Results 41 to 50 of about 882,729 (197)

Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels

open access: yesJournal of Lipid Research, 2010
Over the past several years, proprotein convertase subtilisin kexin type 9 (PCSK9) has gained significant attention as a key regulator of serum LDL-cholesterol (LDL-C) levels.
Jason S. Troutt   +3 more
doaj   +1 more source

Cellular cholesterol efflux and cholesterol loading capacity of serum: effects of LDL-apheresis

open access: yesJournal of Lipid Research, 2012
High LDL-cholesterol (LDL-C) characterizes familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH). LDL-apheresis, used in these patients to reduce LDL-C levels, has been shown to also affect HDL levels and composition.
M.P. Adorni   +9 more
doaj   +1 more source

Effect of Zinc Supplementation on Triglyceride, Cholesterol, LDL, and HDL Levels in Zinc-Deficient Hemodialysis Patients [PDF]

open access: yesRenal Failure, 2009
Zinc deficiency is known to occur in widely diverse areas of world. It has now been recognized in many disease states, such as ESRD patients on maintenance hemodialysis (HD). The purpose of this research was to study the effects of zinc supplementation on the concentration of serum zinc, total cholesterol, triglyceride, and cholesterol fractions (HDL ...
Jamshid, Roozbeh   +8 more
openaire   +2 more sources

Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-).

open access: yesJournal of Lipid Research, 1994
Using ion exchange high pressure liquid chromatography, total plasma low density lipoprotein (LDL) from 30 hypercholesterolemic and 10 normocholesterolemic cynomolgus monkeys was subfractionated into unmodified LDL (n-LDL) and more negatively charged LDL
H.N. Hodis   +7 more
doaj   +1 more source

Elevated low-density lipoprotein cholesterol (LDL-C) enhances proerectile neurotransmission in the corpus cavernosum [PDF]

open access: yesInternational Journal of Impotence Research, 1999
Hypercholesterolaemia is thought to foster atherosclerosis and impotence through its effects on vascular endothelium. In this study, we investigated the pharmacological changes in rabbit corpus cavernosum (CC) secondary to incubation with lysolecithin and hypercholesterolaemia.
Srilatha, B.   +3 more
openaire   +2 more sources

Lipid Profile (Total Cholesterol, LDL, HDL, Triglyceride) of Injection Contraceptive Acceptors in Semarang

open access: yesJournal of Maternal and Child Health, 2021
Background: Hormonal injectable contraceptives are the most common choice taken by women. The 3-month injection of contraception is DMPA, one of the most effective contraceptive methods currently used. Using injectable contraceptives, especially DMPA, influences fat metabolism, especially lipoproteins.
Surati Surati, Djoko Priyatno
openaire   +1 more source

Subcellular localization and quantification of cholesterol in cultured human fibroblasts exposed to human low density lipoprotein

open access: yesJournal of Lipid Research, 1982
Subcellular localization of nonesterified cholesterol has been determined in normal human fibroblasts from cultures incubated with human low density lipoprotein (LDL).
H S Kruth   +4 more
doaj   +1 more source

Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol

open access: yesNew England Journal of Medicine, 2019
Background Short‐term studies have shown that bempedoic acid, an inhibitor of ATP citrate lyase, reduces levels of low‐density lipoprotein (LDL) cholesterol.
K. Ray   +7 more
semanticscholar   +1 more source

Effects of inhibiting cholesterol absorption and synthesis on cholesterol and lipoprotein metabolism in hypercholesterolemic non-insulin-dependent diabetic men.

open access: yesJournal of Lipid Research, 1996
Effectiveness of a simultaneous inhibition of cholesterol absorption and synthesis, caused by sitostanol ester margarine and pravastatin, was studied to control mild hypercholesterolemia in men with non-insulin-dependent diabetes mellitus (NIDDM) (n = 8).
H Gylling, T A Miettinen
doaj   +1 more source

Cardiovascular outcomes and LDL-cholesterol levels in EMPA-REG OUTCOME

open access: yesDiabetes & Vascular Disease Research, 2020
Objective: It is well established that higher low-density lipoprotein (LDL)-cholesterol levels are associated with increased cardiovascular risk. We analyzed whether effects of empagliflozin on cardiovascular outcomes varied by different LDL-cholesterol ...
Gisle Langslet   +6 more
doaj   +1 more source

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