Results 101 to 110 of about 1,523,799 (296)

Direct modulation of G protein-gated inwardly rectifying potassium (GIRK) channels

open access: yesFrontiers in Physiology
Ion channels play a pivotal role in regulating cellular excitability and signal transduction processes. Among the various ion channels, G-protein-coupled inwardly rectifying potassium (GIRK) channels serve as key mediators of neurotransmission and ...
Ha Nguyen   +2 more
doaj   +1 more source

Charge-induced phase separation in lipid membranes [PDF]

open access: yes, 2014
The phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibility temperatures in several binary and ternary lipid mixtures of ...
Andelman, David   +5 more
core   +2 more sources

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

open access: yesAdvanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen   +30 more
wiley   +1 more source

The Effects of Licorice Root Powder (Glycyrrhriza glabra) on Performance, Serum Parameters, Egg Yolk Cholesterol and Antioxidant Capacity of Laying Japanese Quail

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2018
This study was conducted with the objectives to determine the effects of licorice root powder (Glycyrrhriza glabra) on performance, serum parameters, egg yolk cholesterol and antioxidant capacity in laying Japanese quail.
Sibel Canoğulları Doğan   +4 more
doaj   +1 more source

Potential of Lactic Acid Bacteria Isolated From Dangke and Indonesian Beef as Hypocholesterolaemic Agent [PDF]

open access: yes, 2017
Lactobacillus fermentum strains were successfully isolated from dangke which was a fresh cheese-like product originating from Enrekang, South Sulawesi Province, Indonesia.
Arief, I. I. (I)   +3 more
core  

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

Nonlinear relationship between serum 25-hydroxyvitamin D and lipid profile in Chinese adults

open access: yesFrontiers in Nutrition
BackgroundPrevious studies on the liner associations between serum 25-hydroxyvitamin D [25(OH)D] levels and lipid profiles revealed ambiguous findings.
Qianqian Wang   +11 more
doaj   +1 more source

Control of Cholesterol Metabolism and Plasma High-Density Lipoprotein Levels by microRNA-144 [PDF]

open access: bronze, 2013
Cristina M. Ramírez   +15 more
openalex   +1 more source

Ursolic acid enhances macrophage autophagy and attenuates atherogenesis [PDF]

open access: yes, 2016
Macrophage autophagy has been shown to be protective against atherosclerosis. We previously discovered that ursolic acid (UA) promoted cancer cell autophagy.
Fan, Daping   +7 more
core   +2 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

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