are anchored into the lipid bilayer of a mammalian cell and have an exofacial recognition ligand can act as artificial internalizing receptors. These receptors are an efficacious tool to selectively capture and internalize cognate antibodies from the extracellular environment in a protein‐specific manner.
Ane B. Søgaard+3 more
wiley +1 more source
These studies were undertaken to examine the effect of aging on low density lipoprotein (LDL) metabolism in the male hamster. When the hamsters were maintained on a low-cholesterol, low-triglyceride diet, rates of LDL transport in the various tissues of ...
D K Spady, J M Dietschy
doaj
Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C+27 more
core +1 more source
Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang+9 more
wiley +1 more source
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones+6 more
wiley +1 more source
Cellular cholesterol efflux and cholesterol loading capacity of serum: effects of LDL-apheresis
High LDL-cholesterol (LDL-C) characterizes familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH). LDL-apheresis, used in these patients to reduce LDL-C levels, has been shown to also affect HDL levels and composition.
M.P. Adorni+9 more
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Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]
BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia+7 more
core +3 more sources
Influence of an atherogenic diet on the structure of swine low density lipoproteins
Five groups of three swine each were fed a basal diet supplemented with 15% tallow and either 0.0, 1.0, 1.5, 2.0%, or 2.5% cholesterol. The animals were studied over a period of 9 weeks to observe changes in plasma lipids and low density lipoproteins ...
H J Pownall+5 more
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The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad+9 more
wiley +1 more source
Subcellular localization of nonesterified cholesterol has been determined in normal human fibroblasts from cultures incubated with human low density lipoprotein (LDL).
H S Kruth+4 more
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