Results 51 to 60 of about 882,729 (197)

Evolocumab for Early Reduction of LDL-Cholesterol Levels in Patients with Acute Coronary Syndromes (EVOPACS).

Journal of the American College of Cardiology, 2019
BACKGROUND While guidelines recommend in-hospital initiation of high-intensity statin therapy in patients with acute coronary syndromes (ACS), low-density lipoprotein cholesterol (LDL-C) target levels are frequently not attained.
K. Koskinas, S. Windecker, G. Pedrazzini, C. Mueller, S. Cook, C. Matter, O. Muller, J. Häner, B. Gencer, C. Crljenica, P. Amini, Olga Deckarm, J. Iglesias, L. Räber, D. Heg, F. Mach   +15 more
semanticscholar   +1 more source

A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke.

New England Journal of Medicine, 2019
BACKGROUND The use of intensive lipid-lowering therapy by means of statin medications is recommended after transient ischemic attack (TIA) and ischemic stroke of atherosclerotic origin.
P. Amarenco, Jong-suk Kim, J. Labreuche, Hugo Charles, J. Abtan, Y. Béjot, L. Cabrejo, J. Cha, G. Ducrocq, M. Giroud, C. Guidoux, Cristina Hobeanu, Yong-Jae Kim, B. Lapergue, Philippa C. Lavallée, Byung‐Chul Lee, K. Lee, D. Leys, M. Mahagne, E. Meseguer, N. Nighoghossian, F. Pico, Y. Samson, I. Sibon, P. Steg, S. Sung, P. Touboul, E. Touzé, O. Varenne, E. Vicaut, Nessima Yelles, E. Bruckert, T. Investigators   +32 more
semanticscholar   +1 more source

The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials

The Lancet, 2012
Summary Background Statins reduce LDL cholesterol and prevent vascular events, but their net effects in people at low risk of vascular events remain uncertain.
B. Mihaylova, J. Emberson, L. Blackwell, Anthony C. Keech, J. Simes, Elizabeth H Barnes, M. Voysey, Alastair Gray, R. Collins, C. Baigent   +9 more
semanticscholar   +1 more source

Quantitation of the in vitro free cholesterol exchange of human red cells and lipoproteins

Journal of Lipid Research, 1970
The exchange of free cholesterol in vitro between human red blood cells and low density lipoproteins (LDL) was quantified. The flux of sterol between LDL and red cells was relatively constant over a wide range of concentrations of free cholesterol in ...
STEVEN H. QUARFORDT, HELEN L. HILDERMAN
doaj   +1 more source

Standardization of Apolipoprotein B, LDL‐Cholesterol, and Non‐HDL‐Cholesterol

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Concern continues about whether the measurement of apolipoprotein B (apoB) is adequately standardized, and therefore, whether apoB should be applied widely in clinical care. This concern is misplaced.
John H. Contois, Michel R. Langlois, Christa Cobbaert, Allan D. Sniderman   +3 more
doaj   +1 more source

Low-density lipoprotein cholesterol and risk of COPD: Copenhagen General Population Study

ERJ Open Research, 2023
Background Randomised controlled trials found that low-density lipoprotein (LDL) cholesterol-lowering statins increase lung function and possibly decrease rate of exacerbations in individuals with COPD.
Josefine Freyberg, Eskild M. Landt, Shoaib Afzal, Børge G. Nordestgaard, Morten Dahl   +4 more
doaj   +1 more source

Interaction of different lipoprotein types with cholesterol at the air/water interface

Heliyon, 2020
Cholesterol (Chol) interacts with lipoproteins, in order to be transported through the aqueous bloodstream. High density lipoproteins (HDL) and low density lipoproteins (LDL) transport cholesterol differently, a result that may be due to a difference in ...
Ryota Ninomiya, Cathy E. McNamee
doaj   +1 more source

Distinct mechanisms of plasma LDL lowering by dietary fiber in the guinea pig: specific effects of pectin, guar gum, and psyllium

Journal of Lipid Research, 1995
Pectin (PE), guar gum (GG), and psyllium (PSY) lower plasma low density lipoprotein (LDL) cholesterol concentrations in guinea pigs with different orders of magnitude by inducing defined alterations in hepatic cholesterol homeostasis (Fernandez et al ...
M L Fernandez
doaj   +1 more source

Sialic acid content of low density lipoprotein and its relation to lipid concentrations and metabolism of low density lipoprotein and cholesterol

Journal of Lipid Research, 2000
A low sialic acid content in low density lipoprotein (LDL) has been associated with atherogenicity and coronary artery disease (CAD) in many but not all studies. We investigated associations of the sialic acid-to-apolipoprotein B (apoB) ratio of LDL with
Nina Lindbohm, Helena Gylling, Tatu A. Miettinen   +2 more
doaj   +1 more source

Genetic associations between serum low LDL-cholesterol levels and variants in LDLR, APOB, PCSK9 and LDLRAP1 in African populations.

PLoS ONE, 2020
Non-communicable diseases, including cardiovascular diseases (CVDs), are increasing in African populations. High serum low density lipoprotein cholesterol (LDL-cholesterol) levels are a known risk factor for CVDs in European populations, but the link ...
Mahtaab Hayat, Robyn Kerr, Amy R Bentley, Charles N Rotimi, Frederick J Raal, Michèle Ramsay   +5 more
doaj   +1 more source