Results 241 to 250 of about 2,770,733 (305)

Economic and productivity outcomes of workplace health programmes incorporating blood-based laboratory screening: a systematic review. [PDF]

BMC Health Serv Res
Swadźba D, Makuch S, Agrawal S.
europepmc   +1 more source

Dietary Flavonoid Hyperoside Ameliorates High‐Fat Diet‐Induced Type 2 Diabetes Mellitus by Enhancing Brown Adipose Tissue Thermogenesis, White Adipose Tissue Browning, and Gut Microbiota Remodeling

Phytotherapy Research, EarlyView.
Hyperoside ameliorates metabolic dysfunction in high‐fat diet‐induced type 2 diabetic mice, accompanied by enhanced brown adipose tissue thermogenic activity, inguinal white adipose tissue browning‐related changes, reduced M1 macrophage polarization, and gut microbiota remodeling.
WeiFeng Cai, WenXin Zeng, Yu Luo, Qiang Liu, CuiPing Jiang, YanKui Yi, JieYu Chen, ChunYan Shen   +7 more
wiley   +1 more source

Impact of Dyslipidemia on Clinical Outcomes Among Cancer Patients Treated With Immune Checkpoint Inhibitors. [PDF]

Cancer Med
Liang Y, Maeda O, Ishida S, Zennami K, Kimura T, Inoue S, Sano T, Sano Y, Naito Y, Miyata K, Shimizu D, Nishida K, Chrétien B, Kanda M, Akamatsu S, Ando Y.   +15 more
europepmc   +1 more source

Cinnamic Acid Attenuates Ethanol‐Exacerbated Hepatocyte Pyroptosis in Type 2 Diabetes via AMPK‐Mediated NLRP3/GSDMD Inhibition

Phytotherapy Research, EarlyView.
CA directly binds to and activates AMPK to suppress NLRP3/GSDMD signaling, thereby alleviating hepatocyte pyroptosis in T2DM mice. ABSTRACT Type 2 diabetes mellitus (T2DM) is frequently accompanied by chronic ethanol (ET) consumption, which worsens metabolic dysregulation and organ damage.
Huaiying Tang, Qin Xiang, Yue Zhang, Yu Zhang, Xiangxiang Fu, Liming Tan, Yongli Zhang, Siqi Li, Dong Gong, Xu Guo, Yonghong Zhang, Li Chen, Tao Zheng, Qibin Wang   +13 more
wiley   +1 more source

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

Small, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo, Serena Renzi, Martina B. Violatto, Leila Altigieri, Anna L. Capriotti, Andrea Cerrato, Aldo Laganà, Luca Digiacomo, Erica Quagliarini, Antonio Minopoli, Massimiliano Papi, Daniela Pozzi, Carlo A. Scirè, Pietro Invernizzi, Paolo Bigini, Giulio Caracciolo   +15 more
wiley   +1 more source

Screening Signals of Reference-Defined Metabolic Syndrome Using HbA1c and LDL Cholesterol: An Explainable Machine Learning Study. [PDF]

Diagnostics (Basel)
Demir O.
europepmc   +1 more source

Serum versus lithium-heparin plasma for lipid testing: matrix-related bias and calculated LDL-C classification. [PDF]

J Clin Pathol
Kouched N, Jmal L, Zaouche K, Dhieb A, Guidara R, Jmal A.   +5 more
europepmc   +1 more source

Associations between early improvements in atherogenic lipids and reported dietary changes after RYGB: a pilot exploratory analysis in women with type 2 diabetes. [PDF]

Clinics (Sao Paulo)
Lemos GO, Prudêncio APA, Santos RHN, Neto JV, Marcadenti A, Fisberg RM, Menezes H, Heymsfield SB, Torrinhas RS, Waitzberg DL.   +9 more
europepmc   +1 more source