Results 31 to 40 of about 2,069,563 (390)

Structure of the Myelin Sheath Proteolipid Plasmolipin (PLLP) in a Ganglioside-Containing Lipid Raft

Frontiers in Bioscience-Landmark, 2023
Background: Plasmolipin (PLLP) is a membrane protein located in lipid rafts that participates in the formation of myelin. It is also implicated in many pathologies, such as neurological disorders, type 2 diabetes, and cancer metastasis.
Fodil Azzaz, Morgane Mazzarino, Henri Chahinian, Nouara Yahi, Coralie Di Scala, Jacques Fantini   +5 more
doaj   +1 more source

Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites

Gut, 2020
Objective Non-alcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma (HCC) is an increasing healthcare burden worldwide. We examined the role of dietary cholesterol in driving NAFLD–HCC through modulating gut microbiota and its ...
Xiang Zhang, O. Coker, E. Chu, Kaili Fu, H. C. Lau, Yi-Xiang J. Wang, A. Chan, Hong Wei, Xiaoyong Yang, J. Sung, Jun Yu   +10 more
semanticscholar   +1 more source

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin, Amento, Edward P, Kong, Raymond, Liu, David, Lundry, Jason, Madasamy, Shanmugavel, Robinson, J Paul, Wu, Alan HB   +7 more
core   +1 more source

Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet

Physiological Reports, 2022
Rats selectively bred for the high intrinsic aerobic capacity runner (HCR) or low aerobic capacity runner (LCR) show pronounced differences in susceptibility for high‐fat/high sucrose (HFHS) diet‐induced hepatic steatosis and insulin resistance ...
Harrison D. Stierwalt, E. Matthew Morris, Adrianna Maurer, Udayan Apte, Kathryn Phillips, Tiangang Li, Grace M. E. Meers, Lauren G. Koch, Steven L. Britton, Greg Graf, R. Scott Rector, Kelly Mercer, Kartik Shankar, John P. Thyfault   +13 more
doaj   +1 more source

Vascular robustness: The missing parameter in cardiovascular risk prediction

Preventive Medicine Reports, 2018
Undetected high risk for premature death of cardiovascular disease (CVD) among individuals with low-to-moderate risk factor scores is an acknowledged obstacle to CVD prevention.
Lutz E. Kraushaar, Alexander Dressel, Alexander Maßmann   +2 more
doaj   +1 more source

Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease.

Journal of the American College of Cardiology, 2020
BACKGROUND Genetic, observational, and clinical intervention studies indicate that circulating levels of triglycerides and cholesterol transported in triglyceride-rich lipoproteins (remnant cholesterol) can predict cardiovascular events.
O. Castañer, X. Pintó, I. Subirana, A. Amor, E. Ros, Á. Hernáez, M. Martínez-González, D. Corella, J. Salas‐Salvadó, R. Estruch, J. Lapetra, E. Gómez-Gracia, Á. Alonso-Gómez, M. Fiol, L. Serra-Majem, E. Corbella, D. Benaiges, J. Sorlí, M. Ruíz-Canela, N. Babio, L. T. Sierra, E. Ortega, M. Fitó   +22 more
semanticscholar   +1 more source

Cholesterol oxides inhibit cholesterol esterification by lecithin: cholesterol acyl transferase

Brazilian Journal of Pharmaceutical Sciences, 2009
Cholesterol oxides are atherogenic and can affect the activity of diverse important enzymes for the lipidic metabolism. The effect of 7β-hydroxycholesterol, 7-ketocholesterol, 25-hydroxycholesterol, cholestan-3β,5α,6β-triol,5,6β ...
Eder de Carvalho Pincinato, Patricia Moriel, Dulcinéia Saes Parra Abdalla   +2 more
doaj   +1 more source

Apolipoprotein B and Non-HDL Cholesterol Better Reflect Residual Risk Than LDL Cholesterol in Statin-Treated Patients.

Journal of the American College of Cardiology, 2021
BACKGROUND In cholesterol guidelines, low-density lipoprotein (LDL) cholesterol remains the primary target while apolipoprotein B (apoB) and non-high-density lipoprotein (non-HDL) cholesterol are secondary targets.
C. Johannesen, M. Mortensen, A. Langsted, B. Nordestgaard   +3 more
semanticscholar   +1 more source

Effect of oral cinnamon intervention on metabolic profile and body composition of Asian Indians with metabolic syndrome: a randomized double -blind control trial

Lipids in Health and Disease, 2017
Background Nutritional modulation remains central to the management of metabolic syndrome. Intervention with cinnamon in individuals with metabolic syndrome remains sparsely researched.
Sonal Gupta Jain, Seema Puri, Anoop Misra, Seema Gulati, Kalaivani Mani   +4 more
doaj   +1 more source

Cholesterol-induced toxicity: An integrated view of the role of cholesterol in multiple diseases.

Cell Metabolism, 2021
High levels of cholesterol are generally considered to be associated with atherosclerosis. In the past two decades, however, a number of studies have shown that excess cholesterol accumulation in various tissues and organs plays a critical role in the ...
Yongfeng Song, Junjun Liu, Ke Zhao, Ling Gao, Jiajun Zhao   +4 more
semanticscholar   +1 more source